Picture Perfect: DNA-Templated Photoaffinity Labeling

Barluenga Badiola, Sofia; Winssinger, Nicolas

doi:10.1002/cbic.201300416

Scientific article

English

Picture Perfect: DNA-Templated Photoaffinity Labeling

ContributorsBarluenga Badiola, Sofia; Winssinger, Nicolas

Published inChemBioChem, vol. 14, no. 15, p. 1927-1928

Publication date2013

Abstract

Just so far apart and no further: Small molecules target ID by DNA tagging. Nucleic acid hybridization has been used to pair a photo-crosslinking group with a small molecule of interest. Following photoactivation, the protein(s) interacting with the small molecule are covalently linked to a nucleic acid tag.

Keywords

DNA
Photo-crosslinking
Small molecules

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

BARLUENGA BADIOLA, Sofia, WINSSINGER, Nicolas. Picture Perfect: DNA-Templated Photoaffinity Labeling. In: ChemBioChem, 2013, vol. 14, n° 15, p. 1927–1928. doi: 10.1002/cbic.201300416

Article (Published version)

Identifiers

PID : unige:30323
DOI : 10.1002/cbic.201300416

Journal ISSN1439-4227

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Creation08/10/2013 09:14:00

First validation08/10/2013 09:14:00

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Picture Perfect: DNA-Templated Photoaffinity Labeling

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