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Scientific article
French

Prévention du diabète après pancréatectomie pour maladie bénigne : le rôle de l'autotransplantation des îlots de Langerhans

Published inRevue médicale suisse, vol. 3, no. 117, p. 1627-1628,1630-1
Publication date2007
Abstract

Patients with benign pancreatic disease (chronic pancreatitis, benign tumors) requiring extensive pancreatic surgery are subject to major metabolic changes. Many of them are at risk of developing diabetes. Surgical diabetes is very difficult to manage because of the lack of counter regulation mechanisms. Islet autotransplantation after isolation from the resected pancreas allows to avoid the development of surgical diabetes. Insulin independance can be maintained in 40 to 50% of the patients. Success rate depends on the number of isolated and transplanted islets and on the type of pancreatic disease. Procedures-related complications are rare, the most frequent being thrombosis of the portal vein, through which the islets are transplanted. Islet autotransplantation has been used successfully in chronic pancreatitis and benign tumors.

Keywords
  • Diabetes Mellitus, Type 1/etiology/prevention & control
  • Humans
  • Islets of Langerhans Transplantation/methods
  • Pancreatectomy/adverse effects
  • Pancreatic Diseases/surgery
  • Pancreatic Neoplasms/surgery
  • Pancreatitis/surgery
  • Postoperative Complications/prevention & control
  • Transplantation, Autologous
Citation (ISO format)
RIS, Frédéric et al. Prévention du diabète après pancréatectomie pour maladie bénigne : le rôle de l’autotransplantation des îlots de Langerhans. In: Revue médicale suisse, 2007, vol. 3, n° 117, p. 1627–1628,1630–1.
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Article (Published version)
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Identifiers
ISSN of the journal1660-9379
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