Book chapter
English

Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs

Published inOjima, I.; Vite, G. D.; Altmann, K.-H. (Ed.), Anticancer Agents: Frontiers in Cancer Chemotherapy, p. 148-170
PublisherAmerican Chemical Society
Collection
  • ACS Symposium Series; 796
Publication date2001
Abstract

The epothilones and sarcodictyins have shown to be potent cytotoxic compounds with a Taxol™-like mode of action. The clinical importance of Taxol™ has stimulated intense research into finding compounds with prospective superior chemotherapeutic properties to Taxol™. We have developed enabling synthetic technologies for the construction of combinatorial libraries of these two potentially important chemotherapeutics, which led, in both cases to compounds with superior biological activity.

Affiliation entities Not a UNIGE publication
Citation (ISO format)
WINSSINGER, Nicolas, NICOLAOU, K. C. Epothilones and Sarcodictyins: From Combinatorial Libraries to Designed Analogs. In: Anticancer Agents: Frontiers in Cancer Chemotherapy. Ojima, I.; Vite, G. D.; Altmann, K.-H. (Ed.). [s.l.] : American Chemical Society, 2001. p. 148–170. (ACS Symposium Series) doi: 10.1021/bk-2001-0796.ch009
Main files (1)
Book chapter (Published version)
accessLevelRestricted
Identifiers
ISBN9780841237452
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Update time14/03/2023 17:48:00
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