UNIGE document Scientific Article
previous document  unige:73083  next document
add to browser collection
Title

DNA display of glycoconjugates to emulate oligomeric interactions of glycans

Authors
Published in Beilstein Journal of Organic Chemistry. 2015, vol. 11, p. 707-719
Abstract Glycans (carbohydrate portion of glycoproteins and glycolipids) frequently exert their function through oligomeric interactions involving multiple carbohydrate units. In efforts to recapitulate the diverse spatial arrangements of the carbohydrate units, assemblies based on hybridization of nucleic acid conjugates have been used to display simplified ligands with tailored interligand distances and valences. The programmability of the assemblies lends itself to a combinatorial display of multiple ligands. Recent efforts in the synthesis and applications of such conjugates are discussed.
Keywords GlycanGlycoconjugateDNA displayMultivalencyNucleic acid conjugatesOligomeric interaction
Identifiers
Full text
Structures
Citation
(ISO format)
NOVOA, Alexandre, WINSSINGER, Nicolas. DNA display of glycoconjugates to emulate oligomeric interactions of glycans. In: Beilstein Journal of Organic Chemistry, 2015, vol. 11, p. 707-719. https://archive-ouverte.unige.ch/unige:73083

236 hits

103 downloads

Update

Deposited on : 2015-06-09

Export document
Format :
Citation style :