ND
Demaurex, Nicolas
Affiliation entities
Research groups
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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S-acylation of Ca2+ transport proteins : molecular basis and functional consequences | Biochemical Society transactions | 2024 | 34 | 11 | |||
Deciphering calcium signals in cells and tissues with tailored probes and models | Journal of physiology | 2023 | 60 | 0 | |||
Discovery and validation of new Hv1 proton channel inhibitors with onco-therapeutic potential | Biochimica et biophysica acta. Molecular cell research | 2023 | 163 | 62 | |||
Calcium storage in multivesicular endo-lysosome | Physical biology | 2023 | 76 | 35 | |||
Extending the contacts breaks the flow | Contact | 2023 | 29 | 8 | |||
The lipid transfer proteins Nir2 and Nir3 sustain phosphoinositide signaling and actin dynamics during phagocytosis | Journal of cell science | 2023 | 52 | 22 | |||
The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation | Cell reports | 2023 | 52 | 29 | |||
SARS-CoV-2 infection alkalinizes the ERGIC and lysosomes through the viroporin activity of the viral envelope protein | Journal of cell science | 2023 | 95 | 362 | |||
Enforced tethering elongates the cortical endoplasmic reticulum and limits store-operated calcium entry | Journal of cell science | 2022 | 237 | 65 | |||
TMBIM5 is the Ca 2+ /H + antiporter of mammalian mitochondria | EMBO reports | 2022 | 86 | 104 | |||
The TAM-associated STIM1I484R mutation increases ORAI1 channel function due to a reduced STIM1 inactivation break and an absence of microtubule trapping | Cell calcium | 2022 | 166 | 77 | |||
The mammalian trafficking chaperone protein UNC93B1 maintains the ER calcium sensor STIM1 in a dimeric state primed for translocation to the ER cortex | The Journal of biological chemistry | 2022 | 117 | 87 | |||
S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by Jurkat T cell receptors at the immune synapse | eLife | 2021 | 143 | 89 | |||
Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1 | Science advances | 2021 | 148 | 72 | |||
Proteins Interacting with STIM1 and Store-Operated Ca2+ Entry | Cellular biology of the endoplasmic reticulum | 2021 | 152 | 0 | |||
Simultaneous determination of intraluminal lysosomal calcium and pH by dextran-conjugated fluorescent dyes | Methods in Cell Biology | 2021 | 310 | 7 | |||
Molecular mechanisms of calcium signaling during phagocytosis | Molecular and cellular biology of phagocytosis | 2020 | 291 | 6 | |||
RB501, RB502, RB503, RB504 and RB505 antibodies recognize the human UNC93B1 protein by ELISA | Antibody Reports | 2019 | 262 | 64 | |||
Signaling and functional competency of neutrophils derived from bone-marrow cells expressing the ER-HOXB8 oncoprotein | Journal of leukocyte biology | 2019 | 72 | 70 | |||
ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain | The Journal of Physiology | 2018 | 405 | 206 | |||
GRAM marks the spot for STIM. Commentary on "GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells" | Cell Calcium | 2018 | 333 | 222 | |||
The role of STIM proteins in neutrophil functions | The Journal of Physiology | 2018 | 324 | 196 | |||
The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification | Cell Host & Microbe | 2018 | 472 | 274 | |||
Ultrastructural Characterization of Flashing Mitochondria | Contact (Thousand Oaks) | 2018 | 387 | 201 | |||
The ER phagosome connection in the era of membrane contact sites | Biochimica et Biophysica Acta | 2017 | 469 | 4 | |||
STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells | Nature Communications | 2017 | 535 | 290 | |||
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells | Nature Communications | 2017 | 445 | 202 | |||
Illuminating redox biology using NADH- and NADPH-specific sensors | Nature Methods | 2017 | 385 | 1 | |||
The Role of Mitochondria in the Activation/Maintenance of SOCE: Membrane Contact Sites as Signaling Hubs Sustaining Store-Operated Ca2+ Entry | Advances in Experimental Medicine and Biology | 2017 | 440 | 1 | |||
L-OPA1 regulates mitoflash biogenesis independently from membrane fusion | EMBO Reports | 2017 | 466 | 211 | |||
MitoNEET-dependent formation of intermitochondrial junctions | Proceedings of the National Academy of Sciences | 2017 | 503 | 172 | |||
Redox Control of Mitochondrial Calcium Uptake | Molecular Cell | 2017 | 434 | 2 | |||
ORAI1 Mutations with Distinct Channel Gating Defects in Tubular Aggregate Myopathy | Human mutation | 2017 | 463 | 507 | |||
Mitochondrial Flashes: Dump Superoxide and Dance with Protons Now | Antioxidants & redox signaling | 2016 | 369 | 298 | |||
The antidepressant fluoxetine induces necrosis by energy depletion and mitochondrial calcium overload | Oncotarget | 2016 | 462 | 0 | |||
Neutrophils: Their Role in Innate and Adaptive Immunity | Journal of immunology research | 2016 | 475 | 256 | |||
The role of STIM and ORAI proteins in phagocytic immune cells | The American journal of physiology | 2016 | 538 | 5 | |||
Redox modulation of STIM-ORAI signaling | Cell calcium | 2016 | 525 | 273 | |||
Measuring Phagosome pH by Ratiometric Fluorescence Microscopy | Journal of visualized experiments | 2015 | 454 | 2 | |||
Junctate boosts phagocytosis by recruiting endoplasmic reticulum Ca2+ stores near phagosomes | Journal of cell science | 2015 | 549 | 252 | |||
STIM1L traps and gates Orai1 channels without remodeling the cortical ER | Journal of cell science | 2015 | 685 | 1 106 | |||
Voltage-Gated Proton Channels as Novel Drug Targets: From NADPH Oxidase Regulation to Sperm Biology | Antioxidants & redox signaling | 2015 | 640 | 0 | |||
The 'mitoflash' probe cpYFP does not respond to superoxide | Nature | 2014 | 542 | 1 | |||
Hv1 proton channels differentially regulate the pH of neutrophil and macrophage phagosomes by sustaining the production of phagosomal ROS that inhibit the delivery of vacuolar ATPases | Journal of leukocyte biology | 2014 | 665 | 3 | |||
NCLX Protein, but Not LETM1, Mediates Mitochondrial Ca2+ Extrusion, Thereby Limiting Ca2+-induced NAD(P)H Production and Modulating Matrix Redox State | The Journal of biological chemistry | 2014 | 615 | 361 | |||
Redox regulation of Store Operated Ca2+ Entry | Antioxidants & redox signaling | 2014 | 599 | 595 | |||
Regulation Of The NADPH Oxidase And Associated Ion Fluxes During Phagocytosis | Traffic | 2013 | 626 | 2 | |||
Mitochondrial Ca2+ uptake from plasma membrane cav3.2 protein channels contributes to ischemic toxicity in PC12 cells | The Journal of biological chemistry | 2013 | 626 | 287 | |||
OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange | EMBO journal | 2013 | 665 | 621 | |||
Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 546 | 2 | |||
Do Hv1 proton channels regulate the ionic and redox homeostasis of phagosomes? | Molecular and cellular endocrinology | 2012 | 621 | 544 | |||
STIM1 Juxtaposes ER to Phagosomes, Generating Ca(2+) Hotspots that Boost Phagocytosis | Current biology | 2012 | 630 | 5 | |||
Regulation of the mitochondrial proton gradient by cytosolic Ca(2+) signals | Pflügers Archiv | 2012 | 627 | 400 | |||
Morphological and functional aspects of STIM1-dependent assembly and disassembly of store-operated calcium entry complexes | Biochemical Society transactions | 2012 | 615 | 0 | |||
Perspectives on: SGP Symposium on Mitochondrial Physiology and Medicine: The renaissance of mitochondrial pH | Journal of General Physiology (0022-1295) | 2012 | 566 | 0 | |||
The potential role of cobalt ions released from metal prosthesis on the inhibition of Hv1 proton channels and the decrease in Staphyloccocus epidermidis killing by human neutrophils | Biomaterials | 2011 | 642 | 6 | |||
Securin and separase modulate membrane traffic by affecting endosomal acidification | Traffic | 2011 | 633 | 420 | |||
Local cytosolic Ca2+ elevations are required for stromal interaction molecule 1 (STIM1) de-oligomerization and termination of store-operated Ca2+ entry | The Journal of biological chemistry | 2011 | 638 | 283 | |||
Remodelling of the endoplasmic reticulum during store-operated calcium entry | Biology of the cell | 2011 | 634 | 0 | |||
Uncoupling protein 3 (UCP3) modulates the activity of Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) by decreasing mitochondrial ATP production | The Journal of biological chemistry | 2011 | 561 | 321 | |||
Dynamic regulation of the mitochondrial proton gradient during cytosolic calcium elevations | The Journal of biological chemistry | 2011 | 652 | 406 | |||
Mitochondrial calcium handling during ischemia-induced cell death in neurons | Biochimie | 2011 | 647 | 583 | |||
Glutamate transport decreases mitochondrial pH and modulates oxidative metabolism in astrocytes | The Journal of neuroscience | 2011 | 556 | 600 | |||
SLP-2 negatively modulates mitochondrial sodium-calcium exchange | Cell calcium | 2010 | 633 | 608 | |||
Physiological roles of voltage-gated proton channels in leukocytes | Journal of physiology | 2010 | 557 | 0 | |||
VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification | The Journal of experimental medicine | 2010 | 566 | 1 | |||
The role of calcium signaling in phagocytosis | Journal of leukocyte biology | 2010 | 579 | 3 | |||
Calcium uptake mechanisms of mitochondria | Biochimica et biophysica acta | 2010 | 442 | 0 | |||
STIM1- and Orai1-dependent store-operated calcium entry regulates human myoblast differentiation | The Journal of biological chemistry | 2009 | 672 | 0 | |||
Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells | British journal of pharmacology | 2009 | 575 | 0 | |||
Regulation of plasma membrane calcium fluxes by mitochondria | Biochimica et biophysica acta | 2009 | 600 | 2 | |||
Reactive oxygen species are NOXious for neurons | Nature neuroscience | 2009 | 552 | 3 | |||
Cell biology. A revolving door for calcium | Science | 2009 | 497 | 0 | |||
Mitochondrial regulation of sarcoplasmic reticulum Ca2+ content in vascular smooth muscle cells | Circulation research | 2009 | 553 | 0 | |||
Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic beta-cell activation | EMBO journal | 2009 | 515 | 0 | |||
From the Cover: STIM1-induced precortical and cortical subdomains of the endoplasmic reticulum | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 487 | 0 | |||
Local and global calcium signals associated with the opening of neuronal alpha7 nicotinic acetylcholine receptors | Cell calcium | 2009 | 490 | 0 | |||
Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store-overload-induced Ca2+ release | Biochemical journal | 2008 | 555 | 0 | |||
Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2+ store depletion in endothelial cells | Cell calcium | 2008 | 551 | 2 | |||
Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells | The Journal of biological chemistry | 2008 | 602 | 0 | |||
Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion | Endocrinology | 2008 | 587 | 0 | |||
STIM1 knockdown reveals that store-operated Ca2+ channels located close to sarco/endoplasmic Ca2+ ATPases (SERCA) pumps silently refill the endoplasmic reticulum | The Journal of biological chemistry | 2007 | 538 | 67 | |||
NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation | Biochimie | 2007 | 628 | 0 | |||
Role of nucleotides and phosphoinositides in the stability of electron and proton currents associated with the phagocytic NADPH oxidase | Biochemical journal | 2006 | 636 | 280 | |||
GABA regulates dendritic growth by stabilizing lamellipodia in newly generated interneurons of the olfactory bulb | The Journal of neuroscience | 2006 | 574 | 0 | |||
Gelsolin mediates calcium-dependent disassembly of Listeria actin tails | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 500 | 0 | |||
Electron and proton transport by NADPH oxidases | Philosophical transactions - Royal Society. Biological sciences | 2005 | 622 | 257 | |||
Voltage- and NADPH-dependence of electron currents generated by the phagocytic NADPH oxidase | Biochemical journal | 2005 | 555 | 0 | |||
HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse | Traffic | 2005 | 673 | 0 | |||
Endosome-to-cytosol transport of viral nucleocapsids | Nature cell biology | 2005 | 536 | 0 | |||
Subplasmalemmal mitochondria modulate the activity of plasma membrane Ca2+-ATPases | The Journal of biological chemistry | 2005 | 572 | 327 | |||
Calcium measurements in organelles with Ca2+-sensitive fluorescent proteins | Cell calcium | 2005 | 609 | 761 | |||
Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1 | The Journal of biological chemistry | 2004 | 594 | 378 | |||
ARF1 regulates Nef-induced CD4 degradation | Current biology | 2004 | 651 | 0 | |||
Intracellular transport of calcium from plasma membrane to mitochondria in adrenal H295R cells: implication for steroidogenesis | Endocrinology | 2003 | 634 | 327 | |||
Interactions between electron and proton currents in excised patches from human eosinophils | The Journal of general physiology | 2003 | 443 | 337 | |||
Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, sore-operated Ca2+ entry, and Ca2+ store refilling | The Journal of biological chemistry | 2003 | 580 | 262 | |||
Measurements of the free luminal ER Ca(2+) concentration with targeted "cameleon" fluorescent proteins | Cell calcium | 2003 | 651 | 716 | |||
A tyrosine-based sorting signal is involved in connexin43 stability and gap junction turnover | Journal of cell science | 2003 | 557 | 292 | |||
Cell biology. Apoptosis--the calcium connection | Science | 2003 | 1 053 | 775 | |||
pH Homeostasis of cellular organelles | News in physiological sciences | 2002 | 565 | 1 425 | |||
NOX family NADPH oxidases: do they have built-in proton channels? | The Journal of general physiology | 2002 | 421 | 0 | |||
The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells | The Journal of immunology | 2002 | 633 | 0 | |||
Calreticulin differentially modulates calcium uptake and release in the endoplasmic reticulum and mitochondria | The Journal of biological chemistry | 2002 | 626 | 346 | |||
Molecular and functional characterization of a new X-linked chronic granulomatous disease variant (X91+) case with a double missense mutation in the cytosolic gp91phox C-terminal tail | Biochimica et biophysica acta | 2002 | 634 | 1 005 | |||
Measurement of intracellular Ca2+ concentration | Methods in cell biology | 2002 | 542 | 1 | |||
Subplasmalemmal endoplasmic reticulum controls K(Ca) channel activity upon stimulation with a moderate histamine concentration in a human umbilical vein endothelial cell line | Journal of physiology | 2002 | 635 | 367 | |||
Spontaneous calcium oscillations control c-fos transcription via the serum response element in neuroendocrine cells | The Journal of biological chemistry | 2002 | 503 | 519 | |||
Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions | The Journal of biological chemistry | 2001 | 580 | 0 | |||
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes | The Journal of biological chemistry | 2001 | 582 | 0 | |||
Angiotensin II promotes selective uptake of high density lipoprotein cholesterol esters in bovine adrenal glomerulosa and human adrenocortical carcinoma cells through induction of scavenger receptor class B type I | Endocrinology | 2001 | 630 | 368 | |||
Functional specialization of calreticulin domains | The Journal of cell biology | 2001 | 553 | 0 | |||
Heme histidine ligands within gp91(phox) modulate proton conduction by the phagocyte NADPH oxidase | The Journal of biological chemistry | 2001 | 565 | 0 | |||
The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components | Molecular biology of the cell | 2000 | 630 | 590 | |||
Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 501 | 0 | |||
HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes | Nature cell biology | 2000 | 613 | 1 | |||
A mammalian H+ channel generated through alternative splicing of the NADPH oxidase homolog NOH-1 | Science | 2000 | 603 | 0 | |||
Alternative mechanisms of vacuolar acidification in H(+)-ATPase-deficient yeast | The Journal of biological chemistry | 1999 | 532 | 288 | |||
Angiotensin II negatively modulates L-type calcium channels through a pertussis toxin-sensitive G protein in adrenal glomerulosa cells | The Journal of biological chemistry | 1999 | 678 | 304 | |||
A novel H(+) conductance in eosinophils: unique characteristics and absence in chronic granulomatous disease | The Journal of experimental medicine | 1999 | 493 | 0 | |||
Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes | Cell | 1999 | 590 | 211 | |||
Electron currents generated by the human phagocyte NADPH oxidase | Nature | 1998 | 491 | 0 | |||
Highly cooperative Ca2+ elevations in response to Ins(1,4,5)P3 microperfusion through a patch-clamp pipette | Biophysical journal | 1995 | 561 | 0 | |||
Caracterisation de l'influx Ca2+ dans les neutrophiles humains par la technique du patch clamp | Schweizerische medizinische Wochenschrift | 1995 | 528 | 0 | |||
Combination of microfluorimetric monitoring of cytosolic calcium and pH with patch clamp electrophysiological recordings in neutrophil granulocytes | Methods in enzymology | 1994 | 528 | 0 | |||
Pituitary adenylate cyclase-activating polypeptide increases [Ca2]i in rat gonadotrophs through an inositol trisphosphate-dependent mechanism | The Journal of biological chemistry | 1994 | 503 | 409 | |||
Characterization of receptor-mediated and store-regulated Ca2+ influx in human neutrophils | Biochemical journal | 1994 | 526 | 0 | |||
Highly co-operative Ca2+ activation of intermediate-conductance K+ channels in granulocytes from a human cell line | Journal of physiology | 1993 | 475 | 0 | |||
Proton channels, plasma membrane potential, and respiratory burst in human neutrophils | European journal of haematology | 1993 | 627 | 0 | |||
Calcium signalling: comparison of the role of Ca2+ influx in excitable endocrine and non-excitable myeloid cells | Advances in second messenger and phosphoprotein research | 1993 | 501 | 0 | |||
Ion channels and receptor-mediated Ca2+ influx in neutrophil granulocytes | Blood cells | 1993 | 480 | 0 | |||
Proton currents in human granulocytes: regulation by membrane potential and intracellular pH | Journal of physiology | 1993 | 479 | 0 | |||
Cyclopiazonic acid depletes intracellular Ca2+ stores and activates an influx pathway for divalent cations in HL-60 cells | The Journal of biological chemistry | 1992 | 489 | 0 | |||
Spontaneous Intracellular Calcium Oscillations and G(s) α Subunit Expression are Inversely Correlated with Secretory Granule Content in Pituitary Cells | Journal of neuroendocrinology | 1992 | 562 | 0 | |||
Regulation of Ca2+ influx in myeloid cells. Role of plasma membrane potential, inositol phosphates, cytosolic free [Ca2+], and filling state of intracellular Ca2+ stores | The Journal of clinical investigation | 1992 | 582 | 0 |