en
Scientific article
English

Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates

Published inChemical communications, vol. 49, no. 69, p. 7608-7610
Publication date2013
Abstract

An expedient and simple protocol to access S-linked glycopeptides by Fmoc SPPS using unprotected carbohydrates is reported. The utility of the method was demonstrated with the solid phase synthesis of a MUC1 fragment (20 mer) containing two glycosylation sites that were substituted with S-linked glycans.

Citation (ISO format)
NOVOA, Alexandre et al. Solid phase synthesis of glycopeptides using Shoda’s activation of unprotected carbohydrates. In: Chemical communications, 2013, vol. 49, n° 69, p. 7608–7610. doi: 10.1039/c3cc43458c
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ISSN of the journal1359-7345
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Creation09/02/2013 4:51:00 PM
First validation09/02/2013 4:51:00 PM
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