UNIGE document Scientific Article
previous document  unige:88690  next document
add to browser collection

Detection of busulfan adducts on proteins

Published in RCM. Rapid communications in mass spectrometry. 2016, vol. 30, no. 23, p. 2517-2528
Abstract Busulfan is a bifunctional alkyl sulfonate antineoplastic drug. This alkylating agent was described as forming covalent adducts on proteins. However, only limited data are available regarding the interaction of busulfan with proteins. Mass spectrometry and bioinformatics were used to identify busulfan adducts on human serum albumin and hemoglobin.
PMID: 27599297
Full text
Article (Accepted version) (1.8 MB) - public document Free access
Research groups Swiss Institute of Bioinformatique
Chimie et protéomique clinique (270)
Groupe Desmeules Jules (pharmacologie/toxicologie) (567)
Oncologie et hématologie pédiatrique (907)
Pharmaco-omiques et médecine de précision (1003)
(ISO format)
ACOSTA MARTIN, Adelina Elena et al. Detection of busulfan adducts on proteins. In: RCM. Rapid communications in mass spectrometry, 2016, vol. 30, n° 23, p. 2517-2528. doi: 10.1002/rcm.7730 https://archive-ouverte.unige.ch/unige:88690

505 hits



Deposited on : 2016-11-04

Export document
Format :
Citation style :