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Scientific article
English

Clickable peptide nucleic acids (cPNA) with tunable affinity

Published inChemical communications, vol. 46, no. 30, p. 5476-5478
Publication date2010
Abstract

Peptide nucleic acids (PNAs) are functional analogues of natural oligonucleotides. Herein, we report the synthesis of PNAs bearing a triazole in lieu of the amide bond assembled using a “click” cycloaddition, their hybridization properties as well as the DNA-templated coupling of the azide and alkyne PNA fragments.

Affiliation Not a UNIGE publication
Citation (ISO format)
CHOUIKHI, Dalila, BARLUENGA, Sofia, WINSSINGER, Nicolas. Clickable peptide nucleic acids (cPNA) with tunable affinity. In: Chemical communications, 2010, vol. 46, n° 30, p. 5476–5478. doi: 10.1039/c0cc01081b
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ISSN of the journal1359-7345
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Technical informations

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