Scientific Article
previous document  unige:24696  next document
add to browser collection
Title

Combinatorial Self-Assembly of Glycan Fragments into Microarrays

Authors
Huang, Kuo-Ting
Gorska, Katarzyna
Alvarez, Susana
Barluenga, Sofia
Published in ChemBioChem. 2011, vol. 12, no. 1, p. 56-60
Abstract Complex glycan arrays: A general method for preparing thioglycosides from native oligosaccharides and coupling them to peptide nucleic acids (PNAs) is reported. An array of 625 glycans was assembled by hybridization of two PNA-encoded libraries of 25 glycan fragments. The cooperativity of the fragment for carbohydrate binding proteins was validated with lectins of known specificity.
Keywords glycan arraysmicroarraysPNAself-assemblythioglycosides
Identifiers
Full text
Article (Published version) (708 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://doi.wiley.com/10.1002/cbic.201000567
Citation
(ISO format)
HUANG, Kuo-Ting et al. Combinatorial Self-Assembly of Glycan Fragments into Microarrays. In: ChemBioChem, 2011, vol. 12, n° 1, p. 56-60. https://archive-ouverte.unige.ch/unige:24696

179 hits

2 downloads

Update

Deposited on : 2012-12-18

Export document
Format :
Citation style :