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Limited access to UNIGEOther version: http://linkinghub.elsevier.com/retrieve/pii/S1367593115000162
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unige:46712 
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PNA-encoded chemical libraries |
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| Published in | Current Opinion in Chemical Biology. 2015, vol. 26, p. 8-15 | |
| Abstract | Peptide nucleic acid (PNA)-encoded chemical libraries along with DNA-encoded libraries have provided a powerful new paradigm for library synthesis and ligand discovery. PNA-encoding stands out for its compatibility with standard solid phase synthesis and the technology has been used to prepare libraries of peptides, heterocycles and glycoconjugates. Different screening formats have now been reported including selection-based and microarray-based methods that have yielded specific ligands against diverse target classes including membrane receptors, lectins and challenging targets such as Hsp70. | |
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Article (Published version) (820 Kb) - Limited access to UNIGE Other version: http://linkinghub.elsevier.com/retrieve/pii/S1367593115000162 |
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| Structures | ||
| Citation (ISO format) | ZAMBALDO, Claudio, BARLUENGA BADIOLA, Sofia, WINSSINGER, Nicolas. PNA-encoded chemical libraries. In: Current Opinion in Chemical Biology, 2015, vol. 26, p. 8-15. https://archive-ouverte.unige.ch/unige:46712 |
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