Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium
ContributorsVerma, Shefali Setia; Bergmeijer, Thomas O; Gong, Li; Reny, Jean-Luc
; Lewis, Joshua P; Mitchell, Braxton D; Alexopoulos, Dimitrios; Aradi, Daniel; Altman, Russ B; Bliden, Kevin; Bradford, Yuki; Campo, Gianluca; Chang, Kiyuk; Cleator, John H; Déry, Jean-Pierre; Dridi, Nadia P; Fernandez-Cadenas, Israel; Fontana, Pierre; Gawaz, Meinrad; Geisler, Tobias; Gensini, Gian Franco; Giusti, Betti; Gurbel, Paul A; Hochholzer, Willibald; Holmvang, Lene; Kim, Eun-Young; Kim, Ho-Sook; Marcucci, Rossella; Montaner, Joan; Backman, Joshua D; Pakyz, Ruth E; Roden, Dan M; Schaeffeler, Elke; Schwab, Matthias; Shin, Jae Gook; Siller-Matula, Jolanta M; Ten Berg, Jurriën M; Trenk, Dietmar; Valgimigli, Marco; Wallace, John; Wen, Ming-Shien; Kubo, Michiaki; Lee, Ming Ta Michael; Whaley, Ryan; Winter, Stefan; Klein, Teri E; Shuldiner, Alan R; Ritchie, Marylyn D; ICPC Investigators

Published inClinical Pharmacology and Therapeutics, vol. 108, no. 5, p. 1067-1077
Publication date2020
Abstract
Keywords
- Aged
- Blood Platelets/drug effects/metabolism
- Cardiovascular Diseases/blood/genetics/mortality/prevention & control
- Clopidogrel/adverse effects/therapeutic use
- Coronary Artery Disease/mortality/therapy
- Cytochrome P-450 CYP2C19/genetics/metabolism
- Female
- Genome-Wide Association Study
- Humans
- Male
- Middle Aged
- Percutaneous Coronary Intervention/adverse effects/mortality
- Pharmacogenetics
- Pharmacogenomic Variants
- Platelet Aggregation Inhibitors/adverse effects/therapeutic use
- Polymorphism, Single Nucleotide
- Risk Assessment
- Risk Factors
- Treatment Outcome
Research group
Citation (ISO format)
VERMA, Shefali Setia et al. Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium. In: Clinical Pharmacology and Therapeutics, 2020, vol. 108, n° 5, p. 1067–1077. doi: 10.1002/cpt.1911
Main files (1)
Article (Published version)
Identifiers
- PID : unige:155381
- DOI : 10.1002/cpt.1911
- PMID : 32472697
ISSN of the journal0009-9236