The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

Nicolaou, K. C.; Vourloumis, Dionisios; Winssinger, Nicolas; Baran, Phil S.

doi:10.1002/(SICI)1521-3773(20000103)39:1<44::AID-ANIE44>3.0.CO;2-L

Scientific article

English

The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

ContributorsNicolaou, K. C.; Vourloumis, Dionisios; Winssinger, Nicolas; Baran, Phil S.

Published inAngewandte Chemie, vol. 39, no. 1, p. 44-122

Publication date2000

Abstract

A new millenium has begun—grounds enough to question the present state of the total synthesis of natural products. In this review we answer this question by tracing the evolution of this fine art and science from its birth to the present time. This retrospective on total synthesis should serve to demonstrate how far we have come, yet show that the science of total synthesis is still in its infancy.

Keywords

Drug research
Natural products
Synthetic methods
Total synthesis

Affiliation Not a UNIGE publication

Citation (ISO format)

NICOLAOU, K. C. et al. The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century. In: Angewandte Chemie, 2000, vol. 39, n° 1, p. 44–122. doi: 10.1002/(SICI)1521-3773(20000103)39:1<44::AID-ANIE44>3.0.CO;2-L

Article (Published version)

Identifiers

PID : unige:24513
DOI : 10.1002/(SICI)1521-3773(20000103)39:1<44::AID-ANIE44>3.0.CO;2-L

ISSN of the journal1433-7851

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The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

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