Synthesis of α-exo-Methylene-γ-butyrolactones: Recent Developments and Applications in Natural Product Synthesis

Liu, Weilong; Winssinger, Nicolas

doi:10.1055/a-1577-6085

Scientific article

English

Synthesis of α-exo-Methylene-γ-butyrolactones: Recent Developments and Applications in Natural Product Synthesis

ContributorsLiu, Weilong; Winssinger, Nicolas

Published inSynthesis, vol. 53, no. 21, p. 3977-3990

Publication date2021-09

First online date2021-08-03

Abstract

The α-exo-methylene-γ-butyrolactone moiety is present in a vast array of structurally diverse natural products and is often central to their biological activity. In this short review, we summarize new approaches to α-exo-methylene-γ-butyrolactones developed over the past decade as well as their applications in total synthesis.

Keywords

Natural products
Α-exo-methylene-γ-butyrolactones
Total synthesis
Sesquiterpene lactones
Lignans

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Research groups

Groupe Winssinger

Citation (ISO format)

LIU, Weilong, WINSSINGER, Nicolas. Synthesis of α-exo-Methylene-γ-butyrolactones: Recent Developments and Applications in Natural Product Synthesis. In: Synthesis, 2021, vol. 53, n° 21, p. 3977–3990. doi: 10.1055/a-1577-6085

Article (Published version)

Article (Accepted version)

Identifiers

PID : unige:155556
DOI : 10.1055/a-1577-6085

Commercial URLhttp://www.thieme-connect.de/DOI/DOI?10.1055/a-1577-6085

Journal ISSN0039-7881

264views

66downloads

Creation20/10/2021 10:30:00

First validation20/10/2021 10:30:00

Update time03/04/2024 13:24:44

Status update03/04/2024 13:24:44

Last indexation01/11/2024 00:26:08

Archive ouverte UNIGE

Synthesis of α-exo-Methylene-γ-butyrolactones: Recent Developments and Applications in Natural Product Synthesis

Technical informations