en
Scientific article
English

Synthesis of a PNA-encoded cysteine protease inhibitor library

Published inTetrahedron, vol. 60, no. 39, p. 8677-8690
Publication date2004
Abstract

Peptide nucleic acids (PNAs) have been used to encode a combinatorial library whereby each compound is labeled with a PNA tag which reflects its synthetic history and localizes the compound upon hybridization to an oligonucleotide array. We report herein the full synthetic details for a 4000 member PNA-encoded library targeted towards cysteine protease.

Keywords
  • Microarrays
  • Combinatorial chemistry
  • Protease inhibitors
  • Peptide nucleic acid
Affiliation Not a UNIGE publication
Citation (ISO format)
DEBAENE, François et al. Synthesis of a PNA-encoded cysteine protease inhibitor library. In: Tetrahedron, 2004, vol. 60, n° 39, p. 8677–8690. doi: 10.1016/j.tet.2004.05.107
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0040-4020
565views
3downloads

Technical informations

Creation12/11/2012 4:46:00 PM
First validation12/11/2012 4:46:00 PM
Update time03/14/2023 5:47:58 PM
Status update03/14/2023 5:47:57 PM
Last indexation01/16/2024 12:40:49 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack