Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C

Barluenga, Sofia; Moulin, Emilie; Lopez, Pilar; Winssinger, Nicolas

doi:10.1002/chem.200500160

Scientific article

English

Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C

Contributors

Barluenga, Sofia; Moulin, Emilie; Lopez, Pilar; Winssinger, Nicolas

Published in

Chemistry, vol. 11, no. 17, p. 4935-4952

Publication date

2005

Abstract

A modular synthesis for pochonin C and radicicol is reported. The two natural products were prepared in seven and eight steps, respectively, from three readily available fragments. Alternative syntheses of these compounds were achieved using a combination of polymer-bound reagents and solid phase reactions. The conformation of the two natural products was studied and compared by using 2D NMR spectroscopy.

Keywords

metathesis
natural products
solid-phase synthesis
total synthesis

UNIGE affiliation entities

Not a UNIGE publication

Citation (ISO format)

BARLUENGA, Sofia et al. Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C. In: Chemistry, 2005, vol. 11, n° 17, p. 4935–4952. doi: 10.1002/chem.200500160

Article (Published version)

Identifiers

PID : unige:24522
DOI : 10.1002/chem.200500160

Journal ISSN

0947-6539

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Creation

11/12/2012 17:01:00

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11/12/2012 17:01:00

Update

13/10/2025 23:53:13

Status update

14/03/2023 17:47:13

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01/07/2026 06:09:16

Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C

Contributors

Published in

Publication date

Abstract

Keywords

UNIGE affiliation entities

Citation (ISO format)

Main files (1)

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Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation