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Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C

Barluenga, Sofia
Moulin, Emilie
Lopez, Pilar
Published in Chemistry - A European Journal. 2005, vol. 11, no. 17, p. 4935-4952
Abstract A modular synthesis for pochonin C and radicicol is reported. The two natural products were prepared in seven and eight steps, respectively, from three readily available fragments. Alternative syntheses of these compounds were achieved using a combination of polymer-bound reagents and solid phase reactions. The conformation of the two natural products was studied and compared by using 2D NMR spectroscopy.
Keywords metathesisnatural productssolid-phase synthesistotal synthesis
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BARLUENGA, Sofia et al. Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C. In: Chemistry - A European Journal, 2005, vol. 11, n° 17, p. 4935-4952.

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Deposited on : 2012-12-12

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