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Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates

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Published in Chemical Communications. 2013, vol. 49, no. 69, p. 7608-7610
Abstract An expedient and simple protocol to access S-linked glycopeptides by Fmoc SPPS using unprotected carbohydrates is reported. The utility of the method was demonstrated with the solid phase synthesis of a MUC1 fragment (20 mer) containing two glycosylation sites that were substituted with S-linked glycans.
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Other version: http://xlink.rsc.org/?DOI=c3cc43458c
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NOVOA, Alexandre et al. Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates. In: Chemical Communications, 2013, vol. 49, n° 69, p. 7608-7610. https://archive-ouverte.unige.ch/unige:29565

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Deposited on : 2013-09-04

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