Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis

Vazquez, F; Rodger, M; Carrier, M; Le Gal, G; Reny, Jean-Luc; Sofi, F; Mueller, T; Nagpal, S; Jetty, P; Gandara, E

doi:10.1016/j.ejvs.2015.04.033

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Title		Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis
Authors		Vazquez, F Rodger, M Carrier, M Le Gal, G Reny, Jean-Luc Sofi, F Mueller, T Nagpal, S Jetty, P Gandara, E show all authors [1 - 10]
Published in		European Journal of Vascular and Endovascular Surgery. 2015, vol. 50, no. 2, p. 232-240
Abstract		Despite being an important risk factor for venous thromboembolism, the role of the prothrombin G20210A mutation in patients with arterial disease remains unclear. The aim of this review was to evaluate the association of prothrombin G20210A and lower extremity peripheral arterial disease (PAD).
Keywords		Chi-Square Distribution — Critical Illness — Gene Frequency — Genetic Predisposition to Disease — Humans — Ischemia/diagnosis/genetics — Lower Extremity/blood supply — Mutation — Odds Ratio — Peripheral Arterial Disease/diagnosis/genetics — Phenotype — Prothrombin/genetics — Risk Assessment — Risk Factors — Thrombophilia/blood/complications/diagnosis/genetics
Identifiers		DOI: 10.1016/j.ejvs.2015.04.033 PMID: 26092622
Full text		Article (Published version) (987 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie
Research group		Geneva Platelet Group (13)
Citation (ISO format)		VAZQUEZ, F et al. Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review and meta-analysis. In: European Journal of Vascular and Endovascular Surgery, 2015, vol. 50, n° 2, p. 232-240. doi: 10.1016/j.ejvs.2015.04.033 https://archive-ouverte.unige.ch/unige:79657