JR
Reny, Jean-Luc
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Improving Understanding of Fexofenadine Pharmacokinetics to Assess Pgp Phenotypic Activity in Older Adult Patients Using Population Pharmacokinetic Modeling | Clinical pharmacokinetics | 2025 | 29 | 24 | |||
Impact de la réorganisation des soins pendant les vagues de COVID-19 sur les patients hospitalisés pour un autre diagnostic que le COVID : étude de cohorte rétrospective monocentrique | 90e Congrès Français de Médecine Interne | 2025 | 19 | 0 | |||
Virtual twin approach using physiologically based pharmacokinetic modelling in hospitalized patients treated with apixaban or rivaroxaban | British journal of clinical pharmacology | 2025 | 26 | 0 | |||
Systemic cytokines related to memory function 6-9 months and 12-15 months after SARS-CoV-2 infection | Scientific reports | 2024 | 25 | 69 | |||
Monitoring low-value care in medical patients from Swiss university hospitals using a Findable, Accessible, Interoperable, Reusable (FAIR) national data stream and patient and public involvement : LUCID study protocol | BMJ open | 2024 | 31 | 22 | |||
Persistence and emergence of new neuropsychological deficits following SARS-CoV-2 infection : A follow-up assessment of the Geneva COVID-COG cohort | Journal of global health | 2024 | 75 | 32 | |||
Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study) | BMJ open | 2024 | 71 | 75 | |||
Frequency of Abnormally Low Neuropsychological Scores in Post-COVID-19 Syndrome: the Geneva COVID-COG Cohort | Archives of clinical neuropsychology | 2023 | 437 | 228 | |||
Brain functional connectivity alterations associated with neuropsychological performance 6–9 months following SARS‐CoV ‐2 infection | Human brain mapping | 2023 | 229 | 50 | |||
Acute TNFα levels predict cognitive impairment 6-9 months after COVID-19 infection | Psychoneuroendocrinology | 2023 | 177 | 67 | |||
Use of complementary medicine and its association with SARS-CoV-2 vaccination during the COVID-19 pandemic : a longitudinal cohort study | Swiss medical weekly | 2023 | 18 | 15 | |||
Markers of limbic system damage following SARS-CoV-2 infection | Brain communications | 2023 | 231 | 57 | |||
Apixaban and rivaroxaban's physiologically-based pharmacokinetic model validation in hospitalized patients: A first step for larger use of a priori modeling approach at bed side | CPT: pharmacometrics & systems pharmacology | 2023 | 131 | 124 | |||
The longitudinal study of subjective wellbeing and absenteeism of healthcare workers considering post-COVID condition and the COVID-19 pandemic toll | Scientific reports | 2023 | 122 | 24 | |||
Trends in management and outcomes of COVID patients admitted to a Swiss tertiary care hospital | Scientific reports | 2023 | 180 | 39 | |||
Enoxaparin versus placebo to prevent symptomatic venous thromboembolism in hospitalized older adult medical patients | NEJM evidence | 2023 | 81 | 0 | |||
Prevalence of Post-COVID Condition 12 Weeks After Omicron Infection Compared With Negative Controls and Association With Vaccination Status | Clinical infectious diseases | 2023 | 145 | 122 | |||
Population pharmacokinetics of apixaban in a real-life hospitalized population from the OptimAT study | CPT: pharmacometrics & systems pharmacology | 2023 | 104 | 87 | |||
PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations | BMJ | 2022 | 10 | 0 | |||
Accuracy of a score predicting the presence of an atypical pathogen in hospitalized patients with moderately severe community-acquired pneumonia | BMC infectious diseases | 2022 | 66 | 70 | |||
A bilateral aseptic pyogenic ventriculitis following a course of pembrolizumab, an anti-PD-1 immune checkpoint inhibitor treatment for metastatic small cell lung cancer | Thérapie | 2022 | 31 | 0 | |||
One-year persistent symptoms and functional impairment in SARS-CoV-2 positive and negative individuals | Journal of internal medicine | 2022 | 242 | 73 | |||
Comparison of prognostic scores for inpatients with COVID-19: a retrospective monocentric cohort study | BMJ open respiratory research | 2022 | 263 | 67 | |||
Avancées récentes en médecine interne | Revue médicale suisse | 2022 | 179 | 66 | |||
Dexamethasone exposure in normal-weight and obese hospitalized COVID-19 patients: An observational exploratory trial | Clinical and translational science | 2022 | 132 | 71 | |||
Eight versus 28-point lung ultrasonography in moderate acute heart failure: a prospective comparative study | Internal and emergency medicine | 2022 | 239 | 126 | |||
Impact of the Genotype and Phenotype of CYP3A and P-gp on the Apixaban and Rivaroxaban Exposure in a Real-World Setting | Journal of personalized medicine | 2022 | 200 | 180 | |||
Therapeutic anticoagulation to prevent thrombosis, coagulopathy, and mortality in severe COVID-19: The Swiss COVID-HEP randomized clinical trial | Research and practice in thrombosis and haemostasis | 2022 | 226 | 222 | |||
Outcomes with revascularization and medical therapy in patients with coronary disease and chronic kidney disease: A meta-analysis | Atherosclerosis | 2022 | 132 | 335 | |||
Population Pharmacokinetic Models for Direct Oral Anticoagulants: A Systematic Review and Clinical Appraisal Using Exposure Simulation | Clinical pharmacology and therapeutics | 2022 | 140 | 130 | |||
Development and assessment of PharmaCheck: an electronic screening tool for the prevention of twenty major adverse drug events | BMC medical informatics and decision making | 2022 | 243 | 151 | |||
Confidence and use of physical examination and point-of-care ultrasonography for detection of abdominal or pleural free fluid. A cross-sectional survey | Internal and emergency medicine | 2022 | 201 | 106 | |||
The pandemic toll and post-acute sequelae of SARS-CoV-2 in healthcare workers at a Swiss University Hospital | Preventive medicine reports | 2022 | 221 | 74 | |||
Risk stratification for hospital-acquired venous thromboembolism in medical patients (RISE): Protocol for a prospective cohort study | PloS one | 2022 | 443 | 187 | |||
Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P-Glycoprotein Activities | Clinical pharmacology & therapeutics | 2022 | 157 | 307 | |||
Kinetics of inflammatory biomarkers to predict one-year mortality in older patients hospitalized for pneumonia: a multivariable analysis | International journal of infectious diseases | 2022 | 188 | 145 | |||
The chronification of post-COVID condition associated with neurocognitive symptoms, functional impairment and increased healthcare utilization | Scientific reports | 2022 | 183 | 49 | |||
Impact of SARS-CoV-2 Infection (COVID-19) on Cytochromes P450 Activity Assessed by the Geneva Cocktail | Clinical pharmacology and therapeutics | 2021 | 184 | 106 | |||
Prognosis of Laboratory-Confirmed Influenza and Respiratory Syncytial Virus in Acute Heart Failure | Journal of clinical medicine | 2021 | 211 | 67 | |||
miR-204-5p and Platelet Function Regulation: Insight into a Mechanism Mediated by CDC42 and GPIIbIIIa | Thrombosis and haemostasis | 2021 | 84 | 51 | |||
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy | Annual Review of Pharmacology and Toxicology | 2021 | 407 | 1 | |||
Drug-drug interactions with direct oral anticoagulants: practical recommendations for clinicians | The American journal of medicine | 2021 | 148 | 0 | |||
Mixing Drugs and Genetics: A Complex Hemorrhagic Cocktail | American Journal of Medicine | 2021 | 264 | 5 | |||
2020 en revue par les internistes hospitaliers | Revue médicale suisse | 2021 | 222 | 156 | |||
Electronic monitoring of potential adverse drug events related to lopinavir/ritonavir and hydroxychloroquine during the first wave of COVID-19 | European journal of hospital pharmacy | 2021 | 200 | 0 | |||
An Ex Vivo and In Silico Study Providing Insights into the Interplay of Circulating miRNAs Level, Platelet Reactivity and Thrombin Generation: Looking beyond Traditional Pharmacogenetics | Journal of Personalized Medicine | 2021 | 224 | 152 | |||
Role of Clinical Characteristics and Biomarkers at Admission to Predict One-Year Mortality in Elderly Patients with Pneumonia | Journal of clinical medicine | 2021 | 244 | 125 | |||
Head-to-head evaluation of five automated SARS-CoV-2 serology immunoassays in various prevalence settings | Journal of Clinical Medicine | 2021 | 317 | 145 | |||
Role of Intermediate Care Unit Admission and Noninvasive Respiratory Support during the COVID-19 Pandemic: A Retrospective Cohort Study | Respiration | 2021 | 208 | 191 | |||
Accuracy of C-reactive protein, procalcitonin, serum amyloid A and neopterin for low-dose CT-scan confirmed pneumonia in elderly patients: A prospective cohort study | PLOS ONE | 2020 | 339 | 174 | |||
Platelet function test use for patients with coronary artery disease in the early 2020s | Journal of clinical medicine | 2020 | 172 | 87 | |||
Early experimental COVID-19 therapies: associations with length of hospital stay, mortality and related costs | Swiss Medical Weekly | 2020 | 475 | 335 | |||
Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium | Clinical Pharmacology and Therapeutics | 2020 | 170 | 74 | |||
Diagnostic accuracy of Augurix COVID-19 IgG serology rapid test | European Journal of Clinical Investigation | 2020 | 425 | 349 | |||
MicroRNA-126 is a regulator of platelet-supported thrombin generation | Platelets | 2020 | 287 | 243 | |||
The well-being of Swiss general internal medicine residents | Swiss Medical Weekly | 2020 | 343 | 222 | |||
Head-to-head accuracy comparison of three commercial COVID-19 IgM/IgG serology rapid tests | Journal of Clinical Medicine | 2020 | 360 | 173 | |||
Point of care ultrasonography from the emergency department to the internal medicine ward: current trends and perspectives | Internal and Emergency Medicine | 2020 | 284 | 1,563 | |||
Guillain-Barré syndrome as a complication of SARS-CoV-2 infection | Brain, behavior, and immunity | 2020 | 234 | 71 | |||
Functional Independence Measure score is associated with mortality in critically ill elderly patients admitted to an intermediate care unit | BMC Geriatrics | 2020 | 204 | 150 | |||
Feasibility and safety of high-intensity interval training for the rehabilitation of geriatric inpatients (HIITERGY) a pilot randomized study | BMC Geriatrics | 2020 | 262 | 152 | |||
Vegetarian, pescatarian and flexitarian diets: sociodemographic determinants and association with cardiovascular risk factors in a Swiss urban population | The British journal of nutrition | 2020 | 195 | 132 | |||
Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients | Journal of Thrombosis and Haemostasis | 2020 | 271 | 1 | |||
Methods to investigate miRNA function: focus on platelet reactivity | Thrombosis and Haemostasis | 2020 | 227 | 72 | |||
A high glucose level is associated with decreased aspirin-mediated acetylation of platelet cyclooxygenase (COX)-1 at serine 529: A pilot study | Journal of Proteomics | 2019 | 508 | 368 | |||
Functional validation of microRNA-126-3p as a platelet reactivity regulator using human haematopoietic stem cells | Thrombosis and Haemostasis | 2019 | 493 | 418 | |||
Associations between early handoffs, length of stay and complications in internal medicine wards: A retrospective study | European journal of internal medicine | 2019 | 147 | 1 | |||
Towards personalized antithrombotic treatments: focus on P2Y12 inhibitors and direct oral anticoagulants | Clinical Pharmacokinetics | 2019 | 472 | 2 | |||
Médecine interne hospitalière en revue | Revue médicale suisse | 2019 | 247 | 128 | |||
Anticoagulant therapy for acute venous thrombo-embolism in cancer patients: A systematic review and network meta-analysis | PLOS ONE | 2019 | 257 | 161 | |||
Platelet Function Testing or Genotyping: Which Should We Trust? | JACC: Cardiovascular Interventions | 2019 | 199 | 0 | |||
Accuracy of comprehensive PCR analysis of nasopharyngeal and oropharyngeal swabs for CT-scan-confirmed pneumonia in elderly patients: a prospective cohort study | Clinical Microbiology and Infection | 2019 | 420 | 143 | |||
Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites | Clinical Pharmacokinetics | 2018 | 682 | 694 | |||
Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives | Clinical Pharmacokinetics | 2018 | 498 | 673 | |||
Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC) | American Heart Journal | 2018 | 470 | 159 | |||
Large bowel obstruction: a case of uncommon aetiology of a frequent condition | Age and Ageing | 2018 | 252 | 0 | |||
Low-dose computed tomography for the diagnosis of pneumonia in elderly patients: a prospective, interventional cohort study | European Respiratory Journal | 2018 | 522 | 104 | |||
Platelet reactivity in stable cardiovascular patients with chronic kidney disease | Platelets | 2018 | 506 | 0 | |||
Functional Performances on Admission Predict In-Hospital Falls, Injurious Falls, and Fractures in Older Patients: A Prospective Study | Journal of Bone and Mineral Research | 2018 | 513 | 3 | |||
Shotgun proteomics data on the impact of hyperglycaemia on platelet protein acetylation by aspirin | Data in Brief | 2018 | 472 | 168 | |||
Diagnosis of systemic lupus erythematosus by presence of Hargraves cells in eosinophilic pleural effusion | Medicine (Baltimore) | 2018 | 230 | 95 | |||
Pannexin1 Single Nucleotide Polymorphism and Platelet Reactivity in a Cohort of Cardiovascular Patients | Cell communication & adhesion | 2017 | 551 | 2 | |||
Acute Appendicitis in Elderly Adults: A Difficult Diagnosis | Journal of the American Geriatrics Society | 2016 | 639 | 0 | |||
Vascular risk levels affect the predictive value of platelet reactivity for the occurrence of MACE in patients on clopidogrel. Systematic review and meta-analysis of individual patient data | Thrombosis and haemostasis | 2016 | 548 | 177 | |||
Genetics of clopidogrel poor-response | Antiplatelet Therapy in Cardiovascular Disease | 2016 | 497 | 0 | |||
New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach | Human genetics | 2016 | 808 | 214 | |||
Sepsis chez le sujet âgé : quelles spécificités ? | Revue médicale suisse | 2016 | 683 | 506 | |||
PPM1A Methylation Is Associated With Vascular Recurrence in Aspirin-Treated Patients | Stroke | 2016 | 534 | 0 | |||
Aspirin response: Differences in serum thromboxane B2 levels between clinical studies | Platelets | 2016 | 692 | 1 | |||
Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach | Clinical pharmacology and therapeutics | 2016 | 635 | 694 | |||
Pharmacogenomics of Oral Antithrombotic Drugs | Current pharmaceutical design | 2016 | 599 | 0 | |||
Simple comme un SMS ! | La Revue de médecine interne | 2016 | 498 | 146 | |||
TRAF3 Epigenetic Regulation Is Associated With Vascular Recurrence in Patients With Ischemic Stroke | Stroke | 2016 | 509 | 0 | |||
An unusual cause of bilateral lower extremity edema in an older woman | Journal of the American Geriatrics Society | 2015 | 553 | 2 | |||
Antiplatelet drugs and platelet reactivity: is it time to halt clinical research on tailored strategies? | Expert opinion on pharmacotherapy | 2015 | 655 | 2 | |||
Treatment of systemic necrotizing vasculitides in patients aged sixty-five years or older: results of a multicenter, open-label, randomized controlled trial of corticosteroid and cyclophosphamide-based induction therapy | Arthritis & rheumatology | 2015 | 578 | 0 | |||
Impact of non-inhibited platelet supplementation on platelet reactivity in patients treated with prasugrel or ticagrelor for an acute coronary syndrome: An ex vivo study | Platelets | 2015 | 566 | 0 | |||
Mon patient est trop âgé pour une statine : mythes et réalités | Revue médicale suisse | 2015 | 452 | 0 | |||
Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis | European journal of vascular and endovascular surgery | 2015 | 564 | 233 | |||
Suspicion of heparin-induced thrombocytopenia in internal medicine: How appropriate is the ordering of anti-PF4/heparin antibody testing? | Platelets | 2015 | 662 | 3 | |||
A Case of Tuberculous Granulomatous Panniculitis without Vasculitis | Case reports in dermatology | 2015 | 616 | 261 | |||
Pneumonie chez le sujet âgé : y a-t-il des spécificités ? | Revue médicale suisse | 2014 | 588 | 2 | |||
Hémostase. Aspirine: une ou deux fois par jour? | Revue médicale suisse | 2014 | 560 | 0 | |||
How to manage prasugrel and ticagrelor in daily practice | European journal of internal medicine | 2014 | 477 | 488 | |||
Antiplatelet Therapy: Targeting the TxA2 Pathway | Journal of cardiovascular translational research | 2014 | 625 | 2 | |||
Role of paraoxonase-1 in CYP2C19 loss-of-function carriers | Thrombosis research | 2014 | 653 | 0 | |||
Characterization of the platelet granule proteome: Evidence of the presence of MHC1 in alpha-granules | Journal of proteomics | 2014 | 776 | 3 | |||
Tailored Thienopyridine therapy: no urgency for CYP2C19 genotyping | Journal of the American Heart Association. Cardiovascular and cerebrovascular disease | 2013 | 570 | 0 | |||
Antiplaquettaires et patients âgés : quelles molécules et quelles preuves ? | Revue médicale suisse | 2013 | 554 | 0 | |||
Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding | Journal of the American College of Cardiology | 2013 | 488 | 777 | |||
Unraveling modulators of platelet reactivity incardiovascular patients using omics strategies: Towards anetwork biology paradigm | Translational proteomics | 2013 | 629 | 537 | |||
Antiplatelet drug response status does not predict recurrent ischemic events in stable cardiovascular patients: results of the Antiplatelet Drug Resistances and Ischemic Events study | Circulation | 2012 | 717 | 29 | |||
Intramural hematoma of the esophagus | Case reports in gastroenterology | 2012 | 525 | 0 | |||
Application pratique et intérêt des recommandations de prise en charge des syncopes : évaluation de pratiques professionnelles | Annales de cardiologie et d'angéiologie | 2012 | 548 | 0 | |||
Prevalence of poor biological response to clopidogrel: a systematic review | Thrombosis and haemostasis | 2012 | 522 | 0 | |||
Poor responsiveness to antiplatelet drugs in acute coronary syndromes: clinical relevance and management | Cardiovascular therapeutics | 2012 | 612 | 0 | |||
Nutrition entérale : sonde nasogastrique ou gastrostomie percutanée endoscopique? | Revue médicale suisse | 2012 | 617 | 2 | |||
Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis | Journal of thrombosis and haemostasis | 2012 | 601 | 0 | |||
Severe mitral valve regurgitation in polymyositis | Journal of clinical rheumatology | 2012 | 543 | 0 | |||
The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro | British journal of pharmacology | 2012 | 554 | 0 | |||
Thrombose coronaire distale compliquant une leucémie aiguë lymphoblastique traitée par asparaginase | Annales de cardiologie et d'angéiologie | 2012 | 664 | 515 | |||
Platelet proteomics | Mass spectrometry reviews | 2012 | 522 | 2 | |||
Relationship between paraoxonase-1 activity, its Q192R genetic variant and clopidogrel responsiveness in the ADRIE study | Journal of thrombosis and haemostasis | 2011 | 620 | 0 | |||
Une histoire pas très originale dans un contexte pas très confortable...Hemoptysis in a 55-year-old man | La Revue de médecine interne | 2011 | 615 | 0 | |||
Platelet reactivity is a stable and global phenomenon in aspirin-treated cardiovascular patients | Thrombosis and haemostasis | 2011 | 631 | 0 | |||
Anémie ferriprive, inflammatoire ou mixte: comment orienter le diagnostic? | Revue médicale suisse | 2011 | 1,261 | 5 | |||
Médecine interne hospitalière : l'année 2010 en revue (1) | Revue médicale suisse | 2011 | 956 | 0 | |||
Clinical implications of clopidogrel non-response in cardiovascular patients: a systematic review and meta-analysis | Journal of thrombosis and haemostasis | 2010 | 545 | 0 | |||
Maladies cardiovasculaires, antiagrégants, anticoagulants et risque hémorragique | Revue médicale suisse | 2010 | 593 | 0 | |||
Médecine interne hospitalière : l'année 2009 en revue (2) | Revue médicale suisse | 2010 | 571 | 1 | |||
Evaluation de l'efficacité biologique du clopidogrel: génotype ou phénotype? | Revue médicale suisse | 2010 | 505 | 0 | |||
Antiagregants plaquettaires : lequel, quand et pour qui ? | La Revue de médecine interne | 2010 | 494 | 0 | |||
Clinical predictors of dual aspirin and clopidogrel poor responsiveness in stable cardiovascular patients from the ADRIE study | Journal of thrombosis and haemostasis | 2010 | 578 | 0 | |||
Acute coronary syndrome and its antithrombotic treatment: focus on aspirin and clopidogrel resistance | Current vascular pharmacology | 2009 | 505 | 0 | |||
Le concept de "resistance" a l'aspirine: mecanismes et pertinence clinique | La Revue de médecine interne | 2009 | 541 | 0 | |||
Platelet hyperreactivity and dual antiplatelet therapy: can biases be avoided? | Journal of thrombosis and haemostasis | 2009 | 502 | 0 | |||
Use of the PFA-100 closure time to predict cardiovascular events in aspirin-treated cardiovascular patients: a systematic review and meta-analysis | Journal of thrombosis and haemostasis | 2008 | 640 | 0 | |||
Laboratory-defined aspirin resistance and recurrent cardiovascular events | Archives of internal medicine | 2008 | 559 | 0 | |||
Aspirin "resistance" and risk of cardiovascular morbidity | BMJ. British medical journal | 2008 | 515 | 1 | |||
Aspirin response variability assessed with the PFA-100 device | Thrombosis and haemostasis | 2008 | 590 | 0 | |||
Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects | Circulation | 2003 | 268 | 98 |