Influence of donor age on islet isolation and transplantation outcome

Niclauss, Nadja; Bosco, Domenico; Morel, Philippe; Demuylder-Mischler, Sandrine; Brault, Coralie; Milliat-Guittard, Laure; Colin, Cyrille; Parnaud, Géraldine; Muller, Yannick; Giovannoni, Laurianne; Meier, Raphaël; Toso, Christian; Badet, Lionel; Benhamou, Pierre-Yves; Berney, Thierry

doi:10.1097/TP.0b013e31820385e6

Scientific article

Meta-analysis

English

Influence of donor age on islet isolation and transplantation outcome

ContributorsNiclauss, Nadja; Bosco, Domenico; Morel, Philippe; Demuylder-Mischler, Sandrine; Brault, Coralie; Milliat-Guittard, Laure; Colin, Cyrille; Parnaud, Géraldine; Muller, Yannick; Giovannoni, Laurianne; Meier, Raphaël; Toso, Christian

; Badet, Lionel; Benhamou, Pierre-Yves; Berney, Thierry

Published inTransplantation, vol. 91, no. 3, p. 360-366

Publication date2011

Abstract

It has been suggested that the age of human organ donors might influence islet isolation and transplantation outcome in a negative way due to a decrease of in vivo function in islets isolated from older donors.

Keywords

Adult
Age Factors
Blood Glucose/metabolism
Diabetes Mellitus, Type 1/drug therapy/surgery
Female
Humans
Hypoglycemic Agents/therapeutic use
Insulin/therapeutic use
Islets of Langerhans/physiology/surgery
Islets of Langerhans Transplantation/physiology
Male
Middle Aged
Retrospective Studies
Tissue Donors
Treatment Outcome

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Citation (ISO format)

NICLAUSS, Nadja et al. Influence of donor age on islet isolation and transplantation outcome. In: Transplantation, 2011, vol. 91, n° 3, p. 360–366. doi: 10.1097/TP.0b013e31820385e6

Article (Published version)

Identifiers

PID : unige:24934
DOI : 10.1097/TP.0b013e31820385e6
PMID : 21344706

Journal ISSN0041-1337

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Influence of donor age on islet isolation and transplantation outcome

It has been suggested that the age of human organ donors might influence islet isolation and transplantation outcome in a negative way due to a decrease of in vivo function in islets isolated from older donors.

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