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Concise Synthesis of Pochonin A, an HSP90 Inhibitor

Moulin, Emilie
Barluenga, Sofia
Published in Organic Letters. 2005, vol. 7, no. 25, p. 5637-5639
Abstract An expedient synthesis of (−)-pochonin A is reported (seven steps). This natural product is closely related to radicicol and was shown to be a 90 nM inhibitor of HSP90.
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MOULIN, Emilie, BARLUENGA, Sofia, WINSSINGER, Nicolas. Concise Synthesis of Pochonin A, an HSP90 Inhibitor. In: Organic Letters, 2005, vol. 7, n° 25, p. 5637-5639. doi: 10.1021/ol052263+

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Deposited on : 2012-12-12

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