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Title

Clickable peptide nucleic acids (cPNA) with tunable affinity

Authors
Chouikhi, Dalila
Barluenga, Sofia
Published in Chemical Communications. 2010, vol. 46, no. 30, p. 5476-5478
Abstract Peptide nucleic acids (PNAs) are functional analogues of natural oligonucleotides. Herein, we report the synthesis of PNAs bearing a triazole in lieu of the amide bond assembled using a “click” cycloaddition, their hybridization properties as well as the DNA-templated coupling of the azide and alkyne PNA fragments.
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Other version: http://xlink.rsc.org/?DOI=c0cc01081b
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CHOUIKHI, Dalila, BARLUENGA, Sofia, WINSSINGER, Nicolas. Clickable peptide nucleic acids (cPNA) with tunable affinity. In: Chemical Communications, 2010, vol. 46, n° 30, p. 5476-5478. https://archive-ouverte.unige.ch/unige:24704

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Deposited on : 2012-12-18

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