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Transplantation de pancréas et d'ilôts de Langerhans: le point en 2009 et le futur

Published in Revue médicale suisse. 2009, vol. 5, no. 206, p. 1266-70,1272
Abstract Type 1 diabetes currently affects 15,000 patients in Switzerland with a rising incidence worldwide. Pancreas or islet of Langerhans transplantation are alternatives to intensive insulin treatment, which decreases long-term complications at the cost of an increase of severe hyoglycemia. Pancreas transplantation, indicated mainly to diabetic patients with simultaneous kidney transplantation, has a high success rate, but is accompanied by high morbidity due to general surgery. Islet transplantation, a cell-therapy for type 1 diabetes, is in full development. It is mainly indicated as islet transplant alone in patients suffering from brittle diabetes, and is associated with a very low risk due to minimally invasive technique, but a lower rate of long-term success. New potential sources of beta cell replacement are beta-cell lines, stem cells and xenotransplantation.
Keywords Diabetes Mellitus, Type 1/surgeryHumansIslets of Langerhans TransplantationPancreas Transplantation
PMID: 19579422
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Other version: http://rms.medhyg.ch/numero-206-page-1266.htm
Research groups Chirurgie viscérale (104)
Chirurgie viscérale (HUG)
La transplantation d'îlots de Langerhans (623)
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NICLAUSS, Nadja et al. Transplantation de pancréas et d'ilôts de Langerhans: le point en 2009 et le futur. In: Revue médicale suisse, 2009, vol. 5, n° 206, p. 1266-70,1272. https://archive-ouverte.unige.ch/unige:32416

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Deposited on : 2013-12-18

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