UNIGE document Scientific Article
previous document  unige:79658  next document
add to browser collection

A Case of Tuberculous Granulomatous Panniculitis without Vasculitis

Tehrany, Yassaman Alipour
Published in Case reports in dermatology. 2015, vol. 7, no. 2, p. 141-145
Abstract We report a case of tuberculous granulomatous panniculitis without vasculitis in an 87-year-old female patient with B-cell chronic lymphocytic leukaemia. One month after starting chemotherapy with chlorambucil and prednisone she presented superficial erythematous plaques on the anterior side of the left leg. Three weeks later erythematous painless deep nodules appeared on the left popliteal fossa and on the left thigh. Cutaneous biopsy revealed granulomatous panniculitis without caseation necrosis or vasculitis. Polymerase chain reaction for Mycobacterium tuberculosis revealed positivity in the skin. The final diagnosis was reactivation of latent tuberculosis (TB) induced by deep immunosuppression associated with chemotherapy and haematological disease. Tuberculous granulomatous panniculitis without vasculitis is a rare presentation of cutaneous TB and may be part of the heterogeneous histopathologic spectrum of erythema induratum of Bazin (nodular vasculitis). Our case shows that the diagnosis of cutaneous TB requires the correlation of clinical findings with histopathology and microbiological tests.
PMID: 26351420
Full text
Article (Published version) (803 Kb) - public document Free access
Research group Geneva Platelet Group (13)
(ISO format)
TEHRANY, Yassaman Alipour et al. A Case of Tuberculous Granulomatous Panniculitis without Vasculitis. In: Case reports in dermatology, 2015 , vol. 7, n° 2, p. 141-145. doi: 10.1159/000435831 https://archive-ouverte.unige.ch/unige:79658

490 hits



Deposited on : 2016-01-20

Export document
Format :
Citation style :