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Title

Synthesis of epothilones A and B in solid and solution phase

Authors
Nicolaou, K. C.
Pastor, J.
Ninkovic, S.
Sarabia, F.
He, Y.
Vourloumis, D.
Yang, Z.
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Published in Nature. 1997, vol. 387, no. 6630, p. 268-272
Abstract Epothilones A and B, two compounds that have been recently isolated from myxobacterium Sorangium cellulosum strain 90, have generated intense interest among chemists, biologists and clinicians owing to the structural complexity, unusual mechanism of interaction with microtubules and anticancer potential of these molecules.
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Article (Published version) (1 MB) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://www.nature.com/doifinder/10.1038/387268a0
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NICOLAOU, K. C. et al. Synthesis of epothilones A and B in solid and solution phase. In: Nature, 1997, vol. 387, n° 6630, p. 268-272. https://archive-ouverte.unige.ch/unige:24440

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Deposited on : 2012-12-12

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