A New Photolabile Linker for the Photoactivation of Carboxyl Groups

Nicolaou, K. C.; Safina, Brian S.; Winssinger, Nicolas

doi:10.1055/s-2001-14661

Scientific article

English

A New Photolabile Linker for the Photoactivation of Carboxyl Groups

ContributorsNicolaou, K. C.; Safina, Brian S.; Winssinger, Nicolas

Published inSynlett, vol. 2001, no. Special Issue, p. 0900-0903

Publication date2001

Abstract

A new photolabile linker enabling nucleophilic cleavage of a carboxyl functionality upon irradiation with UV light (> 290 nm) was developed. When the photocleavage is carried out in the presence of primary or secondary amines, amides are obtained in high yields and purities, while the intramolecular version of this reaction leads to heterocycles via a cyclorelease mechanism.

Affiliation Not a UNIGE publication

Citation (ISO format)

NICOLAOU, K. C., SAFINA, Brian S., WINSSINGER, Nicolas. A New Photolabile Linker for the Photoactivation of Carboxyl Groups. In: Synlett, 2001, vol. 2001, n° Special Issue, p. 0900–0903. doi: 10.1055/s-2001-14661

Article (Published version)

Identifiers

PID : unige:24510
DOI : 10.1055/s-2001-14661

ISSN of the journal0936-5214

543views

0downloads

Creation12/11/2012 4:19:00 PM

First validation12/11/2012 4:19:00 PM

Update time03/14/2023 5:47:07 PM

Status update03/14/2023 5:47:07 PM

Last indexation01/16/2024 12:38:26 AM

Archive ouverte UNIGE

A New Photolabile Linker for the Photoactivation of Carboxyl Groups

Technical informations