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Mon patient est trop âgé pour une statine : mythes et réalités

Tahar Chaouche, A
Published in Revue médicale suisse. 2015, vol. 11, no. 494, p. 2110-4
Abstract Lipid-lowering treatment in the elderly patient is conditioned by a high incidence and prevalence of cardiovascular disease in the setting of a limited remaining life span. The clinical benefit of statin therapy can be seen after a few months, thus supporting use in secondary prevention even when the lifespan is restricted to a few years. Recent guidelines propose the use of moderate doses in the elderly > 75 years. The evidence for treatment in primary prevention is weaker and the evaluation of the total cardiovascular risk is complicated by the high baseline risk of many elderly. Rational treatment decisions should be based on biologic rather than chronologic age. Statins are generally well tolerated in the elderly, requiring clinical monitoring only, with particular attention to pharmacokinetic interactions and renal failure.
Keywords Age FactorsAgedAged, 80 and overAlgorithmsHumansHydroxymethylglutaryl-CoA Reductase Inhibitors/contraindicationsHypolipidemic Agents/contraindications
PMID: 26727731
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Research group Geneva Platelet Group (13)
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STEENPASS, Veronika et al. Mon patient est trop âgé pour une statine : mythes et réalités. In: Revue médicale suisse, 2015, vol. 11, n° 494, p. 2110-4. https://archive-ouverte.unige.ch/unige:89957

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Deposited on : 2016-12-07

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