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Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis

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Published in European Journal of Organic Chemistry. 2013, vol. 2013, no. 20, p. 4195-4214
Abstract This microreview discusses recent efforts in chemical synthesis to design divergent pathways either to access diverse natural products from a common intermediate or to produce diverse libraries of compounds reminiscent of natural products. These efforts are generally based on the development and use of powerful complexity-generating reactions and cascade reactions. A panel of eighteen examples is used to illustrate different strategies.
Keywords Natural productsSynthesis designDivergent pathwaysMolecular diversityCascade reactions
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Other version: http://doi.wiley.com/10.1002/ejoc.201300201
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SERBA, Christelle, WINSSINGER, Nicolas. Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis. In: European Journal of Organic Chemistry, 2013, vol. 2013, n° 20, p. 4195-4214. https://archive-ouverte.unige.ch/unige:28922

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Deposited on : 2013-07-16

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