Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store-overload-induced Ca2+ release
Contributeurs/tricesJones, Peter P.; Jiang, Dawei; Bolstad, Jeff; Hunt, Donald J.; Zhang, Lin; Demaurex, Nicolas ; Chen, S R Wayne
Publié dansBiochemical journal, vol. 412, no. 1, p. 171-178
Date de publication2008
Résumé
Mots-clés
- Arrhythmias, Cardiac/*genetics/metabolism
- Biological Transport/genetics
- Calcium/*analysis/*metabolism
- Cells, Cultured
- Death, Sudden, Cardiac/*etiology
- Endoplasmic Reticulum/*chemistry/metabolism
- Humans
- Myocardium/metabolism
- Point Mutation/physiology
- Protein Binding
- Protein Isoforms/metabolism
- Ryanodine Receptor Calcium Release Channel/*genetics/metabolism
- Tacrolimus Binding Protein 1A/metabolism
Structure d'affiliation
Groupe de recherche
Citation (format ISO)
JONES, Peter P. et al. Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store-overload-induced Ca2+ release. In: Biochemical journal, 2008, vol. 412, n° 1, p. 171–178. doi: 10.1042/BJ20071287
Fichiers principaux (1)
Article
Identifiants
- PID : unige:19059
- DOI : 10.1042/BJ20071287
- PMID : 18092949
URL commercialhttp://www.biochemj.org/bj/412/0171/4120171.pdf
ISSN du journal0264-6021