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Scientific article
English

TRAF3 Epigenetic Regulation Is Associated With Vascular Recurrence in Patients With Ischemic Stroke

Published inStroke, vol. 47, no. 5, p. 1180-1186
Publication date2016
Abstract

Clopidogrel is one of the most used antiplatelet drugs in patients with cardiovascular disease. However, 16% to 50% of patients have a high on-clopidogrel platelet reactivity and an increased risk of ischemic events. The pathogenesis of high on-treatment platelet reactivity in patients with stroke is only partially explained by genetic variations. This study aims to find differentially methylated sites across the genome associated with vascular recurrence in ischemic stroke patients treated with clopidogrel.

Keywords
  • Aspirin
  • Clopidogrel
  • Methylation
  • Stroke
  • Vascular resistance
Citation (ISO format)
GALLEGO-FABREGA, Cristina et al. TRAF3 Epigenetic Regulation Is Associated With Vascular Recurrence in Patients With Ischemic Stroke. In: Stroke, 2016, vol. 47, n° 5, p. 1180–1186. doi: 10.1161/STROKEAHA.115.012237
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Article (Published version)
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Identifiers
ISSN of the journal0039-2499
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Technical informations

Creation05/18/2016 10:45:00 AM
First validation05/18/2016 10:45:00 AM
Update time03/15/2023 12:27:29 AM
Status update03/15/2023 12:27:28 AM
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