YD
Daali, Youssef
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Improving Understanding of Fexofenadine Pharmacokinetics to Assess Pgp Phenotypic Activity in Older Adult Patients Using Population Pharmacokinetic Modeling | Clinical pharmacokinetics | 2025 | 11 | 3 | |||
The Impact of Dexamethasone and Prednisone on Apixaban and Rivaroxaban Exposure in COVID-19 Patients : A Physiologically Based Pharmacokinetic Modeling Study | Clinical pharmacology & therapeutics | 2025 | 15 | 13 | |||
Application of Microwave-Assisted Method for Lutein Extraction from Pistachio Waste | Journal of nuts | 2024 | 52 | 84 | |||
Guidance on selecting optimal steady-state tacrolimus concentrations for continuous IV perfusion : insights from physiologically based pharmacokinetic modeling | Pharmaceuticals | 2024 | 46 | 22 | |||
Optimization of Lutein Extraction from Pistachio Waste Using Experimental Design and Ultrasonic Method | Waste and biomass valorization | 2024 | 55 | 0 | |||
Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping | Journal of chromatography. B | 2024 | 56 | 47 | |||
In vitro screening of UGT2B10 in silico prioritized putative ligands from drugs used in the pediatric hematopoietic stem cell transplantation setting | Pharmacology research & perspectives | 2024 | 17 | 7 | |||
Practice of CYP450 genotyping and phenotyping in children in a real-life setting | Frontiers in pharmacology | 2023 | 40 | 35 | |||
Phenotyping Indices of CYP450 and P-Glycoprotein in Human Volunteers and in Patients Treated with Painkillers or Psychotropic Drugs | Pharmaceutics | 2023 | 82 | 57 | |||
Apixaban and rivaroxaban's physiologically-based pharmacokinetic model validation in hospitalized patients: A first step for larger use of a priori modeling approach at bed side | CPT: pharmacometrics & systems pharmacology | 2023 | 107 | 82 | |||
Evaluation of important human CYP450 isoforms and P-glycoprotein phenotype changes and genotype in type 2 diabetic patients, before and after intensifying treatment regimen using Geneva cocktail | Basic & clinical pharmacology & toxicology | 2023 | 54 | 0 | |||
Evaluation of Pupillometry for CYP2D6 Phenotyping in Children Treated with Tramadol | Pharmaceuticals | 2023 | 40 | 15 | |||
Pharmacokinetic Modeling and Simulation with Pharmacogenetic Insights Support the Relevance of Therapeutic Drug Monitoring for Myeloablative Busulfan Dosing in Adult HSCT | Transplantation and cellular therapy | 2023 | 50 | 47 | |||
Impact of obesity and bariatric surgery on metabolic enzymes and p-glycoprotein activity using the Geneva cocktail approach | Journal of personalized medicine | 2023 | 54 | 10 | |||
Medical cannabinoids for painful symptoms in patients with severe dementia: a randomized, double-blind cross-over placebo-controlled trial protocol | Frontiers in pain research | 2023 | 83 | 21 | |||
Population pharmacokinetics of apixaban in a real-life hospitalized population from the OptimAT study | CPT: pharmacometrics & systems pharmacology | 2023 | 63 | 51 | |||
Joint Analysis of Phenotypic and Genomic Diversity Sheds Light on the Evolution of Xenobiotic Metabolism in Humans | Genome biology and evolution | 2022 | 359 | 58 | |||
Editorial: Precision Medicine: Impact of Cytochromes P450 and Transporters Genetic Polymorphisms, Drug-Drug Interactions, Disease on Safety and Efficacy of Drugs | Frontiers in pharmacology | 2022 | 153 | 99 | |||
Role of Drug Transporters in Elucidating Inter-Individual Variability in Pediatric Chemotherapy-Related Toxicities and Response | Pharmaceuticals | 2022 | 56 | 15 | |||
Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots | Clinical and translational science | 2022 | 191 | 73 | |||
Dexamethasone exposure in normal-weight and obese hospitalized COVID-19 patients: An observational exploratory trial | Clinical and translational science | 2022 | 109 | 57 | |||
Impact of the Genotype and Phenotype of CYP3A and P-gp on the Apixaban and Rivaroxaban Exposure in a Real-World Setting | Journal of personalized medicine | 2022 | 175 | 141 | |||
Case Report: Opioid Use Disorder Associated With Low/Moderate Dose of Loperamide in an Intellectual Disability Patient With CYP3A and P-Glycoprotein Reduced Activity | Frontiers in psychiatry | 2022 | 43 | 58 | |||
Cannabinoids for behavioral symptoms in severe dementia: Safety and feasibility in a long-term pilot observational study in nineteen patients | Frontiers in aging neuroscience | 2022 | 66 | 22 | |||
Population Pharmacokinetic Models for Direct Oral Anticoagulants: A Systematic Review and Clinical Appraisal Using Exposure Simulation | Clinical pharmacology and therapeutics | 2022 | 115 | 118 | |||
Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics | CPT: pharmacometrics & systems pharmacology | 2022 | 211 | 281 | |||
Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data | Journal of personalized medicine | 2022 | 41 | 29 | |||
Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P-Glycoprotein Activities | Clinical pharmacology & therapeutics | 2022 | 130 | 252 | |||
Personalized Medicine : Pharmacokinetics | Journal of personalized medicine | 2022 | 30 | 10 | |||
Impact of SARS-CoV-2 Infection (COVID-19) on Cytochromes P450 Activity Assessed by the Geneva Cocktail | Clinical pharmacology and therapeutics | 2021 | 162 | 82 | |||
Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice | ACS Nano | 2021 | 318 | 452 | |||
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy | Annual Review of Pharmacology and Toxicology | 2021 | 308 | 1 | |||
Drug-drug interactions with direct oral anticoagulants: practical recommendations for clinicians | The American journal of medicine | 2021 | 124 | 0 | |||
Mixing Drugs and Genetics: A Complex Hemorrhagic Cocktail | American Journal of Medicine | 2021 | 239 | 5 | |||
CYP450 Genotype-Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting | Frontiers in pharmacology | 2021 | 222 | 102 | |||
The 1β-Hydroxy-Deoxycholic Acid to Deoxycholic Acid Urinary Metabolic Ratio: Toward a Phenotyping of CYP3A Using an Endogenous Marker? | Journal of personalized medicine | 2021 | 180 | 42 | |||
Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity | British journal of pharmacology | 2021 | 265 | 110 | |||
The tyrosine kinase inhibitor nilotinib inhibits SARS‐CoV‐2 in vitro | Basic & Clinical Pharmacology & Toxicology | 2021 | 189 | 2 | |||
Simultaneous determination of melatonin and 6-hydroxymelatonin in human overnight urine by LC-MS/MS | Journal of chromatography. B | 2021 | 311 | 279 | |||
Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data | Journal of personalized medicine | 2021 | 141 | 62 | |||
Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends | Frontiers in pharmacology | 2021 | 131 | 134 | |||
Precision dosing of intravenous busulfan in pediatric hematopoietic stem cell transplantation: Results from a multicenter population pharmacokinetic study | CPT: pharmacometrics & systems pharmacology | 2021 | 204 | 94 | |||
Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment | Molecular Oncology | 2020 | 384 | 159 | |||
Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis | British Journal of Clinical Pharmacology | 2020 | 187 | 124 | |||
Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic Origins | Drug Safety | 2020 | 553 | 153 | |||
Impact of acute inflammation on cytochromes P450 activity assessed by the Geneva Cocktail | Clinical Pharmacology and Therapeutics | 2020 | 278 | 345 | |||
GABAergic modulation of secondary hyperalgesia: A randomized controlled 4-way crossover trial with the α2-subunit preferring GABA positive allosteric modulator, N-desmethyl-clobazam in healthy volunteers | European Journal of Pain | 2020 | 221 | 1 | |||
Bioavailability of Vortioxetine After a Roux-en-Y Gastric Bypass | Obesity Surgery | 2020 | 230 | 1 | |||
Deep proteomics and phosphoproteomics reveal novel biological pathways perturbed by morphine, morphine-3-glucuronide and morphine-6-glucuronide in human astrocytes | Journal of Neuroscience Research | 2020 | 267 | 2 | |||
Modern approaches for the phenotyping of cytochrome P450 enzymes in children | Expert Review of Clinical Pharmacology | 2020 | 167 | 1 | |||
Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children | Therapeutic Drug Monitoring | 2020 | 374 | 143 | |||
Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients | Journal of Thrombosis and Haemostasis | 2020 | 237 | 1 | |||
Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study | Journal of Personalized Medicine | 2020 | 314 | 80 | |||
Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail | Journal of Personalized Medicine | 2019 | 352 | 163 | |||
Phenotyping of human CYP450 enzymes by endobiotics: current knowledge and methodological approaches | Clinical Pharmacokinetics | 2019 | 354 | 3 | |||
Variables of interest to predict glomerular filtration rate in preterm newborns in the first days of life | Pediatric Nephrology | 2019 | 349 | 1 | |||
Towards personalized antithrombotic treatments: focus on P2Y12 inhibitors and direct oral anticoagulants | Clinical Pharmacokinetics | 2019 | 439 | 2 | |||
Drug-induced expression of the RNA-binding protein HuR attenuates the adaptive response to BRAF inhibition in melanoma | Biochemical and Biophysical Research Communications | 2019 | 335 | 230 | |||
Liquid Chromatography-Tandem Mass Spectrometry Method for Ticagrelor and its Active Metabolite Determination in Human Plasma: Application to a Pharmacokinetic Study | Current Analytical Chemistry | 2019 | 340 | 1 | |||
CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver content | Surgery for Obesity and Related Diseases | 2019 | 320 | 0 | |||
Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins | Basic & Clinical Pharmacology & Toxicology | 2019 | 406 | 4 | |||
Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer Treatment | Integrative Cancer Therapies | 2019 | 334 | 112 | |||
Physiologically-based pharmacokinetic modeling for the prediction of CYP2D6-mediated gene-drug-drug interactions | CPT: pharmacometrics & systems pharmacology | 2019 | 354 | 207 | |||
Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled study | European Journal of Pain | 2019 | 340 | 2 | |||
Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling | Pediatric Research | 2019 | 286 | 2 | |||
Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites | Clinical Pharmacokinetics | 2018 | 604 | 630 | |||
Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives | Clinical Pharmacokinetics | 2018 | 472 | 632 | |||
Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory Setting | Journal of Clinical Psychiatry | 2018 | 453 | 0 | |||
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software | Biopharmaceutics & Drug Disposition | 2018 | 580 | 12 | |||
Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomes | Basic & Clinical Pharmacology & Toxicology | 2018 | 455 | 366 | |||
Therapeutic Drug Monitoring of Busulfan for the Management of Pediatric Patients: Cross-Validation of Methods and Long-Term Performance | Therapeutic Drug Monitoring | 2018 | 808 | 428 | |||
Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report | European Journal of Anaesthesiology | 2018 | 404 | 242 | |||
Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study) | BMC Pharmacology & Toxicology | 2017 | 449 | 167 | |||
Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactions | Clinical Pharmacology and Therapeutics | 2017 | 461 | 5 | |||
Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases | Journal of pharmaceutical and biomedical analysis | 2017 | 597 | 571 | |||
Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study | Pharmacological research | 2017 | 615 | 157 | |||
Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future | Clinical Pharmacology and Therapeutics | 2017 | 533 | 0 | |||
The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell Transplantation | Frontiers in Pharmacology | 2017 | 554 | 221 | |||
Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane Transporters | Basic & clinical pharmacology & toxicology | 2017 | 507 | 3 | |||
Plasma concentrations of transdermal fentanyl and buprenorphine in pigs (Sus scrofa domesticus) | Veterinary Anaesthesia and Analgesia | 2017 | 441 | 1 | |||
Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine | Journal of Pharmaceutical Sciences | 2017 | 435 | 0 | |||
Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis | Free radical biology & medicine | 2016 | 636 | 249 | |||
An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure | Toxicology and applied pharmacology | 2016 | 582 | 2 | |||
Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect | Frontiers in pharmacology | 2016 | 439 | 208 | |||
The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia | Neuropharmacology | 2016 | 533 | 286 | |||
Detection of busulfan adducts on proteins | RCM. Rapid communications in mass spectrometry | 2016 | 607 | 124 | |||
Aspirin response: Differences in serum thromboxane B2 levels between clinical studies | Platelets | 2016 | 674 | 1 | |||
Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach | Clinical pharmacology and therapeutics | 2016 | 593 | 646 | |||
Pharmacogenomics of Oral Antithrombotic Drugs | Current pharmaceutical design | 2016 | 583 | 0 | |||
Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells | Fundamental & clinical pharmacology | 2016 | 569 | 21 | |||
Severe Vincristine-Induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study | Clinical therapeutics | 2016 | 515 | 2 | |||
Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method | Basic & clinical pharmacology & toxicology | 2016 | 622 | 374 | |||
Markers of Individual Drug Metabolism: Towards the Development of a Personalized Antidepressant Prescription | Current drug metabolism | 2015 | 557 | 3 | |||
Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review | Current drug metabolism | 2015 | 607 | 6 | |||
Augmented renal clearance, low ß-lactam concentrations and clinical outcomes in the critically ill: An observational prospective cohort study | International journal of antimicrobial agents | 2015 | 768 | 3 | |||
GABAergic modulation in central sensitization in humans: a randomized placebo-controlled pharmacokinetic-pharmacodynamic study comparing clobazam with clonazepam in healthy volunteers | Pain | 2015 | 576 | 3 | |||
Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a review | Current drug metabolism | 2014 | 622 | 0 | |||
Incorporation of Flurbiprofen in a 4-Drug Cytochrome P450 Phenotyping Cocktail | Basic & clinical pharmacology & toxicology | 2014 | 616 | 4 | |||
Phenotyping of CYP450 in human liver microsomes using the cocktail approach | Analytical & bioanalytical chemistry | 2014 | 477 | 2 | |||
Antiplatelet Therapy: Targeting the TxA2 Pathway | Journal of cardiovascular translational research | 2014 | 595 | 2 | |||
Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spots | Clinical pharmacology and therapeutics | 2014 | 833 | 334 | |||
Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity | AIDS research and therapy | 2014 | 659 | 914 | |||
The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation | Pharmacogenomics journal | 2014 | 632 | 8 | |||
Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic Model | CPT: pharmacometrics & systems pharmacology | 2014 | 578 | 229 | |||
Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma | Bioanalysis | 2014 | 712 | 5 | |||
Role of paraoxonase-1 in CYP2C19 loss-of-function carriers | Thrombosis research | 2014 | 635 | 0 | |||
A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies | Journal of pharmaceutical and biomedical analysis | 2014 | 517 | 7 | |||
Antihyperalgesic Effect of the GABA(A) Ligand Clobazam in a Neuropathic Pain Model in Mice: A Pharmacokinetic-Pharmacodynamic Study | Basic & clinical pharmacology & toxicology | 2013 | 608 | 334 | |||
Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties | Arteriosclerosis, thrombosis, and vascular biology | 2013 | 618 | 0 | |||
Role of P-glycoprotein in the uptake/efflux transport of oral vitamin K antagonists and rivaroxaban through the Caco-2 cell model | Basic & clinical pharmacology & toxicology | 2013 | 547 | 3 | |||
Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model | The journal of antimicrobial chemotherapy | 2013 | 547 | 0 | |||
Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers | Basic & clinical pharmacology & toxicology | 2013 | 590 | 379 | |||
Dual reuptake inhibitor milnacipran and spinal pain pathways in fibromyalgia patients: a randomized, double-blind, placebo-controlled trial | Pain physician | 2013 | 574 | 1,039 | |||
Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute pain | Pain physician | 2013 | 728 | 638 | |||
Applications of CYP450 Testing in the Clinical Setting | Molecular diagnosis & therapy | 2013 | 654 | 792 | |||
Evidence of Drug-Drug Interactions through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications for Cellular Concentrations of Competing Drugs | Drug metabolism and disposition | 2013 | 765 | 628 | |||
NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion | Diabetes | 2012 | 753 | 477 | |||
Transcriptional regulation of CYP2C19 and its role in altered enzyme activity | Current drug metabolism | 2012 | 548 | 0 | |||
Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patient | AIDS | 2012 | 582 | 516 | |||
Validation of the simplified UVB model to assess the pharmacodynamics of analgesics in healthy human volunteers | Chimia | 2012 | 762 | 1,124 | |||
Pharmacokinetic-pharmacodynamic modelling of opioids in healthy human volunteers. A minireview | Basic & clinical pharmacology & toxicology | 2012 | 579 | 610 | |||
Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis | Journal of thrombosis and haemostasis | 2012 | 580 | 0 | |||
The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro | British journal of pharmacology | 2012 | 529 | 0 | |||
Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot | Clinical pharmacology and therapeutics | 2012 | 596 | 0 | |||
Analgesics in patients with hepatic impairment: pharmacology and clinical implications | Drugs | 2012 | 663 | 3 | |||
Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection | Journal of viral hepatitis | 2012 | 622 | 0 | |||
A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometry | RCM. Rapid communications in mass spectrometry | 2012 | 771 | 757 | |||
A randomized, controlled trial validates a peripheral supra-additive antihyperalgesic effect of a paracetamol-ketorolac combination | Basic & clinical pharmacology & toxicology | 2011 | 645 | 0 | |||
Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients | Metabolism, clinical and experimental | 2011 | 616 | 0 | |||
HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain | Neuropharmacology | 2011 | 745 | 565 | |||
How organic anions accumulate in hepatocytes lacking Mrp2: evidence in rat liver | The Journal of pharmacology and experimental therapeutics | 2011 | 587 | 0 | |||
Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite | Journal of pharmaceutical and biomedical analysis | 2011 | 693 | 739 | |||
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone | British journal of pharmacology | 2010 | 728 | 2 | |||
Impact of genetic polymorphisms and drug-drug interactions on clopidogrel and prasugrel response variability | Current drug metabolism | 2010 | 629 | 0 | |||
Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety | British journal of pharmacology | 2010 | 572 | 1 | |||
Uptake/efflux transport of tramadol enantiomers and O-desmethyl-tramadol: focus on P-glycoprotein | Basic & clinical pharmacology & toxicology | 2009 | 591 | 2 | |||
Two-dimensional liquid chromatography-ion trap mass spectrometry for the simultaneous determination of ketorolac enantiomers and paracetamol in human plasma: application to a pharmacokinetic study | Journal of chromatography | 2009 | 514 | 0 | |||
The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction | Pharmacogenomics journal | 2009 | 815 | 0 | |||
P-glycoprotein is not involved in the differential oral potency of naloxone and naltrexone | Fundamental & clinical pharmacology | 2009 | 620 | 0 | |||
Influence of ABCB1 gene polymorphisms and P-glycoprotein activity on cyclosporine pharmacokinetics in peripheral blood mononuclear cells in healthy volunteers | Drug metabolism letters | 2008 | 742 | 0 | |||
Lack of interaction of the NMDA receptor antagonists dextromethorphan and dextrorphan with P-glycoprotein | Current drug metabolism | 2008 | 618 | 4 | |||
Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients | Journal of chromatography. B | 2008 | 575 | 4 | |||
Pharmacokinetic and pharmacodynamic properties of buprenorphine after a single intravenous administration in healthy volunteers: a randomized, double-blind, placebo-controlled, crossover study | Clinical therapeutics | 2007 | 699 | 0 | |||
Development and validation of a new reversed-phase ion pairing liquid chromatographic method with fluorescence detection for penciclovir analysis in plasma and aqueous humor | Journal of chromatography. B | 2005 | 550 | 2 | |||
Codeine intoxication associated with ultrarapid CYP2D6 metabolism | The New England journal of medicine | 2004 | 508 | 1 | |||
High performance liquid chromatography of acarbose and its metabolite on porous graphitic carbon column | Journal of separation science | 2002 | 916 | 1 | |||
Simultaneous analysis of polyhydroxylated alkaloids by capillary electrophoresis using borate complexation and evaluation of sweeping technique for sensitivity improvement | Chromatographia | 2002 | 614 | 1 | |||
Calystegine distribution in some solanaceous species | Phytochemistry | 2001 | 608 | 0 | |||
Capillary electrophoresis and high-performance anion exchange chromatography for monitoring caseinoglycomacropeptide sialylation | Journal of pharmaceutical and biomedical analysis | 2001 | 516 | 0 | |||
Routine o-glycan characterization in nutritional supplements--a comparison of analytical methods for the monitoring of the bovine kappa-casein macropeptide glycosylation | Journal of chromatography | 2001 | 587 | 0 | |||
Use of borate complexation for the separation of non-UV-absorbing calystegines by capillary electrophoresis | Journal of chromatography | 2000 | 598 | 0 | |||
Partial solubility parameters of lactose, mannitol and saccharose using the modified extended Hansen method and evaporation light scattering detection | Chemical and pharmaceutical bulletin | 2000 | 518 | 0 | |||
Experimental design for enantioselective separation of celiprolol by capillary electrophoresis using sulfated beta-cyclodextrin | Electrophoresis | 1999 | 588 | 2 | |||
Development and validation of liquid chromatography and capillary electrophoresis methods for acarbose determination in pharmaceutical tablets | Journal of pharmaceutical and biomedical analysis | 1998 | 597 | 0 |