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Title

Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs

Authors
Nicolaou, K. C.
Published in Ojima, I.; Vite, G. D.; Altmann, K.-H. Anticancer Agents: Frontiers in Cancer Chemotherapy: American Chemical Society. 2001, p. 148-170
Collection ACS Symposium Series; 796
Abstract The epothilones and sarcodictyins have shown to be potent cytotoxic compounds with a Taxol™-like mode of action. The clinical importance of Taxol™ has stimulated intense research into finding compounds with prospective superior chemotherapeutic properties to Taxol™. We have developed enabling synthetic technologies for the construction of combinatorial libraries of these two potentially important chemotherapeutics, which led, in both cases to compounds with superior biological activity.
Identifiers
ISBN: 9780841237452
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WINSSINGER, Nicolas, NICOLAOU, K. C. Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs. In: Ojima, I.; Vite, G. D.; Altmann, K.-H. (Ed.). Anticancer Agents: Frontiers in Cancer Chemotherapy. [s.l.] : American Chemical Society, 2001. p. 148-170. (ACS Symposium Series; 796) https://archive-ouverte.unige.ch/unige:24744

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Deposited on : 2012-12-19

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