In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis

Sadhu, Kalyan Kumar; Lindberg, Eric; Winssinger, Nicolas

doi:10.1039/C5CC05405B

Scientific article

English

In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis

ContributorsSadhu, Kalyan Kumar; Lindberg, Eric; Winssinger, Nicolas

Published inChemical communications, vol. 51, no. 93, p. 16664-16666

Publication date2015

Abstract

Labelling of proteins with a luminescent ruthenium complex enables the direct visualization and photocatalytic reduction of aryl azide in live cells. The confinement of catalysis to the labeled proteins was visualized using an azide-based immolative linker releasing a precipitating dye.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Research groups

Groupe Winssinger

Citation (ISO format)

SADHU, Kalyan Kumar, LINDBERG, Eric, WINSSINGER, Nicolas. In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis. In: Chemical communications, 2015, vol. 51, n° 93, p. 16664–16666. doi: 10.1039/C5CC05405B

Article (Published version)

Identifiers

PID : unige:77316
DOI : 10.1039/C5CC05405B

Additional URL for this publicationhttp://xlink.rsc.org/?DOI=C5CC05405B

Journal ISSN1359-7345

682views

8downloads

Creation11/11/2015 16:43:00

First validation11/11/2015 16:43:00

Update time14/03/2023 23:49:48

Status update14/03/2023 23:49:48

Last indexation31/10/2024 01:54:52

Archive ouverte UNIGE

In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis

Labelling of proteins with a luminescent ruthenium complex enables the direct visualization and photocatalytic reduction of aryl azide in live cells. The confinement of catalysis to the labeled proteins was visualized using an azide-based immolative linker releasing a precipitating dye.

Technical informations