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Title

Phylogenetic disparity influences the predominance of direct over indirect pathway of antigen presentation in islet xenotransplantation

Authors
Mathe, Z
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Published in Transplantation Proceedings. 2005, vol. 37, no. 1, p. 463-5
Abstract Cellular immunity plays a major role in rejection of xenografted islets. Depending on the phylogenetical disparity, direct or indirect antigen presentation is predominant. The aim of this study was to analyze in vitro the predominance of direct or indirect presentation, and in vivo the effect of macrophage depletion on concordant and discordant islet xenograft survival.
Keywords AnimalsAntigen Presentation/immunologyGraft Rejection/immunologyGraft Survival/immunologyHumansIslets of Langerhans Transplantation/immunologyLymphocyte Culture Test, MixedMaleMiceMice, Inbred C57BLPhylogenyRatsRats, Sprague-DawleyTime FactorsTransplantation, Heterologous/immunology
Identifiers
PMID: 15808677
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Structures
Research groups Transplantation et hépatologie (905)
Chirurgie viscérale (104)
La transplantation d'îlots de Langerhans (623)
Cultures cellulaires et transplantations (519)
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(ISO format)
ANDRES, Axel et al. Phylogenetic disparity influences the predominance of direct over indirect pathway of antigen presentation in islet xenotransplantation. In: Transplantation Proceedings, 2005, vol. 37, n° 1, p. 463-5. https://archive-ouverte.unige.ch/unige:39208

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Deposited on : 2014-08-06

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