DB
Bosco, Domenico
Affiliation entities
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Lysophosphatidylinositols Are Upregulated After Human β-Cell Loss and Potentiate Insulin Release | Diabetes | 2024 | 272 | 1 | |||
Intercellular contacts affect secretion and biosynthesis of pancreatic islet cells | Journal of endocrinology | 2023 | 44 | 44 | |||
Islets-on-chip : a tool for real-time assessment of islet function prior to transplantation | Transplant international | 2023 | 45 | 16 | |||
Bio-Engineering of Pre-Vascularized Islet Organoids for the Treatment of Type 1 Diabetes | Transplant international | 2022 | 404 | 166 | |||
Feasibility and efficacy of combined pancreatic islet-lung transplantation in cystic fibrosis related diabetes - PIM study: a multicenter phase 1-2 trial | American journal of transplantation | 2022 | 333 | 87 | |||
402.7: Homemade hydrogel from human amniotic membrane improves islet transplantation outcomes in diabetic immunodeficient mice | Transplantation | 2021 | 181 | 2 | |||
P.169: Decellularized cotyledons isolated from human placenta used like a scaffold for the generation of a human bioartificial pancreas | Transplantation | 2021 | 146 | 1 | |||
Failure mode and effect analysis in human islet isolation: from the theoretical to the practical risk | Islets | 2021 | 164 | 0 | |||
Dynamic uni- and multicellular patterns encode biphasic activity in pancreatic islets | Diabetes | 2021 | 178 | 89 | |||
Impact of ischemia time on islet isolation success and posttransplantation outcomes: A retrospective study of 452 pancreas isolations | American journal of transplantation | 2021 | 201 | 0 | |||
Biosynthetic activity differs between islet cell types and in beta cells is modulated by glucose and not by secretion | Endocrinology | 2021 | 249 | 91 | |||
402.5: Human Amniotic Epithelial Cells Immunomodulatory Properties Protect Islets Against Inflammatory Cytokines In Vitro | Transplantation | 2021 | 168 | 1 | |||
Pancréatectomie totale et autotransplantation d'îlots : état actuel et nouvelles perspectives, | Revue médicale suisse | 2021 | 322 | 3 | |||
Ten-years outcomes of islet transplantation in patients with type 1 diabetes: data from the Swiss-French GRAGIL network | American Journal of Transplantation | 2021 | 159 | 131 | |||
Pancreas collagen digestion during islet of Langerhans isolation | Transplant International | 2020 | 220 | 207 | |||
Loss of cell-cell and cell-substrate contacts in single pancreatic β-cells divert insulin release to intracellular vesicular compartments | Biology of the Cell | 2020 | 264 | 41 | |||
Generation of insulin-secreting organoids: a step toward engineering and transplanting the bioartificial pancreas | Transplant International | 2020 | 273 | 135 | |||
Beta-cell-specific expression of NOX5 aggravates high fat diet-induced impairment of islet insulin secretion in mice | Antioxidants & Redox Signaling | 2020 | 401 | 222 | |||
Interest of plasma microvesicles to monitor pancreatic islet graft dysfunction: beta cell- and leukocyte-derived microvesicles as specific features in a pilot longitudinal study | American Journal of Transplantation | 2020 | 279 | 350 | |||
Engineering of primary pancreatic islet cell spheroids for three-dimensional culture or transplantation: a methodological comparative study | Cell Transplantation | 2020 | 343 | 172 | |||
NLRP3 inflammasome is activated in rat pancreatic islets by transplantation and hypoxia | Scientific Reports | 2020 | 266 | 139 | |||
Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study | Transplantation | 2020 | 265 | 102 | |||
Syndecan-4 is regulated by IL-1β in β-cells and human islets | Molecular and Cellular Endocrinology | 2020 | 231 | 102 | |||
Shielding islets with human amniotic epithelial cells enhances islet engraftment and revascularization in a murine diabetes model | American Journal of Transplantation | 2020 | 267 | 168 | |||
Chronic fructose renders pancreatic beta-cells hyper-responsive to glucose-stimulated insulin secretion through extracellular ATP signaling | American Journal of Physiology. Endocrinology and Metabolism | 2019 | 515 | 731 | |||
Transient PAX8 Expression in Islets During Pregnancy Correlates With β-Cell Survival, Revealing a Novel Candidate Gene in Gestational Diabetes Mellitus | Diabetes | 2019 | 315 | 266 | |||
Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes | Nature Communications | 2019 | 360 | 236 | |||
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells | Nature | 2019 | 674 | 12 | |||
Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes | Scientific Reports | 2019 | 376 | 186 | |||
Islets for research: nothing is perfect, but we can do better | Diabetes | 2019 | 257 | 0 | |||
Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice | Scientific Reports | 2019 | 286 | 102 | |||
Successful pregnancy and delivery after simultaneous islet-kidney transplantation | American Journal of Transplantation | 2018 | 483 | 198 | |||
Pancreas preservation fluid microbial contamination is associated with poor islet isolation outcomes - a multi centre cohort study | Transplant International | 2018 | 477 | 316 | |||
Targeting GLP-1 receptor trafficking to improve agonist efficacy | Nature Communications | 2018 | 294 | 389 | |||
LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus | Nature Communications | 2018 | 368 | 175 | |||
NLRP3 inflammasome is expressed and regulated in human islets | Cell Death & Disease | 2018 | 463 | 191 | |||
Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial | The Lancet Diabetes & Endocrinology | 2018 | 465 | 0 | |||
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells | Diabetes | 2018 | 371 | 253 | |||
Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression | Genes and Development | 2017 | 548 | 13 | |||
Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores | Diabetes | 2016 | 420 | 0 | |||
Cell rearrangement in transplanted human islets | The FASEB journal | 2016 | 595 | 0 | |||
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose | Cell Metabolism | 2016 | 468 | 187 | |||
Activation of nicotinic acetylcholine receptors decreases apoptosis in human and female murine pancreatic islets | Endocrinology | 2016 | 524 | 243 | |||
Asymmetrical distribution of δ and PP cells in human pancreatic islets | Journal of Endocrinology | 2016 | 505 | 0 | |||
Human islet distribution programme for basic research: activity over the last 5 years | Diabetologia | 2015 | 569 | 0 | |||
Cadherin Engagement Improves Insulin Secretion of Single Human β-Cells | Diabetes | 2015 | 769 | 1 | |||
Five-Year Metabolic, Functional, and Safety Results of Patients With Type 1 Diabetes Transplanted With Allogenic Islets Within the Swiss-French GRAGIL Network | Diabetes care | 2015 | 525 | 0 | |||
The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes | Nature medicine | 2015 | 708 | 1,028 | |||
Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade | Transplantation | 2015 | 811 | 5 | |||
Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets | Human molecular genetics | 2015 | 659 | 294 | |||
Inflammatory Chemokines MIP-1δ and MIP-3α Are Involved in the Migration of Multipotent Mesenchymal Stromal Cells Induced by Hepatoma Cells | Stem cells and development | 2015 | 818 | 1 | |||
Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells | Diabetologia | 2015 | 585 | 2 | |||
ADCY5 Couples Glucose to Insulin Secretion in Human Islets | Diabetes | 2014 | 546 | 0 | |||
Incretin-modulated beta cell energetics in intact islets of Langerhans | Molecular endocrinology | 2014 | 656 | 715 | |||
Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn(2+) in pancreatic beta cells | Diabetologia | 2014 | 592 | 352 | |||
Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets | PloS one | 2014 | 612 | 246 | |||
Islet of Langerhans isolation from pediatric and juvenile donor pancreases | Transplant international | 2014 | 848 | 1 | |||
Impact of anti-insulin antibodies on islet transplantation outcome: data from the GRAGIL Network | Transplantation | 2014 | 548 | 0 | |||
Calcineurin inhibitor-free immunosuppressive regimen in type 1 diabetes patients receiving islet transplantation: single-group phase 1/2 trial | Transplantation | 2014 | 518 | 0 | |||
Survival of free and encapsulated human and rat islet xenografts transplanted into the mouse bone marrow | PloS one | 2014 | 808 | 276 | |||
Quantification of islet loss and graft functionality during immune rejection by 3-tesla MRI in a rat model | Transplantation | 2013 | 647 | 0 | |||
Cell-type, allelic and genetic signatures in the human pancreatic beta cell transcriptome | Genome research | 2013 | 647 | 451 | |||
Lipotoxicity disrupts incretin-regulated human β cell connectivity | The Journal of clinical investigation | 2013 | 457 | 0 | |||
Transplanted human pancreatic islets after long-term insulin independence | American journal of transplantation | 2013 | 759 | 1 | |||
Autonomous and self-sustained circadian oscillators displayed in human islet cells | Diabetologia | 2013 | 653 | 151 | |||
Losartan, an angiotensin II type 1 receptor blocker, protects human islets from glucotoxicity through the phospholipase C pathway | The FASEB journal | 2013 | 609 | 0 | |||
Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants | Diabetes care | 2013 | 769 | 0 | |||
Pancreatic magnetic resonance imaging after manganese injection distinguishes type 2 diabetic and normoglycemic patients | Islets | 2012 | 637 | 298 | |||
Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior | Transplantation | 2012 | 855 | 0 | |||
Islet autotransplantation after extended pancreatectomy for focal benign disease of the pancreas | Transplantation | 2011 | 753 | 0 | |||
Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism | The Journal of biological chemistry | 2011 | 608 | 1 | |||
Rapamycin impairs proliferation of transplanted islet β cells | Transplantation | 2011 | 691 | 1 | |||
Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass | Cell metabolism | 2011 | 585 | 0 | |||
Connexins: key mediators of endocrine function | Physiological reviews | 2011 | 575 | 887 | |||
A novel method for quantitative monitoring of transplanted islets of langerhans by positive contrast magnetic resonance imaging | American journal of transplantation | 2011 | 608 | 1 | |||
Impact of the number of infusions on 2-year results of islet-after-kidney transplantation in the GRAGIL network | Transplantation | 2011 | 588 | 2 | |||
Cadherin engagement protects human β-cells from apoptosis | Endocrinology | 2011 | 800 | 360 | |||
Influence of donor age on islet isolation and transplantation outcome | Transplantation | 2011 | 758 | 0 | |||
The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis | Human molecular genetics | 2011 | 694 | 0 | |||
Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo | Diabetes, obesity & metabolism | 2011 | 615 | 0 | |||
Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors | PloS one | 2010 | 796 | 294 | |||
Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism | Diabetologia | 2010 | 746 | 105 | |||
Macrophage migration inhibitory factor deficiency leads to age-dependent impairment of glucose homeostasis in mice | Journal of Endocrinology | 2010 | 709 | 0 | |||
Assessment of human islet labeling with clinical grade iron nanoparticles prior to transplantation for graft monitoring by MRI | Cell transplantation | 2010 | 781 | 1 | |||
A map of open chromatin in human pancreatic islets | Nature genetics | 2010 | 730 | 439 | |||
Combined pancreatic islet-lung transplantation: a novel approach to the treatment of end-stage cystic fibrosis | American journal of transplantation | 2010 | 722 | 0 | |||
Unique arrangement of alpha- and beta-cells in human islets of Langerhans | Diabetes | 2010 | 753 | 1 | |||
Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression | Human molecular genetics | 2009 | 709 | 150 | |||
Transplantation de pancréas et d'ilôts de Langerhans: le point en 2009 et le futur | Revue médicale suisse | 2009 | 609 | 0 | |||
Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function | Endocrinology | 2009 | 627 | 0 | |||
Immunomodulation by blockade of the TRANCE co-stimulatory pathway in murine allogeneic islet transplantation | Transplant international | 2009 | 739 | 0 | |||
Fibrogenic potential of human multipotent mesenchymal stromal cells in injured liver | PloS one | 2009 | 836 | 391 | |||
Regulated laminin-332 expression in human islets of Langerhans | The FASEB journal | 2009 | 823 | 0 | |||
Proliferation of sorted human and rat beta cells | Diabetologia | 2008 | 802 | 183 | |||
The role of macrophage migration inhibitory factor in mouse islet transplantation | Transplantation | 2008 | 784 | 0 | |||
Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts | Diabetologia | 2008 | 746 | 158 | |||
Mesenchymal stem cells derived from human exocrine pancreas express transcription factors implicated in beta-cell development | Pancreas | 2008 | 788 | 0 | |||
Combined pancreatic islet-lung transplantation with islet percutaneous portal embolization in cystic fibrosis | Transplantation | 2008 | 657 | 0 | |||
Computer-assisted digital image analysis to quantify the mass and purity of isolated human islets before transplantation | Transplantation | 2008 | 695 | 3 | |||
Clinical magnetic resonance imaging of pancreatic islet grafts after iron nanoparticle labeling | American journal of transplantation | 2008 | 680 | 0 | |||
Prévention du diabète après pancréatectomie pour maladie bénigne : le rôle de l'autotransplantation des îlots de Langerhans | Revue médicale suisse | 2007 | 635 | 0 | |||
The Fas pathway is involved in pancreatic beta cell secretory function | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 616 | 0 | |||
Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity | Journal of Endocrinology | 2007 | 534 | 0 | |||
Expectations and strategies regarding islet transplantation: metabolic data from the GRAGIL 2 trial | Transplantation | 2007 | 740 | 0 | |||
Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix | Diabetes | 2006 | 577 | 0 | |||
Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1 | Diabetes | 2006 | 656 | 601 | |||
Formation postgraduée des médecins camerounais à Genève | Revue médicale suisse | 2006 | 454 | 1 | |||
Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation | Cell transplantation | 2006 | 642 | 0 | |||
Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets | Diabetes | 2006 | 707 | 873 | |||
Sequential kidney/islet transplantation: efficacy and safety assessment of a steroid-free immunosuppression protocol | American journal of transplantation | 2006 | 798 | 238 | |||
Detection of insulin mRNA in the peripheral blood after human islet transplantion predicts deterioration of metabolic control | American journal of transplantation | 2006 | 802 | 263 | |||
Inhibition of calpain blocks pancreatic beta-cell spreading and insulin secretion | American journal of physiology: endocrinology and metabolism | 2005 | 577 | 247 | |||
Role of CD40-CD154 pathway in the rejection of concordant and discordant xenogeneic islets | Transplantation proceedings | 2005 | 828 | 0 | |||
Treatment of fulminant liver failure by transplantation of microencapsulated primary or immortalized xenogeneic hepatocytes | Transplantation proceedings | 2005 | 832 | 0 | |||
Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitro | Stem cells | 2005 | 728 | 864 | |||
Microbial surveillance during human pancreatic islet isolation | Transplant international | 2005 | 892 | 0 | |||
Sulfonylurea induced beta-cell apoptosis in cultured human islets | The Journal of clinical endocrinology and metabolism | 2005 | 537 | 212 | |||
Activation of NF-kappaB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells | The Journal of biological chemistry | 2005 | 477 | 168 | |||
Expression and secretion of alpha1-proteinase inhibitor are regulated by proinflammatory cytokines in human pancreatic islet cells | Diabetologia | 2005 | 728 | 162 | |||
Positron-emission tomography imaging of early events after transplantation of islets of Langerhans | Transplantation | 2005 | 731 | 0 | |||
Macrophage depletion prolongs discordant but not concordant islet xenograft survival | Transplantation | 2005 | 746 | 0 | |||
Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154 | Transplantation | 2005 | 718 | 0 | |||
Islet transplantation in a recipient presenting the factor V Leiden mutation | Transplantation | 2005 | 769 | 0 | |||
Treatment of fulminant liver failure by transplantation of microencapsulated primary or immortalized xenogeneic hepatocytes | Xenotransplantation | 2005 | 735 | 0 | |||
Effect of microcapsule composition and short-term immunosuppression on intraportal biocompatibility | Cell transplantation | 2005 | 760 | 0 | |||
Impairment of renal function after islet transplant alone or islet-after-kidney transplantation using a sirolimus/tacrolimus-based immunosuppressive regimen | Transplant international | 2005 | 774 | 0 | |||
Anti-CD154 mAb treatment but not recipient CD154 deficiency leads to long-term survival of xenogeneic islet grafts | American journal of transplantation | 2005 | 753 | 298 | |||
A comparison of cold storage solutions for pancreas preservation prior to islet isolation | Transplantation proceedings | 2005 | 732 | 0 | |||
Logistics and transplant coordination activity in the GRAGIL Swiss-French multicenter network of islet transplantation | Transplantation | 2005 | 710 | 0 | |||
Impact of a sirolimus/tacrolimus-based immunosuppressive regimen on kidney function after islet transplantation | Transplantation proceedings | 2005 | 734 | 0 | |||
Phylogenetic disparity influences the predominance of direct over indirect pathway of antigen presentation in islet xenotransplantation | Transplantation proceedings | 2005 | 746 | 1 | |||
Role of chemokine signaling pathways in pancreatic islet rejection during allo- and xenotransplantation | Transplantation proceedings | 2005 | 502 | 0 | |||
Le traitement du diabète de type I par transplantation | Annales de chirurgie | 2005 | 668 | 0 | |||
Assessment of a novel two-component enzyme preparation for human islet isolation and transplantation | Transplantation | 2005 | 747 | 0 | |||
Short-term immunosuppression reduces fibrotic cellular infiltration around barium-M-alginate microbeads injected intraportally | Transplantation proceedings | 2004 | 704 | 0 | |||
Islet autotransplantation for the prevention of surgical diabetes after extended pancreatectomy for the resection of benign tumors of the pancreas | Transplantation proceedings | 2004 | 739 | 0 | |||
Microbial surveillance during human pancreatic islet isolation | Transplantation proceedings | 2004 | 736 | 0 | |||
Extracellular matrix protects pancreatic beta-cells against apoptosis: role of short- and long-term signaling pathways | Diabetes | 2004 | 590 | 606 | |||
Retransplantation of discordant xenogeneic islets with costimulatory blockade | Transplantation proceedings | 2004 | 713 | 0 | |||
Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 550 | 0 | |||
Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations | Transplantation proceedings | 2004 | 727 | 1 | |||
Serva collagenase NB1: a new enzyme preparation for human islet isolation | Transplantation proceedings | 2004 | 610 | 0 | |||
Morbidity associated with intraportal islet transplantation | Transplantation proceedings | 2004 | 752 | 0 | |||
Pioglitazone and sodium salicylate protect human beta-cells against apoptosis and impaired function induced by glucose and interleukin-1beta | The Journal of clinical endocrinology and metabolism | 2004 | 567 | 0 | |||
Optimization of neutral protease to collagenase activity ratio for islet of Langerhans isolation | Transplantation proceedings | 2004 | 717 | 0 | |||
Autotransplantation d'îlots de Langerhans pour la prévention du diabète après résection pancréatique étendue | Médecine et hygiène | 2003 | 623 | 0 | |||
Kidney-pancreas transplantation in a long-term non-progressor HIV-infected recipient | American journal of transplantation | 2003 | 738 | 344 | |||
Islet of Langerhans transplantation for the treatment of type 1 diabetes | Swiss surgery | 2003 | 677 | 0 | |||
Islet autotransplantation after left pancreatectomy for non-enucleable insulinoma | American journal of transplantation | 2003 | 761 | 574 | |||
Intra-portal injection of 400- microm microcapsules in a large-animal model | Transplant international | 2003 | 691 | 1 | |||
Insulin independence after conversion to tacrolimus and sirolimus-based immunosuppression in islet-kidney recipients | Transplantation | 2003 | 681 | 1 | |||
Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro | Diabetologia | 2002 | 779 | 0 | |||
Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix | Diabetes | 2001 | 561 | 0 | |||
Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin | Diabetes | 2000 | 516 | 0 | |||
Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance | The Journal of clinical investigation | 2000 | 510 | 0 | |||
Enhanced secretion of amylase from exocrine pancreas of connexin32-deficient mice | The Journal of cell biology | 1998 | 546 | 0 | |||
Sorting human beta-cells consequent to targeted expression of green fluorescent protein | Diabetes | 1998 | 723 | 0 | |||
Protease-nexin I as an androgen-dependent secretory product of the murine seminal vesicle | EMBO journal | 1993 | 597 | 0 | |||
B-cell size influences glucose-stimulated insulin secretion | The American journal of physiology | 1993 | 553 | 0 | |||
Plasminogen activator and mouse spermatozoa: urokinase synthesis in the male genital tract and binding of the enzyme to the sperm cell surface | The Journal of cell biology | 1987 | 571 | 0 |