Winssinger, Nicolas

Title	Published in	Year	Views	Downloads
Self-assembled proteomimetic (SAP) with antibody-like binding from short PNA–peptide conjugates	Proceedings of the National Academy of Sciences of the United States of America	2025	98	184
Photocatalytic Microenvironment Proteomics of Thiol-Mediated Uptake	JACS Au	2025	19	22
Sequencing of _D/_L -DNA and XNA by Templated-Synthesis	Journal of the American Chemical Society	2025	32	35
DNA-Drug Conjugates (DDCs) for computed delivery		2025	40	34
Red‐Shifted Bioluminescence Using Substrate‐Fluorophore Conjugates	Helvetica chimica acta	2025	37	0
Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability	Nature communications	2025	167	52
PTPRZ1-targeting RNA CAR T cells exert antigen-specific and bystander antitumor activity in glioblastoma	Cancer immunology research	2024	302	301
Total Synthesis of Tagitinins, Goyazensolide and Related Furanoheliangolides and their Covalent Interaction with Importin‐5 (IPO5)	Helvetica chimica acta	2024	52	47
Bright Red Bioluminescence from Semisynthetic NanoLuc (sNLuc)	ACS chemical biology	2024	95	64
Reversible Anticoagulants: Inspired by Nature, Designed for Safety	TheScienceBreaker	2024	25	26
Translation of Deoxyribonucleic Acid into Synthetic Alpha Helical Peptides for Darwinian Evolution	JACS Au	2024	29	28
Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains	ACS chemical biology	2024	26	44
Impact of charges on the hybridization kinetics and thermal stability of PNA duplexes	Organic & biomolecular chemistry	2024	62	24
Development of supramolecular anticoagulants with on-demand reversibility	Nature biotechnology	2024	201	278
Supernatural: Artificial Nucleobases and Backbones to Program Hybridization-Based Assemblies and Circuits	Bioconjugate chemistry	2023	200	113
Rapid Synthesis of Propargyl‐γ‐Modified Peptide Nucleic Acid Monomers for Late‐Stage Functionalization of Oligomers	Helvetica chimica acta	2023	120	57
Two‐Helix Supramolecular Proteomimetic Binders Assembled via PNA‐Assisted Disulfide Crosslinking	ChemBioChem	2023	305	0
PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma		2023	244	548
Pseudo-Complementary G:C Base Pair for Mixed Sequence dsDNA Invasion and Its Applications in Diagnostics (SARS-CoV-2 Detection)	JACS Au	2023	125	185
SCS Spring Meeting 2022 on Biosupramolecular Chemistry	Chimia : Frontiers in Ultrafast Spectroscopy and Dynamics	2022	247	140
Biosupramolecular networks: Taking inspiration from nature to create powerful synthetic platforms	Current opinion in chemical biology	2022	308	314
A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules	Nature chemistry	2022	325	0
Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization	Angewandte Chemie. International edition in English	2022	284	237
DNA‐Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution	Angewandte Chemie	2022	178	434
Withaferin A, a polyfunctional pharmacophore that includes covalent engagement of IPO5, is an inhibitor of influenza A replication	Bioorganic & medicinal chemistry	2022	273	172
Synthesis of Protein-Oligonucleotide Conjugates	Biomolecules	2022	59	59
Combining recombinase polymerase amplification and DNA-templated reaction for SARS-CoV-2 sensing with dual fluorescence and lateral flow assay output	Biopolymers	2022	366	166
Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond	Frontiers in oncology	2021	81	48
Kinesin-1 activity recorded in living cells with a precipitating dye	Nature Communications	2021	533	209
Suprastapled Peptides: Hybridization-Enhanced Peptide Ligation and Enforced α-Helical Conformation for Affinity Selection of Combinatorial Libraries	Journal of the American Chemical Society	2021	306	572
SARS-COV2- infection as a trigger of humoral response against apolipoprotein A-1	EAS Congress 2021	2021	384	38
Luciferase Controlled Protein Interactions	Journal of the American Chemical Society	2021	337	351
Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2	Chimia	2021	301	238
Total Syntheses of Paraconic Acids and 1,10-seco-Guaianolides via a Barbier Allylation/Translactonization Cascade of 3-(Bromomethyl)-2(5H)-furanone	Organic Letters	2021	551	235
Photocatalysis in Chemical Biology: Extending the Scope of Optochemical Control and Towards New Frontiers in Semisynthetic Bioconjugates and Biocatalysis	Helvetica chimica acta	2021	319	348
Oligonucleotide Phosphorothioates Enter Cells by Thiol‐Mediated Uptake	Angewandte Chemie: International Edition	2021	304	826
Biosupramolecular Systems: Integrating Cues into Responses	Journal of the American Chemical Society	2021	440	285
A minimal hybridization chain reaction (HCR) system using peptide nucleic acids	Chemical Science	2021	271	226
Synthesis of α-exo-Methylene-γ-butyrolactones: Recent Developments and Applications in Natural Product Synthesis	Synthesis	2021	435	551
Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides	ACS Central Science	2021	358	470
SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1	European Journal of Clinical Investigation	2021	424	271
Flipper Probes for the Community	Chimia	2021	468	287
Dual Bcl-XL /Bcl-2 inhibitors discovered from DNA-encoded libraries using a fragment pairing strategy	Bioorganic & Medicinal Chemistry	2021	253	149
Probing for Thiol-Mediated Uptake into Bacteria	ChemBioChem	2020	472	493
Sense-and-Release Logic-Gated Molecular Network Responding to Dimeric Cell Surface Proteins	Journal of the American Chemical Society	2020	397	301
PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule Libraries	Peptide Nucleic Acids: Methods and Protocols	2020	499	1
Smartphone DNA or RNA Sensing Using Semisynthetic Luciferase-Based Logic Device	ACS Sensors	2020	421	632
Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma	PLOS ONE	2020	470	354
Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9	Molecular and Cellular Proteomics	2020	485	283
The RB596 antibody recognizes a linear epitope from the spike S protein from SARS-CoV-2	Antibody Reports	2020	237	86
Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90	Frontiers in oncology	2020	141	73
Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks	Journal of the American Chemical Society	2020	491	4
Enhanced SNP-sensing using DNA-templated reactions through confined hybridization of minimal substrates (CHOMS)	Chemical Science	2020	372	253
Kilian Muñiz (1970–2020)	Angewandte Chemie: International Edition	2020	403	0
Caprin‐1 Promotes Cellular Uptake of Nucleic Acids with Backbone and Sequence Discrimination	Helvetica Chimica Acta	2020	501	328
Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functions	ACS Chemical Biology	2020	525	522
PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins	Bioorganic & Medicinal Chemistry	2020	418	3
Luciferase-Induced Photouncaging: Bioluminolysis	Angewandte Chemie: International Edition	2019	516	626
Coupling of DNA Circuit and Templated Reactions for Quadratic Amplification and Release of Functional Molecules	Journal of the American Chemical Society	2019	477	446
Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures	Chemical Science	2019	516	306
Sphingolipids and membrane targets for therapeutics	Current Opinion in Chemical Biology	2019	561	3
Turn On of a Ruthenium(II) Photocatalyst by DNA-Templated Ligation	Chemistry - A European Journal	2019	599	580
Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics	Current Opinion in Chemical Biology	2019	504	968
Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology	Chemistry - A European Journal	2019	592	652
Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function	eLife	2018	585	767
Synthesis of deoxyelephantopin analogues	Journal of Antibiotics	2018	537	310
Double-Stranded RNA-Specific Templated Reaction with Triplex Forming PNA	Helvetica Chimica Acta	2018	596	1,170
Luciferase-induced photoreductive uncaging of small-molecule effectors	Nature Communications	2018	626	337
Editorial overview: Synthetic biomolecules	Current Opinion in Chemical Biology	2018	472	0
Peptide nucleic acid-templated selenocystine–selenoester ligation enables rapid miRNA detection	Chemical Science	2018	588	296
Biography of Professor Nicolaou: a journey to the extremes of molecular complexity	Journal of Antibiotics	2018	529	2
Ruthenium-based Photocatalysis in Templated Reactions	Chimia	2018	589	330
Accelerating Turnover Frequency in Nucleic Acid Templated Reactions	Bioconjugate Chemistry	2018	549	404
Rapid and scalable synthesis of chiral bromolactones as precursors to α-exo-methylene-γ-butyrolactone-containing sesquiterpene lactones	Tetrahedron	2018	513	631
Bioorthogonal Chemistry	Chimia	2018	443	383
Covalent inhibitors : an opportunity for rational target selectivity	Current opinion in chemical biology	2017	626	551
Kinase-templated abiotic reaction	Chemical science	2017	560	255
Following the Lead from Nature with Covalent Inhibitors	Chimia	2017	528	0
Dynamic cooperative glycan assembly blocks the binding of bacterial lectins to epithelial cells	Angewandte Chemie	2017	587	250
Critical Analysis of Rate Constants and Turnover Frequency in Nucleic Acid-Templated Reactions: Reaching Terminal Velocity	Journal of the American Chemical Society	2017	858	695
Facile access to modified and functionalized PNAs through Ugi-based solid phase oligomerization	Bioorganic & Medicinal Chemistry	2017	584	915
Rapid and Scalable Synthesis of cis-Fused Guaiane-Type Sesquiterpenes	European journal of organic chemistry	2016	633	3
Activation of Cell-Penetrating Peptides with Ionpair−π Interactions and Fluorophiles	Journal of the American Chemical Society	2016	737	473
A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer	Oncotarget	2016	576	0
Allosterically Regulated Phosphatase Activity from Peptide-PNA Conjugates Folded Through Hybridization	Angewandte Chemie	2016	621	9
Duplex formation and secondary structure of γ-PNA observed by NMR and CD	Biophysical chemistry	2016	816	2
Divergent synthesis and identification of the cellular targets of deoxyelephantopins	Nature communications	2016	610	405
One-Step Derivatization of Reducing Oligosaccharides for Rapid and Live-Cell Compatible Chelation-Assisted CuAAC Conjugation	ChemBioChem	2016	669	5
Nucleic Acid Templated Chemical Reaction in a Live Vertebrate	ACS central science	2016	690	304
High Spatial Resolution Imaging of Endogenous Hydrogen Peroxide in Living Cells by Solid-State Fluorescence	ChemBioChem	2016	551	0
Novel PTP1B inhibitors identified by DNA display of fragment pairs	Bioorganic & medicinal chemistry letters	2016	691	10
Screening for covalent inhibitors using DNA-display of small molecule libraries functionalized with cysteine reactive moieties	MedChemComm	2016	638	12
Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules	Angewandte Chemie	2015	777	13
HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas	Cancer letters	2015	657	2
PNA-encoded chemical libraries	Current opinion in chemical biology	2015	663	12
Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne	Bioconjugate chemistry	2015	636	6
DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules	Chemical science	2015	799	12
DNA display of glycoconjugates to emulate oligomeric interactions of glycans	Beilstein journal of organic chemistry	2015	657	325
In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis	Chemical communications	2015	689	8
PNA as a Biosupramolecular Tag for Programmable Assemblies and Reactions	Accounts of chemical research	2015	688	11
Rapid miRNA Imaging in Cells Using Fluorogenic Templated Staudinger Reaction Between PNA-Based Probes	Peptide Nucleic Acids : Methods and Protocols	2014	758	0
Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway	Organic & biomolecular chemistry	2014	765	14
Assembly of PNA-Tagged Small Molecules, Peptides, and Carbohydrates onto DNA Templates: Programming the Combinatorial Pairing and Inter-ligand Distance	Peptide Nucleic Acids : Methods and Protocols	2014	728	0
PNA-Encoded Synthesis (PES) of a 10 000-Member Hetero-Glycoconjugate Library and Microarray Analysis of Diverse Lectins	ChemBioChem	2014	632	4
A LecA Ligand Identified from a Galactoside-Conjugate Array Inhibits Host Cell Invasion by Pseudomonas aeruginosa	Angewandte Chemie	2014	581	5
Reactions Templated by Nucleic Acids: More Ways to Translate Oligonucleotide-Based Instructions into Emerging Function	Angewandte Chemie	2013	708	13
Self-Assembled Antibody Multimers through Peptide Nucleic Acid Conjugation	Journal of the American Chemical Society	2013	655	8
Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis	European journal of organic chemistry	2013	676	6
Selective affinity-based probe for oncogenic kinases suitable for live cell imaging	Chemical science	2013	724	9
Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates	Chemical communications	2013	679	4
Nucleic Acid-programmed Assemblies: Translating Instruction into Function in Chemical Biology	Chimia	2013	692	621
Picture Perfect: DNA-Templated Photoaffinity Labeling	ChemBioChem	2013	701	6
Detection of miRNA in Live Cells by Using Templated Ru^II-Catalyzed Unmasking of a Fluorophore	Chemistry	2013	725	8
Nucleic Acid-tagged Peptides: Encoding Libraries and Controlling Dimerization and Conformation	Chimia	2013	686	4
DNA as a Platform to Program Assemblies with Emerging Functions in Chemical Biology	Israel Journal of Chemistry	2013	659	0
DNA display of PNA-tagged ligands: A versatile strategy to screen libraries and control geometry of multidentate ligands	Artificial DNA, PNA & XNA	2012	615	399
Diversity-Oriented Synthesis of Diverse Polycyclic Scaffolds Inspired by the Logic of Sesquiterpene Lactones Biosynthesis	Angewandte Chemie	2012	671	4
Expanding the Scope of PNA-Encoded Synthesis (PES): Mtt-Protected PNA Fully Orthogonal to Fmoc Chemistry and a Broad Array of Robust Diversity-Generating Reactions	Chemistry	2012	730	9
Asymmetric Synthesis of Pochonin E and F, Revision of Their Proposed Structure, and Their Conversion to Potent Hsp90 Inhibitors	Chemistry	2012	673	3
Photoreductive Uncaging of Fluorophore in Response to Protein Oligomers by Templated Reaction in Vitro and in Cellulo	Journal of the American Chemical Society	2012	650	8
Polyubiquitination of Transforming Growth Factor β(TGFβ)-associated Kinase 1 Mediates Nuclear Factor-κB Activation in Response to Different Inflammatory Stimuli	The Journal of biological chemistry	2012	665	0
Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries	Organic & biomolecular chemistry	2012	665	5
Nucleic Acid Templated Uncaging of Fluorophores Using Ru-Catalyzed Photoreduction with Visible Light	Organic letters	2012	670	7
Synthesis of deguelin–biotin conjugates and investigation into deguelin's interactions	Bioorganic & medicinal chemistry	2012	667	0
Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells	Chemical communications	2011	591	694
Rapid fluorescence imaging of miRNAs in human cells using templated Staudinger reaction	Chemical science	2011	661	1,010
Translating instructions into function by nucleic acid programmed self-assembly	L'Actualité chimique	2011	679	0
Cysteine Mapping in Conformationally Distinct Kinase Nucleotide Binding Sites: Application to the Design of Selective Covalent Inhibitors	Journal of medicinal chemistry	2011	642	2
DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker	Chemical communications	2011	608	8
Combinatorial Self-Assembly of Glycan Fragments into Microarrays	ChemBioChem	2011	654	2
DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles	Chemical science	2011	683	5
Nucleic Acid-Templated Energy Transfer Leading to a Photorelease Reaction and its Application to a System Displaying a Nonlinear Response	Journal of the American Chemical Society	2011	666	6
In Vivo Efficacy of Natural Product-Inspired Irreversible Kinase Inhibitors	ChemBioChem	2010	610	0
Ligand dimerization programmed by hybridization to study multimeric ligand–receptor interactions	Chemical communications	2010	583	0
The Novel Hsp90 Inhibitor NXD30001 Induces Tumor Regression in a Genetically Engineered Mouse Model of Glioblastoma Multiforme	Molecular cancer therapeutics	2010	632	0
Clickable peptide nucleic acids (cPNA) with tunable affinity	Chemical communications	2010	614	4
Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL	ChemMedChem	2010	550	0
Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation	Proteomics	2010	608	0
Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular Process	The Journal of biological chemistry	2010	548	0
Metathesis Reactions in Solid-Phase Organic Synthesis	Metathesis in Natural Product Synthesis: Strategies, Substrates and Catalysts	2010	691	0
Concise Modular Asymmetric Synthesis of Deguelin, Tephrosin and Investigation into Their Mode of Action	Chemistry	2010	637	0
Selection of bead-displayed, PNA-encoded chemicals	JMR. Journal of molecular recognition	2010	624	0
The molecular chaperone Hsp90alpha is required for meiotic progression of spermatocytes beyond pachytene in the mouse	PloS one	2010	769	472
Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases	Chemistry	2009	542	0
Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin	Chemistry	2009	631	0
Self-Assembly of PNA-Encoded Peptides into Microarrays	Peptide Microarrays: Methods and Protocols	2009	773	0
Synthesis of pochoxime prodrugs as potent HSP90 inhibitors	Bioorganic & medicinal chemistry letters	2009	557	0
Hsp90 Inhibition with Resorcylic Acid Lactones (RALs)	Current topics in medicinal chemistry	2009	732	0
The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR ¹⁵N chemical shifts	Biophysical chemistry	2009	675	0
Inhibition of HSP90 with Pochoximes: SAR and Structure-Based Insights	ChemBioChem	2009	634	0
DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV	Angewandte Chemie	2009	650	0
Imaging of mRNA in Live Cells Using Nucleic Acid-Templated Reduction of Azidorhodamine Probes	Journal of the American Chemical Society	2009	597	4
High-Throughput Synthesis of Natural Products	The Power of Functional Resins in Organic Synthesis	2009	773	0
Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents	Chemical communications	2008	609	0
Expanding the Scope and Orthogonality of PNA Synthesis	European journal of organic chemistry	2008	622	5
Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor	Angewandte Chemie	2008	675	0
Resorcylic acid lactones: A pluripotent scaffold with therapeutic potential	Comptes rendus. Chimie	2008	679	0
Chemical Technologies: Probing Biology with Small Molecules	Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine	2008	755	0
Nucleic acid encoding to program self-assembly in chemical biology	Chemical Society reviews	2008	596	0
Expanding the scope of PNA-encoded libraries: divergent synthesis of libraries targeting cysteine, serine and metallo-proteases as well as tyrosine phosphatases	Tetrahedron	2007	906	5
Modular Synthesis of Radicicol A and Related Resorcylic Acid Lactones, Potent Kinase Inhibitors	Angewandte Chemie	2007	674	0
Probing Biology with Small Molecule Microarrays (SMM)	Combinatorial Chemistry on Solid Supports	2007	675	0
A Highly Efficient Azide-Based Protecting Group for Amines and Alcohols	Organic letters	2007	673	0
IPy₂BF₄-Mediated Glycosylation and Glycosyl Fluoride Formation	European journal of organic chemistry	2007	697	0
Chemistry and biology of resorcylic acid lactones	Chemical communications	2007	556	2
Fluorescence-based detection of single nucleotide permutation in DNA via catalytically templated reaction	Chemical communications	2007	606	3
Modular Asymmetric Synthesis of Aigialomycin D, a Kinase-Inhibitory Scaffold	Angewandte Chemie	2006	545	0
Self-Assembled Small-Molecule Microarrays for Protease Screening and Profiling	ChemBioChem	2006	644	0
Diversity-Oriented Synthesis of Pochonins and Biological Evaluation against a Panel of Kinases	Chemistry	2006	550	2
Microarray-based functional protein profiling using peptide nucleic acid-encoded libraries	Expert review of proteomics	2005	783	0
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitors Based on Conformational Analysis of Radicicol and Its Analogues	Journal of the American Chemical Society	2005	556	0
PNA Encoding (PNA=peptide nucleic acid): From Solution-Based Libraries to Organized Microarrays	Chemistry	2005	646	0
Concise Synthesis of Pochonin A, an HSP90 Inhibitor	Organic letters	2005	578	0
Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C	Chemistry	2005	621	0
Activity Profile of Dust Mite Allergen Extract Using Substrate Libraries and Functional Proteomic Microarrays	Chemistry & biology	2004	628	2
Development of a Functionalized Xenon Biosensor	Journal of the American Chemical Society	2004	635	0
Synthesis of a PNA-encoded cysteine protease inhibitor library	Tetrahedron	2004	702	3
Modular Asymmetric Synthesis of Pochonin C	Angewandte Chemie	2004	646	0
PNA-Encoded Protease Substrate Microarrays	Chemistry & biology	2004	552	0
Applications of laser-polarized ¹²⁹Xe to biomolecular assays	Magnetic resonance imaging	2003	581	0
Azidopeptide Nucleic Acid. An Alternative Strategy for Solid-Phase Peptide Nucleic Acid (PNA) Synthesis	Organic letters	2003	627	2
Novel strategies for the solid phase synthesis of substituted indolines and indoles	Bioorganic & medicinal chemistry	2003	572	0
Profiling protein function with small molecule microarrays	Proceedings of the National Academy of Sciences of the United States of America	2002	631	0
From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling	Angewandte Chemie	2001	632	0
Synthesis and Biological Evaluation of Vancomycin Dimers with Potent Activity against Vancomycin-Resistant Bacteria: Target-Accelerated Combinatorial Synthesis	Chemistry	2001	649	2
A New Photolabile Linker for the Photoactivation of Carboxyl Groups	Synlett	2001	698	0
Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs	Anticancer Agents: Frontiers in Cancer Chemotherapy	2001	632	0
Solid- and Solution-Phase Synthesis of Vancomycin and Vancomycin Analogues with Activity against Vancomycin-Resistant Bacteria	Chemistry	2001	650	0
Total Synthesis of 16-Desmethylepothilone B, Epothilone B ₁₀, Epothilone F, and Related Side Chain Modified Epothilone B Analogues	Chemistry	2000	612	0
New Selenium-Based Safety-Catch Linkers: Solid-Phase Semisynthesis of Vancomycin	Angewandte Chemie	2000	621	0
Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria	Angewandte Chemie	2000	615	0
The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century	Angewandte Chemie	2000	1,020	2
Total Synthesis of Vancomycin	Angewandte Chemie	1999	750	0
Total Synthesis of Vancomycin—Part 4: Attachment of the Sugar Moieties and Completion of the Synthesis	Chemistry	1999	854	0
Total Synthesis and Chemical Biology of the Sarcodictyins	Chemical and pharmaceutical bulletin	1999	606	429
Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics	Angewandte Chemie	1999	759	0
Synthesis of the macrocyclic core of sanglifehrin A	Chemical communications	1999	567	0
Solid and Solution Phase Synthesis and Biological Evaluation of Combinatorial Sarcodictyin Libraries	Journal of the American Chemical Society	1998	598	0
Polymer-supported selenium reagents for organic synthesis	Chemical communications	1998	626	0
Solid-Phase Synthesis of Macrocyclic Systems by a Cyclorelease Strategy: Application of the Stille Coupling to a Synthesis of (S)-Zearalenone	Angewandte Chemie	1998	618	0
Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide	Angewandte Chemie	1998	581	0
The Art and Science of Organic and Natural Products Synthesis	Journal of chemical education	1998	608	0
Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library	Journal of the American Chemical Society	1998	695	0
Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells	Angewandte Chemie	1997	654	0
A General and Highly Efficient Solid Phase Synthesis of Oligosaccharides. Total Synthesis of a Heptasaccharide Phytoalexin Elicitor (HPE)	Journal of the American Chemical Society	1997	675	0
Synthesis of epothilones A and B in solid and solution phase	Nature	1997	668	3
Versatile Method for Parallel Synthesis	Methods in molecular and cellular biology	1996	564	0
Multiple simultaneous synthesis of phenolic libraries	Molecular diversity	1995	640	0

Self-assembled proteomimetic (SAP) with antibody-like binding from short PNA–peptide conjugates

Proceedings of the National Academy of Sciences of the United States of America

2025

98

184

Photocatalytic Microenvironment Proteomics of Thiol-Mediated Uptake

JACS Au

2025

19

22

Sequencing of _D/_L -DNA and XNA by Templated-Synthesis

Journal of the American Chemical Society

2025

32

35

DNA-Drug Conjugates (DDCs) for computed delivery

2025

40

34

Red‐Shifted Bioluminescence Using Substrate‐Fluorophore Conjugates

Helvetica chimica acta

2025

37

0

Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability

Nature communications

2025

167

52

PTPRZ1-targeting RNA CAR T cells exert antigen-specific and bystander antitumor activity in glioblastoma

Cancer immunology research

2024

302

301

Total Synthesis of Tagitinins, Goyazensolide and Related Furanoheliangolides and their Covalent Interaction with Importin‐5 (IPO5)

Helvetica chimica acta

2024

52

47

Bright Red Bioluminescence from Semisynthetic NanoLuc (sNLuc)

ACS chemical biology

2024

95

64

Reversible Anticoagulants: Inspired by Nature, Designed for Safety

TheScienceBreaker

2024

25

26

Translation of Deoxyribonucleic Acid into Synthetic Alpha Helical Peptides for Darwinian Evolution

JACS Au

2024

29

28

Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains

ACS chemical biology

2024

26

44

Impact of charges on the hybridization kinetics and thermal stability of PNA duplexes

Organic & biomolecular chemistry

2024

62

24

Development of supramolecular anticoagulants with on-demand reversibility

Nature biotechnology

2024

201

278

Supernatural: Artificial Nucleobases and Backbones to Program Hybridization-Based Assemblies and Circuits

Bioconjugate chemistry

2023

200

113

Rapid Synthesis of Propargyl‐γ‐Modified Peptide Nucleic Acid Monomers for Late‐Stage Functionalization of Oligomers

Helvetica chimica acta

2023

120

57

Two‐Helix Supramolecular Proteomimetic Binders Assembled via PNA‐Assisted Disulfide Crosslinking

ChemBioChem

2023

305

0

PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma

2023

244

548

Pseudo-Complementary G:C Base Pair for Mixed Sequence dsDNA Invasion and Its Applications in Diagnostics (SARS-CoV-2 Detection)

JACS Au

2023

125

185

SCS Spring Meeting 2022 on Biosupramolecular Chemistry

Chimia : Frontiers in Ultrafast Spectroscopy and Dynamics

2022

247

140

Biosupramolecular networks: Taking inspiration from nature to create powerful synthetic platforms

Current opinion in chemical biology

2022

308

314

A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules

Nature chemistry

2022

325

0

Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization

Angewandte Chemie. International edition in English

2022

284

237

DNA‐Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution

Angewandte Chemie

2022

178

434

Withaferin A, a polyfunctional pharmacophore that includes covalent engagement of IPO5, is an inhibitor of influenza A replication

Bioorganic & medicinal chemistry

2022

273

172

Synthesis of Protein-Oligonucleotide Conjugates

Biomolecules

2022

59

Combining recombinase polymerase amplification and DNA-templated reaction for SARS-CoV-2 sensing with dual fluorescence and lateral flow assay output

Biopolymers

2022

366

166

Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond

Frontiers in oncology

2021

81

48

Kinesin-1 activity recorded in living cells with a precipitating dye

Nature Communications

2021

533

209

Suprastapled Peptides: Hybridization-Enhanced Peptide Ligation and Enforced α-Helical Conformation for Affinity Selection of Combinatorial Libraries

Journal of the American Chemical Society

2021

306

572

SARS-COV2- infection as a trigger of humoral response against apolipoprotein A-1

EAS Congress 2021

2021

384

38

Luciferase Controlled Protein Interactions

Journal of the American Chemical Society

2021

337

351

Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2

Chimia

2021

301

238

Total Syntheses of Paraconic Acids and 1,10-seco-Guaianolides via a Barbier Allylation/Translactonization Cascade of 3-(Bromomethyl)-2(5H)-furanone

Organic Letters

2021

551

235

Photocatalysis in Chemical Biology: Extending the Scope of Optochemical Control and Towards New Frontiers in Semisynthetic Bioconjugates and Biocatalysis

Helvetica chimica acta

2021

319

348

Oligonucleotide Phosphorothioates Enter Cells by Thiol‐Mediated Uptake

Angewandte Chemie: International Edition

2021

304

826

Biosupramolecular Systems: Integrating Cues into Responses

Journal of the American Chemical Society

2021

440

285

A minimal hybridization chain reaction (HCR) system using peptide nucleic acids

Chemical Science

2021

271

226

Synthesis of α-exo-Methylene-γ-butyrolactones: Recent Developments and Applications in Natural Product Synthesis

Synthesis

2021

435

551

Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides

ACS Central Science

2021

358

470

SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1

European Journal of Clinical Investigation

2021

424

271

Flipper Probes for the Community

Chimia

2021

468

287

Dual Bcl-XL /Bcl-2 inhibitors discovered from DNA-encoded libraries using a fragment pairing strategy

Bioorganic & Medicinal Chemistry

2021

253

149

Probing for Thiol-Mediated Uptake into Bacteria

ChemBioChem

2020

472

493

Sense-and-Release Logic-Gated Molecular Network Responding to Dimeric Cell Surface Proteins

Journal of the American Chemical Society

2020

397

301

PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule Libraries

Peptide Nucleic Acids: Methods and Protocols

2020

499

1

Smartphone DNA or RNA Sensing Using Semisynthetic Luciferase-Based Logic Device

ACS Sensors

2020

421

632

Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma

PLOS ONE

2020

470

354

Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9

Molecular and Cellular Proteomics

2020

485

283

The RB596 antibody recognizes a linear epitope from the spike S protein from SARS-CoV-2

Antibody Reports

2020

237

86

Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90

Frontiers in oncology

2020

141

73

Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks

Journal of the American Chemical Society

2020

491

4

Enhanced SNP-sensing using DNA-templated reactions through confined hybridization of minimal substrates (CHOMS)

Chemical Science

2020

372

253

Kilian Muñiz (1970–2020)

Angewandte Chemie: International Edition

2020

403

0

Caprin‐1 Promotes Cellular Uptake of Nucleic Acids with Backbone and Sequence Discrimination

Helvetica Chimica Acta

2020

501

328

Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functions

ACS Chemical Biology

2020

525

522

PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins

Bioorganic & Medicinal Chemistry

2020

418

3

Luciferase-Induced Photouncaging: Bioluminolysis

Angewandte Chemie: International Edition

2019

516

626

Coupling of DNA Circuit and Templated Reactions for Quadratic Amplification and Release of Functional Molecules

Journal of the American Chemical Society

2019

477

446

Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures

Chemical Science

2019

516

306

Sphingolipids and membrane targets for therapeutics

Current Opinion in Chemical Biology

2019

561

3

Turn On of a Ruthenium(II) Photocatalyst by DNA-Templated Ligation

Chemistry - A European Journal

2019

599

580

Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics

Current Opinion in Chemical Biology

2019

504

968

Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology

Chemistry - A European Journal

2019

592

652

Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function

eLife

2018

585

767

Synthesis of deoxyelephantopin analogues

Journal of Antibiotics

2018

537

310

Double-Stranded RNA-Specific Templated Reaction with Triplex Forming PNA

Helvetica Chimica Acta

2018

596

1,170

Luciferase-induced photoreductive uncaging of small-molecule effectors

Nature Communications

2018

626

337

Editorial overview: Synthetic biomolecules

Current Opinion in Chemical Biology

2018

472

0

Peptide nucleic acid-templated selenocystine–selenoester ligation enables rapid miRNA detection

Chemical Science

2018

588

296

Biography of Professor Nicolaou: a journey to the extremes of molecular complexity

Journal of Antibiotics

2018

529

2

Ruthenium-based Photocatalysis in Templated Reactions

Chimia

2018

589

330

Accelerating Turnover Frequency in Nucleic Acid Templated Reactions

Bioconjugate Chemistry

2018

549

404

Rapid and scalable synthesis of chiral bromolactones as precursors to α-exo-methylene-γ-butyrolactone-containing sesquiterpene lactones

Tetrahedron

2018

513

631

Bioorthogonal Chemistry

Chimia

2018

443

383

Covalent inhibitors : an opportunity for rational target selectivity

Current opinion in chemical biology

2017

626

551

Kinase-templated abiotic reaction

Chemical science

2017

560

255

Following the Lead from Nature with Covalent Inhibitors

Chimia

2017

528

0

Dynamic cooperative glycan assembly blocks the binding of bacterial lectins to epithelial cells

Angewandte Chemie

2017

587

250

Critical Analysis of Rate Constants and Turnover Frequency in Nucleic Acid-Templated Reactions: Reaching Terminal Velocity

Journal of the American Chemical Society

2017

858

695

Facile access to modified and functionalized PNAs through Ugi-based solid phase oligomerization

Bioorganic & Medicinal Chemistry

2017

584

915

Rapid and Scalable Synthesis of cis-Fused Guaiane-Type Sesquiterpenes

European journal of organic chemistry

2016

633

3

Activation of Cell-Penetrating Peptides with Ionpair−π Interactions and Fluorophiles

Journal of the American Chemical Society

2016

737

473

A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer

Oncotarget

2016

576

0

Allosterically Regulated Phosphatase Activity from Peptide-PNA Conjugates Folded Through Hybridization

Angewandte Chemie

2016

621

9

Duplex formation and secondary structure of γ-PNA observed by NMR and CD

Biophysical chemistry

2016

816

2

Divergent synthesis and identification of the cellular targets of deoxyelephantopins

Nature communications

2016

610

405

One-Step Derivatization of Reducing Oligosaccharides for Rapid and Live-Cell Compatible Chelation-Assisted CuAAC Conjugation

ChemBioChem

2016

669

5

Nucleic Acid Templated Chemical Reaction in a Live Vertebrate

ACS central science

2016

690

304

High Spatial Resolution Imaging of Endogenous Hydrogen Peroxide in Living Cells by Solid-State Fluorescence

ChemBioChem

2016

551

0

Novel PTP1B inhibitors identified by DNA display of fragment pairs

Bioorganic & medicinal chemistry letters

2016

691

10

Screening for covalent inhibitors using DNA-display of small molecule libraries functionalized with cysteine reactive moieties

MedChemComm

2016

638

12

Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules

Angewandte Chemie

2015

777

13

HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas

Cancer letters

2015

657

2

PNA-encoded chemical libraries

Current opinion in chemical biology

2015

663

12

Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne

Bioconjugate chemistry

2015

636

6

DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules

Chemical science

2015

799

12

DNA display of glycoconjugates to emulate oligomeric interactions of glycans

Beilstein journal of organic chemistry

2015

657

325

In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis

Chemical communications

2015

689

8

PNA as a Biosupramolecular Tag for Programmable Assemblies and Reactions

Accounts of chemical research

2015

688

11

Rapid miRNA Imaging in Cells Using Fluorogenic Templated Staudinger Reaction Between PNA-Based Probes

Peptide Nucleic Acids : Methods and Protocols

2014

758

0

Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway

Organic & biomolecular chemistry

2014

765

14

Assembly of PNA-Tagged Small Molecules, Peptides, and Carbohydrates onto DNA Templates: Programming the Combinatorial Pairing and Inter-ligand Distance

Peptide Nucleic Acids : Methods and Protocols

2014

728

0

PNA-Encoded Synthesis (PES) of a 10 000-Member Hetero-Glycoconjugate Library and Microarray Analysis of Diverse Lectins

ChemBioChem

2014

632

4

A LecA Ligand Identified from a Galactoside-Conjugate Array Inhibits Host Cell Invasion by Pseudomonas aeruginosa

Angewandte Chemie

2014

581

5

Reactions Templated by Nucleic Acids: More Ways to Translate Oligonucleotide-Based Instructions into Emerging Function

Angewandte Chemie

2013

708

13

Self-Assembled Antibody Multimers through Peptide Nucleic Acid Conjugation

Journal of the American Chemical Society

2013

655

8

Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis

European journal of organic chemistry

2013

676

6

Selective affinity-based probe for oncogenic kinases suitable for live cell imaging

Chemical science

2013

724

9

Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates

Chemical communications

2013

679

4

Nucleic Acid-programmed Assemblies: Translating Instruction into Function in Chemical Biology

Chimia

2013

692

621

Picture Perfect: DNA-Templated Photoaffinity Labeling

ChemBioChem

2013

701

6

Detection of miRNA in Live Cells by Using Templated Ru^II-Catalyzed Unmasking of a Fluorophore

Chemistry

2013

725

8

Nucleic Acid-tagged Peptides: Encoding Libraries and Controlling Dimerization and Conformation

Chimia

2013

686

4

DNA as a Platform to Program Assemblies with Emerging Functions in Chemical Biology

Israel Journal of Chemistry

2013

659

0

DNA display of PNA-tagged ligands: A versatile strategy to screen libraries and control geometry of multidentate ligands

Artificial DNA, PNA & XNA

2012

615

399

Diversity-Oriented Synthesis of Diverse Polycyclic Scaffolds Inspired by the Logic of Sesquiterpene Lactones Biosynthesis

Angewandte Chemie

2012

671

4

Expanding the Scope of PNA-Encoded Synthesis (PES): Mtt-Protected PNA Fully Orthogonal to Fmoc Chemistry and a Broad Array of Robust Diversity-Generating Reactions

Chemistry

2012

730

9

Asymmetric Synthesis of Pochonin E and F, Revision of Their Proposed Structure, and Their Conversion to Potent Hsp90 Inhibitors

Chemistry

2012

673

3

Photoreductive Uncaging of Fluorophore in Response to Protein Oligomers by Templated Reaction in Vitro and in Cellulo

Journal of the American Chemical Society

2012

650

8

Polyubiquitination of Transforming Growth Factor β(TGFβ)-associated Kinase 1 Mediates Nuclear Factor-κB Activation in Response to Different Inflammatory Stimuli

The Journal of biological chemistry

2012

665

0

Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries

Organic & biomolecular chemistry

2012

665

5

Nucleic Acid Templated Uncaging of Fluorophores Using Ru-Catalyzed Photoreduction with Visible Light

Organic letters

2012

670

7

Synthesis of deguelin–biotin conjugates and investigation into deguelin's interactions

Bioorganic & medicinal chemistry

2012

667

0

Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells

Chemical communications

2011

591

694

Rapid fluorescence imaging of miRNAs in human cells using templated Staudinger reaction

Chemical science

2011

661

1,010

Translating instructions into function by nucleic acid programmed self-assembly

L'Actualité chimique

2011

679

0

Cysteine Mapping in Conformationally Distinct Kinase Nucleotide Binding Sites: Application to the Design of Selective Covalent Inhibitors

Journal of medicinal chemistry

2011

642

2

DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker

Chemical communications

2011

608

8

Combinatorial Self-Assembly of Glycan Fragments into Microarrays

ChemBioChem

2011

654

2

DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles

Chemical science

2011

683

5

Nucleic Acid-Templated Energy Transfer Leading to a Photorelease Reaction and its Application to a System Displaying a Nonlinear Response

Journal of the American Chemical Society

2011

666

6

In Vivo Efficacy of Natural Product-Inspired Irreversible Kinase Inhibitors

ChemBioChem

2010

610

0

Ligand dimerization programmed by hybridization to study multimeric ligand–receptor interactions

Chemical communications

2010

583

0

The Novel Hsp90 Inhibitor NXD30001 Induces Tumor Regression in a Genetically Engineered Mouse Model of Glioblastoma Multiforme

Molecular cancer therapeutics

2010

632

0

Clickable peptide nucleic acids (cPNA) with tunable affinity

Chemical communications

2010

614

4

Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL

ChemMedChem

2010

550

0

Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation

Proteomics

2010

608

0

Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular Process

The Journal of biological chemistry

2010

548

0

Metathesis Reactions in Solid-Phase Organic Synthesis

Metathesis in Natural Product Synthesis: Strategies, Substrates and Catalysts

2010

691

0

Concise Modular Asymmetric Synthesis of Deguelin, Tephrosin and Investigation into Their Mode of Action

Chemistry

2010

637

0

Selection of bead-displayed, PNA-encoded chemicals

JMR. Journal of molecular recognition

2010

624

0

The molecular chaperone Hsp90alpha is required for meiotic progression of spermatocytes beyond pachytene in the mouse

PloS one

2010

769

472

Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases

Chemistry

2009

542

0

Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin

Chemistry

2009

631

0

Self-Assembly of PNA-Encoded Peptides into Microarrays

Peptide Microarrays: Methods and Protocols

2009

773

0

Synthesis of pochoxime prodrugs as potent HSP90 inhibitors

Bioorganic & medicinal chemistry letters

2009

557

0

Hsp90 Inhibition with Resorcylic Acid Lactones (RALs)

Current topics in medicinal chemistry

2009

732

0

The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR ¹⁵N chemical shifts

Biophysical chemistry

2009

675

0

Inhibition of HSP90 with Pochoximes: SAR and Structure-Based Insights

ChemBioChem

2009

634

0

DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

Angewandte Chemie

2009

650

0

Imaging of mRNA in Live Cells Using Nucleic Acid-Templated Reduction of Azidorhodamine Probes

Journal of the American Chemical Society

2009

597

4

High-Throughput Synthesis of Natural Products

The Power of Functional Resins in Organic Synthesis

2009

773

0

Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents

Chemical communications

2008

609

0

Expanding the Scope and Orthogonality of PNA Synthesis

European journal of organic chemistry

2008

622

5

Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor

Angewandte Chemie

2008

675

0

Resorcylic acid lactones: A pluripotent scaffold with therapeutic potential

Comptes rendus. Chimie

2008

679

0

Chemical Technologies: Probing Biology with Small Molecules

Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine

2008

755

0

Nucleic acid encoding to program self-assembly in chemical biology

Chemical Society reviews

2008

596

0

Expanding the scope of PNA-encoded libraries: divergent synthesis of libraries targeting cysteine, serine and metallo-proteases as well as tyrosine phosphatases

Tetrahedron

2007

906

5

Modular Synthesis of Radicicol A and Related Resorcylic Acid Lactones, Potent Kinase Inhibitors

Angewandte Chemie

2007

674

0

Probing Biology with Small Molecule Microarrays (SMM)

Combinatorial Chemistry on Solid Supports

2007

675

0

A Highly Efficient Azide-Based Protecting Group for Amines and Alcohols

Organic letters

2007

673

0

IPy₂BF₄-Mediated Glycosylation and Glycosyl Fluoride Formation

European journal of organic chemistry

2007

697

0

Chemistry and biology of resorcylic acid lactones

Chemical communications

2007

556

2

Fluorescence-based detection of single nucleotide permutation in DNA via catalytically templated reaction

Chemical communications

2007

606

3

Modular Asymmetric Synthesis of Aigialomycin D, a Kinase-Inhibitory Scaffold

Angewandte Chemie

2006

545

0

Self-Assembled Small-Molecule Microarrays for Protease Screening and Profiling

ChemBioChem

2006

644

0

Diversity-Oriented Synthesis of Pochonins and Biological Evaluation against a Panel of Kinases

Chemistry

2006

550

2

Microarray-based functional protein profiling using peptide nucleic acid-encoded libraries

Expert review of proteomics

2005

783

0

Design, Synthesis, and Biological Evaluation of HSP90 Inhibitors Based on Conformational Analysis of Radicicol and Its Analogues

Journal of the American Chemical Society

2005

556

0

PNA Encoding (PNA=peptide nucleic acid): From Solution-Based Libraries to Organized Microarrays

Chemistry

2005

646

0

Concise Synthesis of Pochonin A, an HSP90 Inhibitor

Organic letters

2005

578

0

Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C

Chemistry

2005

621

0

Activity Profile of Dust Mite Allergen Extract Using Substrate Libraries and Functional Proteomic Microarrays

Chemistry & biology

2004

628

2

Development of a Functionalized Xenon Biosensor

Journal of the American Chemical Society

2004

635

0

Synthesis of a PNA-encoded cysteine protease inhibitor library

Tetrahedron

2004

702

3

Modular Asymmetric Synthesis of Pochonin C

Angewandte Chemie

2004

646

0

PNA-Encoded Protease Substrate Microarrays

Chemistry & biology

2004

552

0

Applications of laser-polarized ¹²⁹Xe to biomolecular assays

Magnetic resonance imaging

2003

581

0

Azidopeptide Nucleic Acid. An Alternative Strategy for Solid-Phase Peptide Nucleic Acid (PNA) Synthesis

Organic letters

2003

627

2

Novel strategies for the solid phase synthesis of substituted indolines and indoles

Bioorganic & medicinal chemistry

2003

572

0

Profiling protein function with small molecule microarrays

Proceedings of the National Academy of Sciences of the United States of America

2002

631

0

From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling

Angewandte Chemie

2001

632

0

Synthesis and Biological Evaluation of Vancomycin Dimers with Potent Activity against Vancomycin-Resistant Bacteria: Target-Accelerated Combinatorial Synthesis

Chemistry

2001

649

2

A New Photolabile Linker for the Photoactivation of Carboxyl Groups

Synlett

2001

698

0

Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs

Anticancer Agents: Frontiers in Cancer Chemotherapy

2001

632

0

Solid- and Solution-Phase Synthesis of Vancomycin and Vancomycin Analogues with Activity against Vancomycin-Resistant Bacteria

Chemistry

2001

650

0

Total Synthesis of 16-Desmethylepothilone B, Epothilone B ₁₀, Epothilone F, and Related Side Chain Modified Epothilone B Analogues

Chemistry

2000

612

0

New Selenium-Based Safety-Catch Linkers: Solid-Phase Semisynthesis of Vancomycin

Angewandte Chemie

2000

621

0

Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

Angewandte Chemie

2000

615

0

The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

Angewandte Chemie

2000

1,020

2

Total Synthesis of Vancomycin

Angewandte Chemie

1999

750

0

Total Synthesis of Vancomycin—Part 4: Attachment of the Sugar Moieties and Completion of the Synthesis

Chemistry

1999

854

0

Total Synthesis and Chemical Biology of the Sarcodictyins

Chemical and pharmaceutical bulletin

1999

606

429

Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics

Angewandte Chemie

1999

759

0

Synthesis of the macrocyclic core of sanglifehrin A

Chemical communications

1999

567

0

Solid and Solution Phase Synthesis and Biological Evaluation of Combinatorial Sarcodictyin Libraries

Journal of the American Chemical Society

1998

598

0

Polymer-supported selenium reagents for organic synthesis

Chemical communications

1998

626

0

Solid-Phase Synthesis of Macrocyclic Systems by a Cyclorelease Strategy: Application of the Stille Coupling to a Synthesis of (S)-Zearalenone

Angewandte Chemie

1998

618

0

Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

Angewandte Chemie

1998

581

0

The Art and Science of Organic and Natural Products Synthesis

Journal of chemical education

1998

608

0

Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library

Journal of the American Chemical Society

1998

695

0

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

Angewandte Chemie

1997

654

0

A General and Highly Efficient Solid Phase Synthesis of Oligosaccharides. Total Synthesis of a Heptasaccharide Phytoalexin Elicitor (HPE)

Journal of the American Chemical Society

1997

675

0

Synthesis of epothilones A and B in solid and solution phase

Nature

1997

668

3

Versatile Method for Parallel Synthesis

Methods in molecular and cellular biology

1996

564

0

Multiple simultaneous synthesis of phenolic libraries

Molecular diversity

1995

640

0

Affiliation entities

Research groups

Archive ouverte UNIGE

Winssinger, Nicolas

account_balance Affiliation entities

Research groups

Affiliation entities