Impact of anti-insulin antibodies on islet transplantation outcome: data from the GRAGIL Network

Lablanche, Sandrine; Borot, Sophie; Thaunat, Olivier; Bayle, Francois; Badet, Lionel; Morelon, Emmanuel; Thivolet, Charles; Wojtusciszyn, Anne; Frimat, Luc; Kessler, Laurence; Penfornis, Alfred; Brault, Coralie; Colin, Cyrille; Bosco, Domenico; Berney, Thierry; Benhamou, Pierre Y

doi:10.1097/TP.0000000000000081

Scientific article

English

Impact of anti-insulin antibodies on islet transplantation outcome: data from the GRAGIL Network

ContributorsLablanche, Sandrine; Borot, Sophie; Thaunat, Olivier; Bayle, Francois; Badet, Lionel; Morelon, Emmanuel; Thivolet, Charles; Wojtusciszyn, Anne; Frimat, Luc; Kessler, Laurence; Penfornis, Alfred; Brault, Coralie; Colin, Cyrille; Bosco, Domenico; Berney, Thierry; Benhamou, Pierre Y

Published inTransplantation, vol. 98, no. 4, p. 475-482

Publication date2014

Abstract

In patients with type 1 diabetes, insulin antibodies (IA), altering the pharmacokinetics of circulating insulin, might be associated with high glucose concentration, prolonged hypoglycemia, and higher insulin requirement. The impact of IA on islet transplantation has never been explored. Our aim was to evaluate islet transplantation results at 1 year according to the presence of IA.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Citation (ISO format)

LABLANCHE, Sandrine et al. Impact of anti-insulin antibodies on islet transplantation outcome: data from the GRAGIL Network. In: Transplantation, 2014, vol. 98, n° 4, p. 475–482. doi: 10.1097/TP.0000000000000081

Article (Accepted version)

Identifiers

PID : unige:40985
DOI : 10.1097/TP.0000000000000081
PMID : 24837539

ISSN of the journal0041-1337

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Impact of anti-insulin antibodies on islet transplantation outcome: data from the GRAGIL Network

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