Anticoagulant therapy for acute venous thrombo-embolism in cancer patients: A systematic review and network meta-analysis

Rossel, Anne; Robert-Ebadi, Helia; Combescure, Christophe; Grosgurin, Olivier; Stirnemann, Jérôme; Addeo, Alfredo; Garin, Nicolas; Agoritsas, Thomas; Reny, Jean-Luc; Marti, Christophe

doi:10.1371/journal.pone.0213940

Scientific article

Meta-analysis

English

Anticoagulant therapy for acute venous thrombo-embolism in cancer patients: A systematic review and network meta-analysis

ContributorsRossel, Anne; Robert-Ebadi, Helia; Combescure, Christophe

; Grosgurin, Olivier; Stirnemann, Jérôme; Addeo, Alfredo; Garin, Nicolas; Agoritsas, Thomas

; Reny, Jean-Luc

; Marti, Christophe

Published inPLOS ONE, vol. 14, no. 3, e0213940

Publication date2019

Abstract

Low-molecular-weight heparin (LMWH) is usually recommended for the treatment of cancer-associated thrombosis (CAT) but this treatment requires burdensome daily injections. We did a systematic review to compare the efficacy and safety of direct oral anticoagulants (DOAC), vitamin K antagonists (VKA) and LMWH in patients with CAT.

Keywords

Acute Disease
Administration
Oral
Anticoagulants/administration & dosage/adverse effects/therapeutic use
Factor Xa Inhibitors/administration & dosage/adverse effects/therapeutic use
Female
Hemorrhage/etiology
Heparin
Low-Molecular-Weight/administration & dosage/adverse effects/therapeutic use
Humans
Male
Neoplasms/complications
Network Meta-Analysis
Recurrence
Risk Factors
Safety
Secondary Prevention
Venous Thromboembolism/drug therapy/etiology/prevention & control
Vitamin K/antagonists & inhibitors

Affiliation entities

Research groups

Citation (ISO format)

ROSSEL, Anne et al. Anticoagulant therapy for acute venous thrombo-embolism in cancer patients: A systematic review and network meta-analysis. In: PLOS ONE, 2019, vol. 14, n° 3, p. e0213940. doi: 10.1371/journal.pone.0213940

Article (Published version)

CC BY

Identifiers

PID : unige:145169
DOI : 10.1371/journal.pone.0213940
PMID : 30897142

Additional URL for this publicationhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428324/

Journal ISSN1932-6203

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Anticoagulant therapy for acute venous thrombo-embolism in cancer patients: A systematic review and network meta-analysis

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