Article (Published version) (159 Kb) - Free access
GRAM marks the spot for STIM. Commentary on "GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells"
|Published in||Cell Calcium. 2018, vol. 73, p. 70-71|
|Abstract||GRAM domain proteins were reported as novel ER-PM tethers defining specific membrane contact sites (MCS) subdomains. GRAMD2a pre-marks the sites occupied by STIM1 at MCS and its ablation impairs STIM1 translocation, but not store-operated Ca2+ entry. We discuss these apparently counterintuitive findings in the context of STIM/ORAI signaling at MCS.|
|Research group||Signaux intracellulaires (210)|
|NUNES-HASLER, Paula, DEMAUREX, Nicolas. GRAM marks the spot for STIM. Commentary on "GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells". In: Cell Calcium, 2018, vol. 73, p. 70-71. https://archive-ouverte.unige.ch/unige:109621|