UNIGE document Scientific Article
previous document  unige:8421  next document
add to browser collection
Title

Development and validation of liquid chromatography and capillary electrophoresis methods for acarbose determination in pharmaceutical tablets

Authors
Published in Journal of Pharmaceutical and Biomedical Analysis. 1998, vol. 18, no. 4-5, p. 729-35
Abstract Liquid chromatography and capillary zone electrophoresis, respectively coupled to an evaporative light scattering detector and a UV detector have been developed for the analysis of acarbose without any derivatization procedure. The electrophoretic separation of acarbose anomers was achieved through the manipulation of the working temperature. Both methods were validated and showed good validation data in terms of precision, accuracy and linearity. The validated methods were successfully applied to the dosage of acarbose in commercially available Glucobay tablets.
Keywords AcarboseChromatography, Liquid/methodsElectrophoresis, Capillary/methodsHypoglycemic Agents/analysisReproducibility of ResultsTablets/chemistryTemperatureTrisaccharides/analysis
Identifiers
PMID: 9919975
Full text
Article (Published version) (99 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Citation
(ISO format)
CHERKAOUI, Samir et al. Development and validation of liquid chromatography and capillary electrophoresis methods for acarbose determination in pharmaceutical tablets. In: Journal of Pharmaceutical and Biomedical Analysis, 1998, vol. 18, n° 4-5, p. 729-35. https://archive-ouverte.unige.ch/unige:8421

213 hits

0 download

Update

Deposited on : 2010-06-24

Export document
Format :
Citation style :