Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics

Nicolaou, K. C.; Boddy, Christopher N. C.; Bräse, Stefan; Winssinger, Nicolas

doi:10.1002/(SICI)1521-3773(19990802)38:15<2096::AID-ANIE2096>3.0.CO;2-F

Scientific article

English

Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics

ContributorsNicolaou, K. C.; Boddy, Christopher N. C.; Bräse, Stefan; Winssinger, Nicolas

Published inAngewandte Chemie, vol. 38, no. 15, p. 2096-2152

Publication date1999

Abstract

The war against infectious bacteria is not over! Although vancomycin and glycopeptide antibiotics have provided a strong last line of defence against many drug-resistant bacteria, their overuse has given rise to more dangerous strains of bacteria. An understanding of the chemistry and biology of these highly complex glycopeptides are destined to play a crucial role in the discovery of new antibiotics.

Keywords

Biaryls
Glycopeptides
Mode of action
Total synthesis
Vancomycin

Affiliation Not a UNIGE publication

Citation (ISO format)

NICOLAOU, K. C. et al. Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics. In: Angewandte Chemie, 1999, vol. 38, n° 15, p. 2096–2152. doi: 10.1002/(SICI)1521-3773(19990802)38:15<2096::AID-ANIE2096>3.0.CO;2-F

Article (Published version)

Identifiers

PID : unige:24511
DOI : 10.1002/(SICI)1521-3773(19990802)38:15<2096::AID-ANIE2096>3.0.CO;2-F

ISSN of the journal1433-7851

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Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics

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