Role of CD40-CD154 pathway in the rejection of concordant and discordant xenogeneic islets

Mai, Gang; Bucher, Pascal Alain Robert; Morel, Philippe; Mei, Jie; Bosco, Domenico; Andres, Axel; Mathe, Z; Wekerle, T; Berney, Thierry; Buehler, Leo Hans

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Title		Role of CD40-CD154 pathway in the rejection of concordant and discordant xenogeneic islets
Authors		Mai, Gang Bucher, Pascal Alain Robert Morel, Philippe Mei, Jie Bosco, Domenico Andres, Axel Mathe, Z Wekerle, T Berney, Thierry Buehler, Leo Hans show all authors [1 - 10]
Published in		Transplantation Proceedings. 2005, vol. 37, no. 1, p. 460-2
Abstract		Costimulatory blockade has been shown to allow long-term survival of xenogeneic islets. The aim of the present study was to evaluate the role of recipient CD40 and CD154 in the rejection process of concordant and discordant islet xenotransplantation (Tx).
Keywords		Animals — Antigens, CD40/genetics/physiology — CD40 Ligand/genetics/physiology — Gene Deletion — Graft Rejection/pathology — Humans — Islets of Langerhans Transplantation/pathology — Lymphocyte Culture Test, Mixed — Mice — Mice, Inbred C57BL — Mice, Knockout — Rats — Transplantation, Heterologous/pathology
Identifiers		DOI: 10.1016/j.transproceed.2004.12.306 PMID: 15808676
Full text		Article (Published version) (51 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de chirurgie
Research groups		Chirurgie viscérale (104) La transplantation d'îlots de Langerhans (623) Cultures cellulaires et transplantations (519)
Citation (ISO format)		MAI, Gang et al. Role of CD40-CD154 pathway in the rejection of concordant and discordant xenogeneic islets. In: Transplantation Proceedings, 2005, vol. 37, n° 1, p. 460-2. https://archive-ouverte.unige.ch/unige:39999