Reith, Walter | Archive ouverte UNIGE

Title	Published in	Year	Views	Downloads
Magnesium sensing via LFA-1 regulates CD8⁺ T cell effector function	Cell	2022	499	2
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer	Science Advances	2021	467	185
High-throughput screening of human tumor antigen-specific CD4 T cells, including neoantigen-reactive T cells	Clinical Cancer Research	2019	411	4
Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes	Scientific Reports	2019	407	192
Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy	JCI Insight	2019	363	233
Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice	Scientific Reports	2019	327	119
Absence of MHC-II expression by lymph node stromal cells results in autoimmunity	Life Science Alliance	2018	381	186
Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence	Cell Host & Microbe	2016	440	225
IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity	Journal of autoimmunity	2016	626	234
Regulation of Immunity by Butyrophilins	Annual review of immunology	2016	537	1,350
Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis	European Journal of Immunology	2016	554	0
Absence of nonhematopoietic MHC class II expression protects mice from experimental autoimmune myocarditis	European Journal of Immunology	2016	540	451
Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes	The Journal of experimental medicine	2016	747	4
T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels	The Journal of immunology	2016	467	312
Major Histocompatibility Complex Class II Deficiency	Reference Module in Biomedical Sciences, from Encyclopedia of Immunobiology	2016	477	0
Novel Mutation in the Class II Transactivator Associated with Immunodeficiency and Autoimmunity	Journal of clinical immunology	2015	491	312
NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module	PLOS genetics	2015	509	226
TLR3-Mediated CD8+ Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State	The Journal of immunology	2015	490	805
RFX2 Is a Major Transcriptional Regulator of Spermiogenesis	PLOS genetics	2015	524	243
Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells	Science	2015	620	6
RFX transcription factors are essential for hearing in mice	Nature communications	2015	515	222
NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome	International journal of clinical and experimental pathology	2014	659	3
Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering	The Journal of biological chemistry	2014	534	2
Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation	The Journal of immunology	2014	653	586
MHC Class II-Restricted Antigen Presentation by Plasmacytoid Dendritic Cells Drives Proatherogenic T Cell Immunity	Circulation	2014	607	809
Ag-Presenting CpG-Activated pDCs Prime Th17 Cells That Induce Tumor Regression	Cancer research	2014	699	279
Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells	The Journal of immunology	2014	677	3
Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance	The Journal of experimental medicine	2014	743	373
Anti-CD79 antibody induces B cell anergy that protects against autoimmunity	The Journal of immunology	2014	744	0
TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance	PLOS pathogens	2014	707	535
Primary Immunodeficiency Diseases	Primary immunodeficiency diseases : a molecular and genetic approach (Third edition)	2014	447	0
Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis	PloS one	2014	660	337
HEATR2 plays a conserved role in assembly of the ciliary motile apparatus	PLOS genetics	2014	648	377
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity	Journal of bone and mineral research	2014	589	1
Extensive remodeling of DC function by rapid maturation-induced transcriptional silencing	Nucleic acids research	2014	633	350
Characterization of a surrogate murine antibody to model anti-human CD3 therapies	MAbs	2013	606	0
Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction	Tissue antigens	2013	610	5
Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency	The Journal of immunology	2013	653	1
Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output	Nature communications	2013	644	266
Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla	PloS one	2012	611	354
Dampening of arginase 2 expression by microRNA-155 is critical for dendritic cell function	Immunology	2012	461	4
NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells	The Journal of immunology	2012	751	0
The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development	PLOS genetics	2012	680	359
Long-term amelioration of established collagen-induced arthritis achieved with short-term therapy combining anti-CD3 and anti-tumor necrosis factor treatments	Arthritis and rheumatism	2012	563	1
Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research	Frontiers in immunology	2012	708	288
Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo	Nature communications	2012	561	0
Plasmacytoid dendritic cells control T-cell response to chronic viral infection	Proceedings of the National Academy of Sciences of the United States of America	2012	572	0
Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells	The journal of membrane biology	2012	649	341
The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage	Oncogenesis	2012	540	1
Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function	Blood	2011	635	0
Autoimmunity and inflammation are independent of class II transactivator type PIV-dependent class II major histocompatibility complex expression in peripheral tissues during collagen-induced arthritis	Arthritis and rheumatism	2011	634	0
Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice	Journal of autoimmunity	2010	596	2
DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells	Immunome research	2010	616	335
MHC class II molecules enhance Toll-like receptor mediated innate immune responses	PloS one	2010	633	1,211
Control of central self-tolerance induction by autoreactive CD4+ thymocytes	Trends in immunology	2010	627	0
Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?	Brain	2010	554	0
Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation	Brain	2010	557	0
The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression	Diabetes	2010	616	0
MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity	The Journal of experimental medicine	2010	671	1
Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts	Arthritis research & therapy	2010	547	1,493
The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation	The Journal of immunology	2009	678	0
RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies	Journal of cell science	2009	718	2,439
Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice	Gastroenterology	2009	603	1
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells	Proceedings of the National Academy of Sciences of the United States of America	2009	582	0
Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis	The Journal of biological chemistry	2009	542	0
Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site	Nucleic acids research	2009	744	0
Identification of CIITA regulated genetic module dedicated for antigen presentation	PLOS genetics	2008	695	315
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity	Immunity	2008	623	147
The NLR gene family: a standard nomenclature	Immunity	2008	690	0
New dimensions of CIITA	Nature immunology	2008	402	0
Expression of RAB4B, a protein governing endocytic recycling, is co-regulated with MHC class II genes	Nucleic acids research	2007	640	1
Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas	Diabetes	2007	567	0
Transcription-coupled deposition of histone modifications during MHC class II gene activation	Nucleic acids research	2007	621	0
TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis	Brain	2006	526	0
Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease	Tissue antigens	2006	580	0
Revisiting the specificity of the MHC class II transactivator CIITA in vivo	European Journal of Immunology	2006	676	0
Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC	Proceedings of the National Academy of Sciences of the United States of America	2006	488	0
Circulating, soluble forms of major histocompatability complex antigens are not exosome-associated	European Journal of Immunology	2006	599	0
A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells	European journal of neuroscience	2006	597	0
The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells	Molecular and cellular biology	2006	540	0
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts	The FASEB journal	2006	590	0
Regulation of MHC class II gene expression by the class II transactivator	Nature reviews. Immunology	2005	664	0
New functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis study	Molecular and cellular biology	2005	595	0
MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells	Nature immunology	2004	580	0
The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification	Molecular and cellular biology	2004	607	0
In vivo, RFX5 binds differently to the human leucocyte antigen-E, -F, and -G gene promoters and participates in HLA class I protein expression in a cell type-dependent manner	Immunology	2004	570	0
Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes	European Journal of Immunology	2004	556	0
Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA	The Journal of immunology	2004	628	0
The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA	The Journal of biological chemistry	2004	600	0
RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin	Molecular endocrinology	2003	525	0
Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells	Blood	2003	616	0
Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes	The Journal of immunology	2003	638	0
The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation	European Journal of Immunology	2003	545	0
TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes	GLIA	2003	520	0
ComPLEXIN new targets for CIITA	Nature immunology	2003	545	0
Chromatin remodeling and extragenic transcription at the MHC class II locus control region	Nature immunology	2003	581	0
Direct genetic correction as a new method for diagnosis and molecular characterization of MHC class II deficiency	Molecular therapy	2002	607	0
Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation	EMBO journal	2002	649	0
Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene	The Journal of experimental medicine	2001	548	0
Primary immunodeficiency mutation databases	Advances in genetics	2001	625	0
The bare lymphocyte syndrome and the regulation of MHC expression	Annual review of immunology	2001	594	0
Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression	The Journal of experimental medicine	2001	525	0
Expression of the three human major histocompatibility complex class II isotypes exhibits a differential dependence on the transcription factor RFXAP	Molecular and cellular biology	2001	509	0
A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y	Molecular and cellular biology	2000	636	0
Dissection of functional NF-Y-RFX cooperative interactions on the MHC class II Ea promoter	Journal of Molecular Biology	2000	632	0
CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation	Molecular and cellular biology	2000	563	0
Molecular genetics of the Bare lymphocyte syndrome	Reviews in immunogenetics	2000	552	0
Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding	Nature	2000	557	0
Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis	European Journal of Immunology	2000	593	0
Lessons from the bare lymphocyte syndrome: molecular mechanisms regulating MHC class II expression	Immunological reviews	2000	637	0
Founder effect for a 26-bp deletion in the RFXANK gene in North African major histocompatibility complex class II-deficient patients belonging to complementation group B	Immunogenetics	2000	528	0
CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex	Genes & development	2000	463	0
The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression	Microbes and infection	1999	532	0
Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains	Molecular and cellular biology	1999	537	0
CIITA-induced occupation of MHC class II promoters is independent of the cooperative stabilization of the promoter-bound multi-protein complexes	International immunology	1999	584	0
Conditional gene targeting in macrophages and granulocytes using LysMcre mice	Transgenic research	1999	648	1
Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice	Immunity	1998	643	0
Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle	Oncogene	1998	587	0
DNA binding properties of a chemically synthesized DNA binding domain of hRFX1	Nucleic acids research	1998	558	0
Genetic and molecular definition of complementation group D in MHC class II deficiency	Human molecular genetics	1998	601	0
A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients	Nature genetics	1998	609	0
RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency	EMBO journal	1997	611	0
MHC class II deficiency: definition of a new complementation group	Immunobiology	1997	597	0
Analysis of mutations and chromosomal localisation of the gene encoding RFX5, a novel transcription factor affected in major histocompatibility complex class II deficiency	Human mutation	1997	566	0
Mutation of RFXAP, a regulator of MHC class II genes, in primary MHC class II deficiency	The New England journal of medicine	1997	620	0
Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins	Genomics	1996	573	0
Cloning and functional characterization of mammalian homologues of the COPII component Sec23	Molecular biology of the cell	1996	582	0
RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom	Nucleic acids research	1996	531	0
A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity	Molecular and cellular biology	1996	586	0
Major histocompatibility complex class II deficiency: a disease of gene regulation	Advances in immunology	1996	555	0
Regulation of MHC class II genes: lessons from a disease	Annual review of immunology	1996	476	0
A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)	Genes & development	1995	625	0
Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome	The Journal of immunology	1995	548	0
Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes	Immunology today	1995	581	0
Regulation of MHC class II gene expression	Immunobiology	1995	558	0
Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters	The Journal of biological chemistry	1994	597	0
Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y	Proceedings of the National Academy of Sciences of the United States of America	1994	581	0
Functional complementation of major histocompatibility complex class II regulatory mutants by the purified X-box-binding protein RFX	Molecular and cellular biology	1994	608	0
Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA	The Journal of experimental medicine	1994	566	0
RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins	Molecular and cellular biology	1994	640	0
MHC class II-deficient combined immunodeficiency: a disease of gene regulation	Immunological reviews	1994	496	0
Clathrin-coated pit-mediated receptor internalization. Role of internalization signals and receptor mobility	The Journal of biological chemistry	1993	594	0
The different level of expression of HLA-DRB1 and -DRB3 genes is controlled by conserved isotypic differences in promoter sequence	Human immunology	1993	618	0
RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer	Molecular and cellular biology	1993	580	0
The genes for MHC class II regulatory factors RFX1 and RFX2 are located on the short arm of chromosome 19	Genomics	1992	549	0
The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters	Molecular and cellular biology	1992	561	0
Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton	The American journal of pathology	1991	561	0
Regulatory factor-X binding to mutant HLA-DRA promoter sequences	Nucleic acids research	1991	584	0
MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain	Genes & development	1990	610	0
Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family	Molecular and cellular biology	1990	552	0
Inherited immunodeficiency with a defect in a major histocompatibility complex class II promoter-binding protein differs in the chromatin structure of the HLA-DRA gene	Molecular and cellular biology	1989	634	0
Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation	Proceedings of the National Academy of Sciences of the United States of America	1989	490	0
Induction of HLA class II genes by IFN-gamma is transcriptional and requires a trans-acting protein	The Journal of immunology	1989	546	0
Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X	Cell	1988	519	0
Identification of Xenopus laevis mRNAs with homology to repetitive sequences	Nucleic acids research	1984	591	1
Structural analysis of repetitive sequence elements transcribed in early development of Xenopus laevis	Molecular biology reports	1983	504	0
Structural analysis of a cDNA clone from Xenopus laevis containing a repetitive sequence element	Developmental biology	1982	560	0
Organization and sequence analysis of a cluster of repetitive DNA elements from Xenopus laevis	Journal of Molecular Biology	1981	527	0

Magnesium sensing via LFA-1 regulates CD8⁺ T cell effector function

Cell

2022

499

2

Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

Science Advances

2021

467

185

High-throughput screening of human tumor antigen-specific CD4 T cells, including neoantigen-reactive T cells

Clinical Cancer Research

2019

411

4

Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes

Scientific Reports

2019

407

192

Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy

JCI Insight

2019

363

233

Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice

Scientific Reports

2019

327

119

Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

Life Science Alliance

2018

381

186

Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence

Cell Host & Microbe

2016

440

225

IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity

Journal of autoimmunity

2016

626

234

Regulation of Immunity by Butyrophilins

Annual review of immunology

2016

537

1,350

Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis

European Journal of Immunology

2016

554

0

Absence of nonhematopoietic MHC class II expression protects mice from experimental autoimmune myocarditis

European Journal of Immunology

2016

540

451

Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes

The Journal of experimental medicine

2016

747

4

T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels

The Journal of immunology

2016

467

312

Major Histocompatibility Complex Class II Deficiency

Reference Module in Biomedical Sciences, from Encyclopedia of Immunobiology

2016

477

0

Novel Mutation in the Class II Transactivator Associated with Immunodeficiency and Autoimmunity

Journal of clinical immunology

2015

491

312

NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module

PLOS genetics

2015

509

226

TLR3-Mediated CD8+ Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State

The Journal of immunology

2015

490

805

RFX2 Is a Major Transcriptional Regulator of Spermiogenesis

PLOS genetics

2015

524

243

Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells

Science

2015

620

6

RFX transcription factors are essential for hearing in mice

Nature communications

2015

515

222

NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome

International journal of clinical and experimental pathology

2014

659

3

Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering

The Journal of biological chemistry

2014

534

2

Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation

The Journal of immunology

2014

653

586

MHC Class II-Restricted Antigen Presentation by Plasmacytoid Dendritic Cells Drives Proatherogenic T Cell Immunity

Circulation

2014

607

809

Ag-Presenting CpG-Activated pDCs Prime Th17 Cells That Induce Tumor Regression

Cancer research

2014

699

279

Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells

The Journal of immunology

2014

677

3

Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance

The Journal of experimental medicine

2014

743

373

Anti-CD79 antibody induces B cell anergy that protects against autoimmunity

The Journal of immunology

2014

744

0

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance

PLOS pathogens

2014

707

535

Primary Immunodeficiency Diseases

Primary immunodeficiency diseases : a molecular and genetic approach (Third edition)

2014

447

0

Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis

PloS one

2014

660

337

HEATR2 plays a conserved role in assembly of the ciliary motile apparatus

PLOS genetics

2014

648

377

MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity

Journal of bone and mineral research

2014

589

1

Extensive remodeling of DC function by rapid maturation-induced transcriptional silencing

Nucleic acids research

2014

633

350

Characterization of a surrogate murine antibody to model anti-human CD3 therapies

MAbs

2013

606

0

Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction

Tissue antigens

2013

610

5

Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency

The Journal of immunology

2013

653

1

Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output

Nature communications

2013

644

266

Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla

PloS one

2012

611

354

Dampening of arginase 2 expression by microRNA-155 is critical for dendritic cell function

Immunology

2012

461

4

NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells

The Journal of immunology

2012

751

0

The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development

PLOS genetics

2012

680

359

Long-term amelioration of established collagen-induced arthritis achieved with short-term therapy combining anti-CD3 and anti-tumor necrosis factor treatments

Arthritis and rheumatism

2012

563

1

Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research

Frontiers in immunology

2012

708

288

Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo

Nature communications

2012

561

0

Plasmacytoid dendritic cells control T-cell response to chronic viral infection

Proceedings of the National Academy of Sciences of the United States of America

2012

572

0

Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells

The journal of membrane biology

2012

649

341

The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage

Oncogenesis

2012

540

1

Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function

Blood

2011

635

0

Autoimmunity and inflammation are independent of class II transactivator type PIV-dependent class II major histocompatibility complex expression in peripheral tissues during collagen-induced arthritis

Arthritis and rheumatism

2011

634

0

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice

Journal of autoimmunity

2010

596

2

DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells

Immunome research

2010

616

335

MHC class II molecules enhance Toll-like receptor mediated innate immune responses

PloS one

2010

633

1,211

Control of central self-tolerance induction by autoreactive CD4+ thymocytes

Trends in immunology

2010

627

0

Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?

Brain

2010

554

0

Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation

Brain

2010

557

0

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

Diabetes

2010

616

0

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity

The Journal of experimental medicine

2010

671

1

Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts

Arthritis research & therapy

2010

547

1,493

The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation

The Journal of immunology

2009

678

0

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

Journal of cell science

2009

718

2,439

Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice

Gastroenterology

2009

603

1

MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells

Proceedings of the National Academy of Sciences of the United States of America

2009

582

0

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis

The Journal of biological chemistry

2009

542

0

Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site

Nucleic acids research

2009

744

0

Identification of CIITA regulated genetic module dedicated for antigen presentation

PLOS genetics

2008

695

315

Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity

Immunity

2008

623

147

The NLR gene family: a standard nomenclature

Immunity

2008

690

0

New dimensions of CIITA

Nature immunology

2008

402

0

Expression of RAB4B, a protein governing endocytic recycling, is co-regulated with MHC class II genes

Nucleic acids research

2007

640

1

Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas

Diabetes

2007

567

0

Transcription-coupled deposition of histone modifications during MHC class II gene activation

Nucleic acids research

2007

621

0

TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis

Brain

2006

526

0

Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease

Tissue antigens

2006

580

0

Revisiting the specificity of the MHC class II transactivator CIITA in vivo

European Journal of Immunology

2006

676

0

Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC

Proceedings of the National Academy of Sciences of the United States of America

2006

488

0

Circulating, soluble forms of major histocompatability complex antigens are not exosome-associated

European Journal of Immunology

2006

599

0

A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells

European journal of neuroscience

2006

597

0

The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells

Molecular and cellular biology

2006

540

0

Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts

The FASEB journal

2006

590

0

Regulation of MHC class II gene expression by the class II transactivator

Nature reviews. Immunology

2005

664

0

New functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis study

Molecular and cellular biology

2005

595

0

MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells

Nature immunology

2004

580

0

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

Molecular and cellular biology

2004

607

0

In vivo, RFX5 binds differently to the human leucocyte antigen-E, -F, and -G gene promoters and participates in HLA class I protein expression in a cell type-dependent manner

Immunology

2004

570

0

Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes

European Journal of Immunology

2004

556

0

Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA

The Journal of immunology

2004

628

0

The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA

The Journal of biological chemistry

2004

600

0

RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin

Molecular endocrinology

2003

525

0

Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells

Blood

2003

616

0

Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes

The Journal of immunology

2003

638

0

The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation

European Journal of Immunology

2003

545

0

TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes

GLIA

2003

520

0

ComPLEXIN new targets for CIITA

Nature immunology

2003

545

0

Chromatin remodeling and extragenic transcription at the MHC class II locus control region

Nature immunology

2003

581

0

Direct genetic correction as a new method for diagnosis and molecular characterization of MHC class II deficiency

Molecular therapy

2002

607

0

Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation

EMBO journal

2002

649

0

Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene

The Journal of experimental medicine

2001

548

0

Primary immunodeficiency mutation databases

Advances in genetics

2001

625

0

The bare lymphocyte syndrome and the regulation of MHC expression

Annual review of immunology

2001

594

0

Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression

The Journal of experimental medicine

2001

525

0

Expression of the three human major histocompatibility complex class II isotypes exhibits a differential dependence on the transcription factor RFXAP

Molecular and cellular biology

2001

509

0

A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y

Molecular and cellular biology

2000

636

0

Dissection of functional NF-Y-RFX cooperative interactions on the MHC class II Ea promoter

Journal of Molecular Biology

2000

632

0

CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation

Molecular and cellular biology

2000

563

0

Molecular genetics of the Bare lymphocyte syndrome

Reviews in immunogenetics

2000

552

0

Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding

Nature

2000

557

0

Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis

European Journal of Immunology

2000

593

0

Lessons from the bare lymphocyte syndrome: molecular mechanisms regulating MHC class II expression

Immunological reviews

2000

637

0

Founder effect for a 26-bp deletion in the RFXANK gene in North African major histocompatibility complex class II-deficient patients belonging to complementation group B

Immunogenetics

2000

528

0

CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

Genes & development

2000

463

0

The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression

Microbes and infection

1999

532

0

Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains

Molecular and cellular biology

1999

537

0

CIITA-induced occupation of MHC class II promoters is independent of the cooperative stabilization of the promoter-bound multi-protein complexes

International immunology

1999

584

0

Conditional gene targeting in macrophages and granulocytes using LysMcre mice

Transgenic research

1999

648

1

Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice

Immunity

1998

643

0

Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle

Oncogene

1998

587

0

DNA binding properties of a chemically synthesized DNA binding domain of hRFX1

Nucleic acids research

1998

558

0

Genetic and molecular definition of complementation group D in MHC class II deficiency

Human molecular genetics

1998

601

0

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

Nature genetics

1998

609

0

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency

EMBO journal

1997

611

0

MHC class II deficiency: definition of a new complementation group

Immunobiology

1997

597

0

Analysis of mutations and chromosomal localisation of the gene encoding RFX5, a novel transcription factor affected in major histocompatibility complex class II deficiency

Human mutation

1997

566

0

Mutation of RFXAP, a regulator of MHC class II genes, in primary MHC class II deficiency

The New England journal of medicine

1997

620

0

Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins

Genomics

1996

573

0

Cloning and functional characterization of mammalian homologues of the COPII component Sec23

Molecular biology of the cell

1996

582

0

RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom

Nucleic acids research

1996

531

0

A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity

Molecular and cellular biology

1996

586

0

Major histocompatibility complex class II deficiency: a disease of gene regulation

Advances in immunology

1996

555

0

Regulation of MHC class II genes: lessons from a disease

Annual review of immunology

1996

476

0

A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)

Genes & development

1995

625

0

Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome

The Journal of immunology

1995

548

0

Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes

Immunology today

1995

581

0

Regulation of MHC class II gene expression

Immunobiology

1995

558

0

Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters

The Journal of biological chemistry

1994

597

0

Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y

Proceedings of the National Academy of Sciences of the United States of America

1994

581

0

Functional complementation of major histocompatibility complex class II regulatory mutants by the purified X-box-binding protein RFX

Molecular and cellular biology

1994

608

0

Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA

The Journal of experimental medicine

1994

566

0

RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins

Molecular and cellular biology

1994

640

0

MHC class II-deficient combined immunodeficiency: a disease of gene regulation

Immunological reviews

1994

496

0

Clathrin-coated pit-mediated receptor internalization. Role of internalization signals and receptor mobility

The Journal of biological chemistry

1993

594

0

The different level of expression of HLA-DRB1 and -DRB3 genes is controlled by conserved isotypic differences in promoter sequence

Human immunology

1993

618

0

RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer

Molecular and cellular biology

1993

580

0

The genes for MHC class II regulatory factors RFX1 and RFX2 are located on the short arm of chromosome 19

Genomics

1992

549

0

The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters

Molecular and cellular biology

1992

561

0

Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton

The American journal of pathology

1991

561

0

Regulatory factor-X binding to mutant HLA-DRA promoter sequences

Nucleic acids research

1991

584

0

MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain

Genes & development

1990

610

0

Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family

Molecular and cellular biology

1990

552

0

Inherited immunodeficiency with a defect in a major histocompatibility complex class II promoter-binding protein differs in the chromatin structure of the HLA-DRA gene

Molecular and cellular biology

1989

634

0

Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation

Proceedings of the National Academy of Sciences of the United States of America

1989

490

0

Induction of HLA class II genes by IFN-gamma is transcriptional and requires a trans-acting protein

The Journal of immunology

1989

546

0

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X

Cell

1988

519

0

Identification of Xenopus laevis mRNAs with homology to repetitive sequences

Nucleic acids research

1984

591

1

Structural analysis of repetitive sequence elements transcribed in early development of Xenopus laevis

Molecular biology reports

1983

504

0

Structural analysis of a cDNA clone from Xenopus laevis containing a repetitive sequence element

Developmental biology

1982

560

0

Organization and sequence analysis of a cluster of repetitive DNA elements from Xenopus laevis

Journal of Molecular Biology

1981

527

0