Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants

Elkhafif, Nabeel; Borot, Sophie; Morel, Philippe; Demuylder-Mischler, Sandrine; Giovannoni, Laurianne; Toso, Christian; Bosco, Domenico; Berney, Thierry

doi:10.2337/dc12-2710

Scientific article

English

Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants

ContributorsElkhafif, Nabeel; Borot, Sophie; Morel, Philippe; Demuylder-Mischler, Sandrine; Giovannoni, Laurianne; Toso, Christian; Bosco, Domenico; Berney, Thierry

Published inDiabetes care, vol. 36, no. 11, p. 3726-3731

Publication date2013

Abstract

β-Cells have demonstrated altered proinsulin processing after islet transplantation. We compare β-cell metabolic responses and proinsulin processing in pancreas and islet transplant recipients with respect to healthy control subjects.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Citation (ISO format)

ELKHAFIF, Nabeel et al. Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants. In: Diabetes care, 2013, vol. 36, n° 11, p. 3726–3731. doi: 10.2337/dc12-2710

Article (Published version)

Identifiers

PID : unige:34307
DOI : 10.2337/dc12-2710
PMID : 24041681

Journal ISSN0149-5992

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Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants

β-Cells have demonstrated altered proinsulin processing after islet transplantation. We compare β-cell metabolic responses and proinsulin processing in pancreas and islet transplant recipients with respect to healthy control subjects.

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