Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154

Bucher, Pascal Alain Robert; Mai, Gang; Morel, Philippe; Mathe, Zoltan; Bosco, Domenico; Pernin, Nadine; Wekerle, Thomas; Berney, Thierry; Buehler, Leo Hans

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Title		Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154
Authors		Bucher, Pascal Alain Robert Mai, Gang Morel, Philippe Mathe, Zoltan Bosco, Domenico Pernin, Nadine Wekerle, Thomas Berney, Thierry Buehler, Leo Hans show all authors [1 - 9]
Published in		Transplantation. 2005, vol. 79, no. 11, p. 1545-52
Abstract		Costimulatory blockade has been shown to allow long-term survival of xenogeneic islets. The aim of the present study was to analyze the possibility of xenogeneic islet retransplantation using costimulatory blockade.
Keywords		Animals — Antibodies, Monoclonal/therapeutic use — B-Lymphocytes/immunology — CD40 Ligand/immunology — Cricetinae — Diabetes Mellitus, Experimental/surgery — Glucagon/analysis — Graft Survival/immunology — Histocompatibility Testing — Humans — Insulin/analysis — Islets of Langerhans Transplantation/immunology/physiology — Male — Mice — Mice, Inbred C57BL — T-Lymphocytes/immunology — Tissue Donors — Transplantation, Heterologous/immunology/physiology
Identifiers		DOI: 10.1097/01.tp.0000163505.63159.69 PMID: 15940044
Full text		Article (Published version) (1.4 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de chirurgie
Research groups		Chirurgie viscérale (104) La transplantation d'îlots de Langerhans (623) Cultures cellulaires et transplantations (519)
Citation (ISO format)		BUCHER, Pascal Alain Robert et al. Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154. In: Transplantation, 2005, vol. 79, n° 11, p. 1545-52. https://archive-ouverte.unige.ch/unige:39640