Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics
Published inCPT: pharmacometrics & systems pharmacology, vol. 11, no. 1, p. 30-43
Publication date2022-01
First online date2021-11-17
Abstract
Keywords
- Cytochrome P-450 CYP2C19 / drug effects
- Cytochrome P-450 CYP2C19 Inhibitors / pharmacology
- Cytochrome P-450 CYP3A / drug effects
- Cytochrome P-450 CYP3A Inhibitors / pharmacology
- Down-Regulation
- Drug Interactions
- Esomeprazole / pharmacology
- Humans
- Inflammation / physiopathology
- Interleukin-6 / blood
- Midazolam / pharmacokinetics
- Omeprazole / pharmacology
Citation (ISO format)
LENOIR, Camille et al. Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics. In: CPT: pharmacometrics & systems pharmacology, 2022, vol. 11, n° 1, p. 30–43. doi: 10.1002/psp4.12730
Main files (1)
Article (Published version)
Secondary files (8)
Identifiers
- PID : unige:161946
- DOI : 10.1002/psp4.12730
- PMID : 34791831
- PMCID : PMC8752107
Journal ISSN2163-8306