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Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154

Mathe, Zoltan
Wekerle, Thomas
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Published in Transplantation. 2005, vol. 79, no. 11, p. 1545-52
Abstract Costimulatory blockade has been shown to allow long-term survival of xenogeneic islets. The aim of the present study was to analyze the possibility of xenogeneic islet retransplantation using costimulatory blockade.
Keywords AnimalsAntibodies, Monoclonal/therapeutic useB-Lymphocytes/immunologyCD40 Ligand/immunologyCricetinaeDiabetes Mellitus, Experimental/surgeryGlucagon/analysisGraft Survival/immunologyHistocompatibility TestingHumansInsulin/analysisIslets of Langerhans Transplantation/immunology/physiologyMaleMiceMice, Inbred C57BLT-Lymphocytes/immunologyTissue DonorsTransplantation, Heterologous/immunology/physiology
PMID: 15940044
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Research groups Chirurgie viscérale (104)
Chirurgie viscérale (HUG)
Cultures cellulaires et transplantations (519)
La transplantation d'îlots de Langerhans (623)
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BUCHER, Pascal Alain Robert et al. Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154. In: Transplantation, 2005, vol. 79, n° 11, p. 1545-52. doi: 10.1097/01.tp.0000163505.63159.69 https://archive-ouverte.unige.ch/unige:39640

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Deposited on : 2014-08-22

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