Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior

Niclauss, Nadja; Wojtusciszyn, Anne; Morel, Philippe; Demuylder-Mischler, Sandrine; Brault, Coralie; Parnaud, Géraldine; Ris, Frédéric; Bosco, Domenico; Badet, Lionel; Benhamou, Pierre-Yves; Berney, Thierry

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Title		Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior
Authors		Niclauss, Nadja Wojtusciszyn, Anne Morel, Philippe Demuylder-Mischler, Sandrine Brault, Coralie Parnaud, Géraldine Ris, Frédéric Bosco, Domenico Badet, Lionel Benhamou, Pierre-Yves Berney, Thierry show all authors [1 - 11]
Published in		Transplantation. 2012, vol. 93, no. 7, p. 703-8
Abstract		Institut Georges Lopez-1 (IGL-1) is a preservation solution similar to University of Wisconsin (UW) with reversed Na/K contents. In this study, we assessed the impact of IGL-1, UW, and Celsior (CS) solutions on islet isolation and transplant outcome.
Keywords		Adenosine/therapeutic use — Adult — Allopurinol/therapeutic use — Analysis of Variance — Biological Markers/blood — Blood Glucose/metabolism — C-Peptide/blood — Chi-Square Distribution — Diabetes Mellitus/blood/drug therapy/surgery — Disaccharides/therapeutic use — Electrolytes/therapeutic use — Female — Glutamates/therapeutic use — Glutathione/therapeutic use — Hemoglobin A, Glycosylated/metabolism — Histidine/therapeutic use — Humans — Hypoglycemic Agents/therapeutic use — Insulin/therapeutic use — Islets of Langerhans/drug effects/metabolism — Islets of Langerhans Transplantation — Male — Mannitol/therapeutic use — Middle Aged — Organ Preservation/methods — Organ Preservation Solutions/therapeutic use — Raffinose/therapeutic use — Retrospective Studies — Time Factors — Tissue Culture Techniques — Tissue and Organ Harvesting/methods — Treatment Outcome
Identifiers		DOI: 10.1097/TP.0b013e3182476cc8 PMID: 22343333
Full text		Article (Published version) (254 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de chirurgie
Research groups		La transplantation d'îlots de Langerhans (623) Chirurgie viscérale (104)
Citation (ISO format)		NICLAUSS, Nadja et al. Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior. In: Transplantation, 2012, vol. 93, n° 7, p. 703-8. https://archive-ouverte.unige.ch/unige:28642