Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis

Vazquez, F; Rodger, M; Carrier, M; Le Gal, G; Reny, Jean-Luc; Sofi, F; Mueller, T; Nagpal, S; Jetty, P; Gandara, E

doi:10.1016/j.ejvs.2015.04.033

Scientific article

English

Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis

ContributorsVazquez, F; Rodger, M; Carrier, M; Le Gal, G; Reny, Jean-Luc

; Sofi, F; Mueller, T; Nagpal, S; Jetty, P; Gandara, E

Published inEuropean journal of vascular and endovascular surgery, vol. 50, no. 2, p. 232-240

Publication date2015

Abstract

Despite being an important risk factor for venous thromboembolism, the role of the prothrombin G20210A mutation in patients with arterial disease remains unclear. The aim of this review was to evaluate the association of prothrombin G20210A and lower extremity peripheral arterial disease (PAD).

Keywords

Chi-Square Distribution
Critical Illness
Gene Frequency
Genetic Predisposition to Disease
Humans
Ischemia/diagnosis/genetics
Lower Extremity/blood supply
Mutation
Odds Ratio
Peripheral Arterial Disease/diagnosis/genetics
Phenotype
Prothrombin/genetics
Risk Assessment
Risk Factors
Thrombophilia/blood/complications/diagnosis/genetics

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

Research groups

Plaquettes et antithrombotiques (13)

Citation (ISO format)

VAZQUEZ, F et al. Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis. In: European journal of vascular and endovascular surgery, 2015, vol. 50, n° 2, p. 232–240. doi: 10.1016/j.ejvs.2015.04.033

Article (Published version)

Identifiers

PID : unige:79657
DOI : 10.1016/j.ejvs.2015.04.033
PMID : 26092622

Journal ISSN1078-5884

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Creation11/17/2015 3:09:00 PM

First validation11/17/2015 3:09:00 PM

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Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis

Despite being an important risk factor for venous thromboembolism, the role of the prothrombin G20210A mutation in patients with arterial disease remains unclear. The aim of this review was to evaluate the association of prothrombin G20210A and lower extremity peripheral arterial disease (PAD).

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