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Book Chapter
unige:24744 
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Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs |
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| Authors | ||
| Published in | Ojima, I.; Vite, G. D.; Altmann, K.-H. Anticancer Agents: Frontiers in Cancer Chemotherapy: American Chemical Society. 2001, p. 148-170 | |
| Collection |
ACS Symposium Series; 796 |
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| Abstract | The epothilones and sarcodictyins have shown to be potent cytotoxic compounds with a Taxol™-like mode of action. The clinical importance of Taxol™ has stimulated intense research into finding compounds with prospective superior chemotherapeutic properties to Taxol™. We have developed enabling synthetic technologies for the construction of combinatorial libraries of these two potentially important chemotherapeutics, which led, in both cases to compounds with superior biological activity. | |
| Identifiers | ISBN: 9780841237452 | |
| Full text | ||
| Citation (ISO format) | WINSSINGER, Nicolas, NICOLAOU, K. C. Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs. In: Ojima, I.; Vite, G. D.; Altmann, K.-H. (Ed.). Anticancer Agents: Frontiers in Cancer Chemotherapy. [s.l.] : American Chemical Society, 2001. p. 148-170. (ACS Symposium Series; 796) doi: 10.1021/bk-2001-0796.ch009 https://archive-ouverte.unige.ch/unige:24744 |
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