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Ruthenium-based Photocatalysis in Templated Reactions

Published in Chimia. 2018, vol. 72, no. 4, p. 207-211
Abstract Templated reactions proceed by bringing reagents in close proximity through their interaction with a template thus raising their effective concentrations. Templated reactions empower chemists to perform reactions at low concentrations in complex environments. Herein, we discuss our work on templated reactions leveraged on ruthenium photocatalysis. Over the past five years, we have used this reaction to uncage reporter molecules and sense or image nucleic acids or proteins of interest. The ruthenium photocatalysis chemistry has proven to be extremely robust and compatible with complex biological environments.
Keywords Fluorescent probesNucleic acid sensingProtein imagingRuthenium photocatalysisTemplated chemistry
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Research group Groupe Winssinger
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SAARBACH, Jacques, LINDBERG, Eric, WINSSINGER, Nicolas. Ruthenium-based Photocatalysis in Templated Reactions. In: Chimia, 2018, vol. 72, n° 4, p. 207-211. doi: 10.2533/chimia.2018.207 https://archive-ouverte.unige.ch/unige:105650

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Deposited on : 2018-06-18

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