Treatment of fulminant liver failure by transplantation of microencapsulated primary or immortalized xenogeneic hepatocytes

Mai, Gang; Nguyen, Tuan Huy; Morel, Philippe; Mei, Jie; Andres, Axel; Bosco, Domenico; Baertschiger, Reto Marc; Toso, Christian; Berney, Thierry; Majno, Pietro; Mentha, Gilles; Trono, Didier; Buehler, Leo Hans

doi:10.1111/j.1399-3089.2005.00248.x

Scientific article

English

Treatment of fulminant liver failure by transplantation of microencapsulated primary or immortalized xenogeneic hepatocytes

ContributorsMai, Gang; Nguyen, Tuan Huy; Morel, Philippe; Mei, Jie; Andres, Axel; Bosco, Domenico; Baertschiger, Reto Marc; Toso, Christian

; Berney, Thierry; Majno, Pietro; Mentha, Gilles; Trono, Didier; Buehler, Leo Hans

Published inXenotransplantation, vol. 12, no. 6, p. 457-464

Publication date2005

Abstract

The aim of this study was to evaluate in vitro and in vivo functions of isolated hepatocytes after immortalization, cryopreservation, encapsulation and xenotransplantation into mice with fulminant liver failure (FLF).

Keywords

Albumins/secretion
Animals
Cell Proliferation
Cells, Cultured
Hepatocytes/cytology/secretion/transplantation
Humans
Liver Failure, Acute/surgery
Male
Mice
Rats
Survival Rate
Transplantation, Heterologous

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Citation (ISO format)

MAI, Gang et al. Treatment of fulminant liver failure by transplantation of microencapsulated primary or immortalized xenogeneic hepatocytes. In: Xenotransplantation, 2005, vol. 12, n° 6, p. 457–464. doi: 10.1111/j.1399-3089.2005.00248.x

Article (Published version)

Identifiers

PID : unige:37075
DOI : 10.1111/j.1399-3089.2005.00248.x
PMID : 16202069

Journal ISSN0908-665X

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Treatment of fulminant liver failure by transplantation of microencapsulated primary or immortalized xenogeneic hepatocytes

The aim of this study was to evaluate in vitro and in vivo functions of isolated hepatocytes after immortalization, cryopreservation, encapsulation and xenotransplantation into mice with fulminant liver failure (FLF).

Technical informations