Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior

Niclauss, Nadja; Wojtusciszyn, Anne; Morel, Philippe; Demuylder-Mischler, Sandrine; Brault, Coralie; Parnaud, Géraldine; Ris, Frédéric; Bosco, Domenico; Badet, Lionel; Benhamou, Pierre-Yves; Berney, Thierry

doi:10.1097/TP.0b013e3182476cc8

Scientific article

English

Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior

ContributorsNiclauss, Nadja; Wojtusciszyn, Anne; Morel, Philippe; Demuylder-Mischler, Sandrine; Brault, Coralie; Parnaud, Géraldine; Ris, Frédéric; Bosco, Domenico; Badet, Lionel; Benhamou, Pierre-Yves; Berney, Thierry

Published inTransplantation, vol. 93, no. 7, p. 703-708

Publication date2012

Abstract

Institut Georges Lopez-1 (IGL-1) is a preservation solution similar to University of Wisconsin (UW) with reversed Na/K contents. In this study, we assessed the impact of IGL-1, UW, and Celsior (CS) solutions on islet isolation and transplant outcome.

Keywords

Adenosine/therapeutic use
Adult
Allopurinol/therapeutic use
Analysis of Variance
Biological Markers/blood
Blood Glucose/metabolism
C-Peptide/blood
Chi-Square Distribution
Diabetes Mellitus/blood/drug therapy/surgery
Disaccharides/therapeutic use
Electrolytes/therapeutic use
Female
Glutamates/therapeutic use
Glutathione/therapeutic use
Hemoglobin A, Glycosylated/metabolism
Histidine/therapeutic use
Humans
Hypoglycemic Agents/therapeutic use
Insulin/therapeutic use
Islets of Langerhans/drug effects/metabolism
Islets of Langerhans Transplantation
Male
Mannitol/therapeutic use
Middle Aged
Organ Preservation/methods
Organ Preservation Solutions/therapeutic use
Raffinose/therapeutic use
Retrospective Studies
Time Factors
Tissue Culture Techniques
Tissue and Organ Harvesting/methods
Treatment Outcome

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Citation (ISO format)

NICLAUSS, Nadja et al. Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior. In: Transplantation, 2012, vol. 93, n° 7, p. 703–708. doi: 10.1097/TP.0b013e3182476cc8

Article (Published version)

Identifiers

PID : unige:28642
DOI : 10.1097/TP.0b013e3182476cc8
PMID : 22343333

Journal ISSN0041-1337

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Comparative impact on islet isolation and transplant outcome of the preservation solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior

Institut Georges Lopez-1 (IGL-1) is a preservation solution similar to University of Wisconsin (UW) with reversed Na/K contents. In this study, we assessed the impact of IGL-1, UW, and Celsior (CS) solutions on islet isolation and transplant outcome.

Technical informations