Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism
Published inDiabetologia, vol. 53, no. 2, p. 331-340
Collection
- Open Access - Licence nationale Springer
Publication date2010
Abstract
Keywords
- Adenosine Triphosphate/metabolism
- Antigens, CD36/genetics
- Apoptosis/drug effects
- Carbohydrates/ physiology
- Carnitine O-Palmitoyltransferase/genetics
- Cell Culture Techniques
- Fatty Acids, Nonesterified/pharmacology
- Gene Expression Regulation
- Glucose/pharmacology
- Humans
- Insulin/secretion
- Insulin-Secreting Cells/cytology/drug effects/pathology/ physiology
- Oleic Acid/ toxicity
- PPAR alpha/pharmacology/ physiology
- Reverse Transcriptase Polymerase Chain Reaction
- Tubulin/genetics
Citation (ISO format)
FRIGERIO, Francesca et al. Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism. In: Diabetologia, 2010, vol. 53, n° 2, p. 331–340. doi: 10.1007/s00125-009-1590-6
Main files (1)
Article (Published version)
Identifiers
- PID : unige:20682
- DOI : 10.1007/s00125-009-1590-6
- PMID : 19908022
Commercial URLhttp://www.springerlink.com/content/100410/
ISSN of the journal0012-186X