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Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates

Publié dansChemical communications, vol. 49, no. 69, p. 7608-7610
Date de publication2013
Résumé

An expedient and simple protocol to access S-linked glycopeptides by Fmoc SPPS using unprotected carbohydrates is reported. The utility of the method was demonstrated with the solid phase synthesis of a MUC1 fragment (20 mer) containing two glycosylation sites that were substituted with S-linked glycans.

Citation (format ISO)
NOVOA, Alexandre et al. Solid phase synthesis of glycopeptides using Shoda’s activation of unprotected carbohydrates. In: Chemical communications, 2013, vol. 49, n° 69, p. 7608–7610. doi: 10.1039/c3cc43458c
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Identifiants
ISSN du journal1359-7345
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Informations techniques

Création02/09/2013 16:51:00
Première validation02/09/2013 16:51:00
Heure de mise à jour14/03/2023 20:23:53
Changement de statut14/03/2023 20:23:53
Dernière indexation16/01/2024 02:06:21
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