Autonomous and self-sustained circadian oscillators displayed in human islet cells

Pulimeno, Pamela; Mannic, Tiphaine; Sage, D; Giovannoni, Laurianne; Salmon, Patrick; Lemeille, Sylvain; Giry-Laterriere, Marc; Unser, M; Bosco, Domenico; Bauer, C; Morf, Jörg; Halban, Philippe A.; Philippe, Jacques; Dibner, Charna

doi:10.1007/s00125-012-2779-7

Scientific article

English

Autonomous and self-sustained circadian oscillators displayed in human islet cells

ContributorsPulimeno, Pamela; Mannic, Tiphaine; Sage, D; Giovannoni, Laurianne; Salmon, Patrick; Lemeille, Sylvain; Giry-Laterriere, Marc; Unser, M; Bosco, Domenico; Bauer, C; Morf, Jörg; Halban, Philippe A.; Philippe, Jacques; Dibner, Charna

Published inDiabetologia, vol. 56, no. 3, p. 497-507

Publication date2013

Abstract

Following on from the emerging importance of the pancreas circadian clock on islet function and the development of type 2 diabetes in rodent models, we aimed to examine circadian gene expression in human islets. The oscillator properties were assessed in intact islets as well as in beta cells.

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Citation (ISO format)

PULIMENO, Pamela et al. Autonomous and self-sustained circadian oscillators displayed in human islet cells. In: Diabetologia, 2013, vol. 56, n° 3, p. 497–507. doi: 10.1007/s00125-012-2779-7

Article (Published version)

OA NATIONAL

Identifiers

PID : unige:28878
DOI : 10.1007/s00125-012-2779-7
PMID : 23242133

Journal ISSN0012-186X

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Creation18/06/2013 11:18:00

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Autonomous and self-sustained circadian oscillators displayed in human islet cells

Following on from the emerging importance of the pancreas circadian clock on islet function and the development of type 2 diabetes in rodent models, we aimed to examine circadian gene expression in human islets. The oscillator properties were assessed in intact islets as well as in beta cells.

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