| Relevance and limitations of clinical follow-up in a pharmacokinetic study on direct oral anticoagulants | Frontiers in pharmacology | | | 2026 | 24 | 46 |
|
| Cytochrome P450 phenotyping using the Geneva cocktail improves metabolic capacity prediction in a hospitalized patient population | British journal of clinical pharmacology | | | 2025 | 66 | 0 |
|
| Improving Understanding of Fexofenadine Pharmacokinetics to Assess Pgp Phenotypic Activity in Older Adult Patients Using Population Pharmacokinetic Modeling | Clinical pharmacokinetics | | | 2025 | 82 | 244 |
|
| The Impact of Dexamethasone and Prednisone on Apixaban and Rivaroxaban Exposure in COVID-19 Patients : A Physiologically Based Pharmacokinetic Modeling Study | Clinical pharmacology and therapeutics | | | 2025 | 83 | 587 |
|
| Molecular Profiling of SYT-SSX Fusion Transcripts for Enhanced Diagnosis of Synovial Sarcomas | Journal of personalized medicine | | | 2025 | 2 | 0 |
|
| Virtual twin approach using physiologically based pharmacokinetic modelling in hospitalized patients treated with apixaban or rivaroxaban | British journal of clinical pharmacology | | | 2025 | 97 | 1 |
|
| Simulation-Based Optimization of Sampling Schedules for Model-Informed Precision Dosing of Once-Daily and 4-Times-Daily Busulfan in Pediatric Patients | Therapeutic drug monitoring | | | 2024 | 27 | 161 |
|
| Application of Microwave-Assisted Method for Lutein Extraction from Pistachio Waste | Journal of nuts | | | 2024 | 125 | 600 |
|
| Guidance on selecting optimal steady-state tacrolimus concentrations for continuous IV perfusion : insights from physiologically based pharmacokinetic modeling | Pharmaceuticals | | | 2024 | 114 | 706 |
|
| Optimization of Lutein Extraction from Pistachio Waste Using Experimental Design and Ultrasonic Method | Waste and biomass valorization | | | 2024 | 122 | 0 |
|
| Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping | Journal of chromatography. B | | | 2024 | 119 | 178 |
|
| In vitro screening of UGT2B10 in silico prioritized putative ligands from drugs used in the pediatric hematopoietic stem cell transplantation setting | Pharmacology research & perspectives | | | 2024 | 112 | 193 |
|
| Practice of CYP450 genotyping and phenotyping in children in a real-life setting | Frontiers in pharmacology | | | 2023 | 91 | 275 |
|
| Phenotyping Indices of CYP450 and P-Glycoprotein in Human Volunteers and in Patients Treated with Painkillers or Psychotropic Drugs | Pharmaceutics | | | 2023 | 125 | 568 |
|
| Apixaban and rivaroxaban's physiologically-based pharmacokinetic model validation in hospitalized patients: A first step for larger use of a priori modeling approach at bed side | CPT: pharmacometrics & systems pharmacology | | | 2023 | 157 | 608 |
|
| Evaluation of important human CYP450 isoforms and P-glycoprotein phenotype changes and genotype in type 2 diabetic patients, before and after intensifying treatment regimen using Geneva cocktail | Basic & clinical pharmacology & toxicology | | | 2023 | 129 | 0 |
|
| Evaluation of Pupillometry for CYP2D6 Phenotyping in Children Treated with Tramadol | Pharmaceuticals | | | 2023 | 78 | 84 |
|
| Pharmacokinetic Modeling and Simulation with Pharmacogenetic Insights Support the Relevance of Therapeutic Drug Monitoring for Myeloablative Busulfan Dosing in Adult HSCT | Transplantation and cellular therapy | | | 2023 | 102 | 195 |
|
| Impact of obesity and bariatric surgery on metabolic enzymes and p-glycoprotein activity using the Geneva cocktail approach | Journal of personalized medicine | | | 2023 | 110 | 74 |
|
| Medical cannabinoids for painful symptoms in patients with severe dementia: a randomized, double-blind cross-over placebo-controlled trial protocol | Frontiers in pain research | | | 2023 | 139 | 377 |
|
| Population pharmacokinetics of apixaban in a real-life hospitalized population from the OptimAT study | CPT: pharmacometrics & systems pharmacology | | | 2023 | 145 | 546 |
|
| Joint Analysis of Phenotypic and Genomic Diversity Sheds Light on the Evolution of Xenobiotic Metabolism in Humans | Genome biology and evolution | | | 2022 | 549 | 466 |
|
| Editorial: Precision Medicine: Impact of Cytochromes P450 and Transporters Genetic Polymorphisms, Drug-Drug Interactions, Disease on Safety and Efficacy of Drugs | Frontiers in pharmacology | | | 2022 | 199 | 186 |
|
| Role of Drug Transporters in Elucidating Inter-Individual Variability in Pediatric Chemotherapy-Related Toxicities and Response | Pharmaceuticals | | | 2022 | 93 | 44 |
|
| Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots | Clinical and translational science | | | 2022 | 254 | 352 |
|
| Dexamethasone exposure in normal-weight and obese hospitalized COVID-19 patients: An observational exploratory trial | Clinical and translational science | | | 2022 | 167 | 214 |
|
| Impact of the Genotype and Phenotype of CYP3A and P-gp on the Apixaban and Rivaroxaban Exposure in a Real-World Setting | Journal of personalized medicine | | | 2022 | 236 | 474 |
|
| Case Report: Opioid Use Disorder Associated With Low/Moderate Dose of Loperamide in an Intellectual Disability Patient With CYP3A and P-Glycoprotein Reduced Activity | Frontiers in psychiatry | | | 2022 | 116 | 168 |
|
| Cannabinoids for behavioral symptoms in severe dementia: Safety and feasibility in a long-term pilot observational study in nineteen patients | Frontiers in aging neuroscience | | | 2022 | 98 | 334 |
|
| Population Pharmacokinetic Models for Direct Oral Anticoagulants: A Systematic Review and Clinical Appraisal Using Exposure Simulation | Clinical pharmacology and therapeutics | | | 2022 | 176 | 359 |
|
| Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics | CPT: pharmacometrics & systems pharmacology | | | 2022 | 313 | 550 |
|
| Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data | Journal of personalized medicine | | | 2022 | 79 | 743 |
|
| Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P-Glycoprotein Activities | Clinical pharmacology and therapeutics | | | 2022 | 192 | 413 |
|
| Personalized Medicine : Pharmacokinetics | Journal of personalized medicine | | | 2022 | 83 | 110 |
|
| Impact of SARS-CoV-2 Infection (COVID-19) on Cytochromes P450 Activity Assessed by the Geneva Cocktail | Clinical pharmacology and therapeutics | | | 2021 | 222 | 301 |
|
| Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice | ACS Nano | | | 2021 | 405 | 578 |
|
| Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy | Annual Review of Pharmacology and Toxicology | | | 2021 | 468 | 1 |
|
| Drug-drug interactions with direct oral anticoagulants: practical recommendations for clinicians | The American journal of medicine | | | 2021 | 190 | 0 |
|
| Mixing Drugs and Genetics: A Complex Hemorrhagic Cocktail | American Journal of Medicine | | | 2021 | 298 | 5 |
|
| CYP450 Genotype-Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting | Frontiers in pharmacology | | | 2021 | 293 | 446 |
|
| The 1β-Hydroxy-Deoxycholic Acid to Deoxycholic Acid Urinary Metabolic Ratio: Toward a Phenotyping of CYP3A Using an Endogenous Marker? | Journal of personalized medicine | | | 2021 | 235 | 76 |
|
| Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity | British journal of pharmacology | | | 2021 | 340 | 346 |
|
| The tyrosine kinase inhibitor nilotinib inhibits SARS‐CoV‐2 in vitro | Basic & Clinical Pharmacology & Toxicology | | | 2021 | 252 | 2 |
|
| Simultaneous determination of melatonin and 6-hydroxymelatonin in human overnight urine by LC-MS/MS | Journal of chromatography. B | | | 2021 | 446 | 849 |
|
| Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data | Journal of personalized medicine | | | 2021 | 184 | 112 |
|
| Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends | Frontiers in pharmacology | | | 2021 | 194 | 471 |
|
| Precision dosing of intravenous busulfan in pediatric hematopoietic stem cell transplantation: Results from a multicenter population pharmacokinetic study | CPT: pharmacometrics & systems pharmacology | | | 2021 | 258 | 291 |
|
| Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment | Molecular Oncology | | | 2020 | 450 | 208 |
|
| Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis | British Journal of Clinical Pharmacology | | | 2020 | 243 | 233 |
|
| Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic Origins | Drug Safety | | | 2020 | 747 | 719 |
|
| Impact of acute inflammation on cytochromes P450 activity assessed by the Geneva Cocktail | Clinical Pharmacology and Therapeutics | | | 2020 | 347 | 682 |
|
| GABAergic modulation of secondary hyperalgesia: A randomized controlled 4-way crossover trial with the α2-subunit preferring GABA positive allosteric modulator, N-desmethyl-clobazam in healthy volunteers | European Journal of Pain | | | 2020 | 273 | 1 |
|
| Bioavailability of Vortioxetine After a Roux-en-Y Gastric Bypass | Obesity Surgery | | | 2020 | 277 | 1 |
|
| Deep proteomics and phosphoproteomics reveal novel biological pathways perturbed by morphine, morphine-3-glucuronide and morphine-6-glucuronide in human astrocytes | Journal of Neuroscience Research | | | 2020 | 325 | 2 |
|
| Modern approaches for the phenotyping of cytochrome P450 enzymes in children | Expert Review of Clinical Pharmacology | | | 2020 | 225 | 1 |
|
| Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children | Therapeutic Drug Monitoring | | | 2020 | 463 | 266 |
|
| Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients | Journal of Thrombosis and Haemostasis | | | 2020 | 303 | 1 |
|
| Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study | Journal of Personalized Medicine | | | 2020 | 367 | 157 |
|
| Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail | Journal of Personalized Medicine | | | 2019 | 488 | 430 |
|
| Phenotyping of human CYP450 enzymes by endobiotics: current knowledge and methodological approaches | Clinical Pharmacokinetics | | | 2019 | 435 | 3 |
|
| Variables of interest to predict glomerular filtration rate in preterm newborns in the first days of life | Pediatric Nephrology | | | 2019 | 404 | 1 |
|
| Towards personalized antithrombotic treatments: focus on P2Y12 inhibitors and direct oral anticoagulants | Clinical Pharmacokinetics | | | 2019 | 515 | 2 |
|
| Drug-induced expression of the RNA-binding protein HuR attenuates the adaptive response to BRAF inhibition in melanoma | Biochemical and Biophysical Research Communications | | | 2019 | 393 | 281 |
|
| Liquid Chromatography-Tandem Mass Spectrometry Method for Ticagrelor and its Active Metabolite Determination in Human Plasma: Application to a Pharmacokinetic Study | Current Analytical Chemistry | | | 2019 | 485 | 1 |
|
| CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver content | Surgery for Obesity and Related Diseases | | | 2019 | 376 | 0 |
|
| Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins | Basic & Clinical Pharmacology & Toxicology | | | 2019 | 480 | 4 |
|
| Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer Treatment | Integrative Cancer Therapies | | | 2019 | 398 | 151 |
|
| Physiologically-based pharmacokinetic modeling for the prediction of CYP2D6-mediated gene-drug-drug interactions | CPT: pharmacometrics & systems pharmacology | | | 2019 | 422 | 641 |
|
| Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled study | European Journal of Pain | | | 2019 | 409 | 2 |
|
| Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling | Pediatric Research | | | 2019 | 344 | 2 |
|
| Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites | Clinical Pharmacokinetics | | | 2018 | 751 | 972 |
|
| Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives | Clinical Pharmacokinetics | | | 2018 | 534 | 1,250 |
|
| Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory Setting | Journal of Clinical Psychiatry | | | 2018 | 500 | 0 |
|
| Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software | Biopharmaceutics & Drug Disposition | | | 2018 | 638 | 12 |
|
| Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomes | Basic & Clinical Pharmacology & Toxicology | | | 2018 | 523 | 1,148 |
|
| Therapeutic Drug Monitoring of Busulfan for the Management of Pediatric Patients: Cross-Validation of Methods and Long-Term Performance | Therapeutic Drug Monitoring | | | 2018 | 877 | 952 |
|
| Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report | European Journal of Anaesthesiology | | | 2018 | 457 | 478 |
|
| Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study) | BMC Pharmacology & Toxicology | | | 2017 | 530 | 233 |
|
| Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactions | Clinical Pharmacology and Therapeutics | | | 2017 | 506 | 5 |
|
| Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases | Journal of pharmaceutical and biomedical analysis | | | 2017 | 684 | 1,191 |
|
| Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study | Pharmacological research | | | 2017 | 674 | 211 |
|
| Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future | Clinical Pharmacology and Therapeutics | | | 2017 | 611 | 0 |
|
| The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell Transplantation | Frontiers in Pharmacology | | | 2017 | 632 | 306 |
|
| Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane Transporters | Basic & clinical pharmacology & toxicology | | | 2017 | 556 | 3 |
|
| Plasma concentrations of transdermal fentanyl and buprenorphine in pigs (Sus scrofa domesticus) | Veterinary Anaesthesia and Analgesia | | | 2017 | 491 | 1 |
|
| Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine | Journal of Pharmaceutical Sciences | | | 2017 | 507 | 0 |
|
| Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis | Free radical biology & medicine | | | 2016 | 685 | 316 |
|
| An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure | Toxicology and applied pharmacology | | | 2016 | 657 | 2 |
|
| Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect | Frontiers in pharmacology | | | 2016 | 521 | 289 |
|
| The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia | Neuropharmacology | | | 2016 | 609 | 372 |
|
| Detection of busulfan adducts on proteins | RCM. Rapid communications in mass spectrometry | | | 2016 | 688 | 451 |
|
| Aspirin response: Differences in serum thromboxane B2 levels between clinical studies | Platelets | | | 2016 | 729 | 1 |
|
| Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach | Clinical pharmacology and therapeutics | | | 2016 | 683 | 1,112 |
|
| Pharmacogenomics of Oral Antithrombotic Drugs | Current pharmaceutical design | | | 2016 | 637 | 0 |
|
| Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells | Fundamental & clinical pharmacology | | | 2016 | 644 | 21 |
|
| Severe Vincristine-Induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study | Clinical therapeutics | | | 2016 | 567 | 2 |
|
| Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method | Basic & clinical pharmacology & toxicology | | | 2016 | 692 | 1,044 |
|
| Markers of Individual Drug Metabolism: Towards the Development of a Personalized Antidepressant Prescription | Current drug metabolism | | | 2015 | 599 | 3 |
|
| Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review | Current drug metabolism | | | 2015 | 658 | 6 |
|
| Augmented renal clearance, low ß-lactam concentrations and clinical outcomes in the critically ill: An observational prospective cohort study | International journal of antimicrobial agents | | | 2015 | 848 | 3 |
|
| GABAergic modulation in central sensitization in humans: a randomized placebo-controlled pharmacokinetic-pharmacodynamic study comparing clobazam with clonazepam in healthy volunteers | Pain | | | 2015 | 638 | 3 |
|
| Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a review | Current drug metabolism | | | 2014 | 670 | 0 |
|
| Incorporation of Flurbiprofen in a 4-Drug Cytochrome P450 Phenotyping Cocktail | Basic & clinical pharmacology & toxicology | | | 2014 | 661 | 4 |
|
| Phenotyping of CYP450 in human liver microsomes using the cocktail approach | Analytical & bioanalytical chemistry | | | 2014 | 552 | 2 |
|
| Antiplatelet Therapy: Targeting the TxA2 Pathway | Journal of cardiovascular translational research | | | 2014 | 666 | 2 |
|
| Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spots | Clinical pharmacology and therapeutics | | | 2014 | 939 | 729 |
|
| Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity | AIDS research and therapy | | | 2014 | 754 | 1,003 |
|
| The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation | Pharmacogenomics journal | | | 2014 | 754 | 8 |
|
| Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic Model | CPT: pharmacometrics & systems pharmacology | | | 2014 | 694 | 329 |
|
| Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma | Bioanalysis | | | 2014 | 780 | 5 |
|
| Role of paraoxonase-1 in CYP2C19 loss-of-function carriers | Thrombosis research | | | 2014 | 687 | 0 |
|
| A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies | Journal of pharmaceutical and biomedical analysis | | | 2014 | 595 | 7 |
|
| Antihyperalgesic Effect of the GABA(A) Ligand Clobazam in a Neuropathic Pain Model in Mice: A Pharmacokinetic-Pharmacodynamic Study | Basic & clinical pharmacology & toxicology | | | 2013 | 662 | 515 |
|
| Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties | Arteriosclerosis, thrombosis, and vascular biology | | | 2013 | 679 | 0 |
|
| Role of P-glycoprotein in the uptake/efflux transport of oral vitamin K antagonists and rivaroxaban through the Caco-2 cell model | Basic & clinical pharmacology & toxicology | | | 2013 | 615 | 3 |
|
| Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model | The journal of antimicrobial chemotherapy | | | 2013 | 601 | 0 |
|
| Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers | Basic & clinical pharmacology & toxicology | | | 2013 | 675 | 471 |
|
| Dual reuptake inhibitor milnacipran and spinal pain pathways in fibromyalgia patients: a randomized, double-blind, placebo-controlled trial | Pain physician | | | 2013 | 639 | 1,179 |
|
| Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute pain | Pain physician | | | 2013 | 810 | 815 |
|
| Applications of CYP450 Testing in the Clinical Setting | Molecular diagnosis & therapy | | | 2013 | 784 | 1,132 |
|
| Evidence of Drug-Drug Interactions through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications for Cellular Concentrations of Competing Drugs | Drug metabolism and disposition | | | 2013 | 827 | 792 |
|
| NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion | Diabetes | | | 2012 | 832 | 620 |
|
| Transcriptional regulation of CYP2C19 and its role in altered enzyme activity | Current drug metabolism | | | 2012 | 623 | 0 |
|
| Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patient | AIDS | | | 2012 | 650 | 730 |
|
| Validation of the simplified UVB model to assess the pharmacodynamics of analgesics in healthy human volunteers | Chimia | | | 2012 | 818 | 1,207 |
|
| Pharmacokinetic-pharmacodynamic modelling of opioids in healthy human volunteers. A minireview | Basic & clinical pharmacology & toxicology | | | 2012 | 668 | 881 |
|
| Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis | Journal of thrombosis and haemostasis | | | 2012 | 637 | 0 |
|
| The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro | British journal of pharmacology | | | 2012 | 605 | 0 |
|
| Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot | Clinical pharmacology and therapeutics | | | 2012 | 667 | 0 |
|
| Analgesics in patients with hepatic impairment: pharmacology and clinical implications | Drugs | | | 2012 | 719 | 3 |
|
| Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection | Journal of viral hepatitis | | | 2012 | 675 | 0 |
|
| A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometry | RCM. Rapid communications in mass spectrometry | | | 2012 | 860 | 1,032 |
|
| A randomized, controlled trial validates a peripheral supra-additive antihyperalgesic effect of a paracetamol-ketorolac combination | Basic & clinical pharmacology & toxicology | | | 2011 | 691 | 0 |
|
| Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients | Metabolism, clinical and experimental | | | 2011 | 703 | 0 |
|
| HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain | Neuropharmacology | | | 2011 | 832 | 761 |
|
| How organic anions accumulate in hepatocytes lacking Mrp2: evidence in rat liver | The Journal of pharmacology and experimental therapeutics | | | 2011 | 649 | 0 |
|
| Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite | Journal of pharmaceutical and biomedical analysis | | | 2011 | 757 | 1,041 |
|
| Two structurally different T-type Ca2+ channel inhibitors, mibefradil and pimozide, protect CA1 neurons from delayed death after global ischemia in rats | Fundamental & clinical pharmacology | | | 2011 | 31 | 0 |
|
| The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone | British journal of pharmacology | | | 2010 | 890 | 2 |
|
| Impact of genetic polymorphisms and drug-drug interactions on clopidogrel and prasugrel response variability | Current drug metabolism | | | 2010 | 686 | 0 |
|
| Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety | British journal of pharmacology | | | 2010 | 667 | 1 |
|
| Uptake/efflux transport of tramadol enantiomers and O-desmethyl-tramadol: focus on P-glycoprotein | Basic & clinical pharmacology & toxicology | | | 2009 | 655 | 2 |
|
| Two-dimensional liquid chromatography-ion trap mass spectrometry for the simultaneous determination of ketorolac enantiomers and paracetamol in human plasma: application to a pharmacokinetic study | Journal of chromatography | | | 2009 | 576 | 0 |
|
| The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction | Pharmacogenomics journal | | | 2009 | 928 | 0 |
|
| P-glycoprotein is not involved in the differential oral potency of naloxone and naltrexone | Fundamental & clinical pharmacology | | | 2009 | 690 | 0 |
|
| Influence of ABCB1 gene polymorphisms and P-glycoprotein activity on cyclosporine pharmacokinetics in peripheral blood mononuclear cells in healthy volunteers | Drug metabolism letters | | | 2008 | 874 | 0 |
|
| Lack of interaction of the NMDA receptor antagonists dextromethorphan and dextrorphan with P-glycoprotein | Current drug metabolism | | | 2008 | 670 | 4 |
|
| Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients | Journal of chromatography. B | | | 2008 | 640 | 4 |
|
| Pharmacokinetic and pharmacodynamic properties of buprenorphine after a single intravenous administration in healthy volunteers: a randomized, double-blind, placebo-controlled, crossover study | Clinical therapeutics | | | 2007 | 784 | 0 |
|
| Development and validation of a new reversed-phase ion pairing liquid chromatographic method with fluorescence detection for penciclovir analysis in plasma and aqueous humor | Journal of chromatography. B | | | 2005 | 626 | 2 |
|
| Codeine intoxication associated with ultrarapid CYP2D6 metabolism | The New England journal of medicine | | | 2004 | 573 | 1 |
|
| High performance liquid chromatography of acarbose and its metabolite on porous graphitic carbon column | Journal of separation science | | | 2002 | 961 | 1 |
|
| Simultaneous analysis of polyhydroxylated alkaloids by capillary electrophoresis using borate complexation and evaluation of sweeping technique for sensitivity improvement | Chromatographia | | | 2002 | 667 | 1 |
|
| Calystegine distribution in some solanaceous species | Phytochemistry | | | 2001 | 658 | 0 |
|
| Capillary electrophoresis and high-performance anion exchange chromatography for monitoring caseinoglycomacropeptide sialylation | Journal of pharmaceutical and biomedical analysis | | | 2001 | 585 | 0 |
|
| Routine o-glycan characterization in nutritional supplements--a comparison of analytical methods for the monitoring of the bovine kappa-casein macropeptide glycosylation | Journal of chromatography | | | 2001 | 641 | 0 |
|
| Use of borate complexation for the separation of non-UV-absorbing calystegines by capillary electrophoresis | Journal of chromatography | | | 2000 | 663 | 0 |
|
| Partial solubility parameters of lactose, mannitol and saccharose using the modified extended Hansen method and evaporation light scattering detection | Chemical and pharmaceutical bulletin | | | 2000 | 588 | 0 |
|
| Experimental design for enantioselective separation of celiprolol by capillary electrophoresis using sulfated beta-cyclodextrin | Electrophoresis | | | 1999 | 644 | 2 |
|
| Development and validation of liquid chromatography and capillary electrophoresis methods for acarbose determination in pharmaceutical tablets | Journal of pharmaceutical and biomedical analysis | | | 1998 | 648 | 0 |
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