Reith, Walter | Archive ouverte UNIGE

Title	Published in	Year	Views	Downloads
Magnesium sensing via LFA-1 regulates CD8⁺ T cell effector function	Cell	2022	529	2
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer	Science Advances	2021	492	279
High-throughput screening of human tumor antigen-specific CD4 T cells, including neoantigen-reactive T cells	Clinical Cancer Research	2019	443	4
Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes	Scientific Reports	2019	422	199
Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy	JCI Insight	2019	387	246
Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice	Scientific Reports	2019	343	139
Absence of MHC-II expression by lymph node stromal cells results in autoimmunity	Life Science Alliance	2018	397	206
Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence	Cell Host & Microbe	2016	462	244
IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity	Journal of autoimmunity	2016	646	264
Regulation of Immunity by Butyrophilins	Annual review of immunology	2016	547	1,438
Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis	European Journal of Immunology	2016	585	0
Absence of nonhematopoietic MHC class II expression protects mice from experimental autoimmune myocarditis	European Journal of Immunology	2016	552	469
Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes	The Journal of experimental medicine	2016	778	4
T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels	The Journal of immunology	2016	488	317
Major Histocompatibility Complex Class II Deficiency	Reference Module in Biomedical Sciences, from Encyclopedia of Immunobiology	2016	490	0
Novel Mutation in the Class II Transactivator Associated with Immunodeficiency and Autoimmunity	Journal of clinical immunology	2015	511	327
NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module	PLOS genetics	2015	542	241
TLR3-Mediated CD8+ Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State	The Journal of immunology	2015	513	832
RFX2 Is a Major Transcriptional Regulator of Spermiogenesis	PLOS genetics	2015	539	251
Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells	Science	2015	637	6
RFX transcription factors are essential for hearing in mice	Nature communications	2015	531	234
NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome	International journal of clinical and experimental pathology	2014	691	3
Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering	The Journal of biological chemistry	2014	563	2
Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation	The Journal of immunology	2014	676	664
MHC Class II-Restricted Antigen Presentation by Plasmacytoid Dendritic Cells Drives Proatherogenic T Cell Immunity	Circulation	2014	632	830
Ag-Presenting CpG-Activated pDCs Prime Th17 Cells That Induce Tumor Regression	Cancer research	2014	714	283
Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells	The Journal of immunology	2014	692	3
Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance	The Journal of experimental medicine	2014	765	383
Anti-CD79 antibody induces B cell anergy that protects against autoimmunity	The Journal of immunology	2014	771	0
TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance	PLOS pathogens	2014	733	542
Primary Immunodeficiency Diseases	Primary immunodeficiency diseases : a molecular and genetic approach (Third edition)	2014	465	0
Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis	PloS one	2014	680	356
HEATR2 plays a conserved role in assembly of the ciliary motile apparatus	PLOS genetics	2014	668	385
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity	Journal of bone and mineral research	2014	611	1
Extensive remodeling of DC function by rapid maturation-induced transcriptional silencing	Nucleic acids research	2014	653	358
Characterization of a surrogate murine antibody to model anti-human CD3 therapies	MAbs	2013	638	0
Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction	Tissue antigens	2013	623	5
Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency	The Journal of immunology	2013	672	1
Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output	Nature communications	2013	659	278
Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla	PloS one	2012	634	362
Dampening of arginase 2 expression by microRNA-155 is critical for dendritic cell function	Immunology	2012	476	4
NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells	The Journal of immunology	2012	767	0
The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development	PLOS genetics	2012	704	373
Long-term amelioration of established collagen-induced arthritis achieved with short-term therapy combining anti-CD3 and anti-tumor necrosis factor treatments	Arthritis and rheumatism	2012	616	1
Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research	Frontiers in immunology	2012	738	295
Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo	Nature communications	2012	581	0
Plasmacytoid dendritic cells control T-cell response to chronic viral infection	Proceedings of the National Academy of Sciences of the United States of America	2012	607	0
Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells	The journal of membrane biology	2012	669	363
The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage	Oncogenesis	2012	552	1
Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function	Blood	2011	651	0
Autoimmunity and inflammation are independent of class II transactivator type PIV-dependent class II major histocompatibility complex expression in peripheral tissues during collagen-induced arthritis	Arthritis and rheumatism	2011	643	0
Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice	Journal of autoimmunity	2010	624	2
DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells	Immunome research	2010	632	354
MHC class II molecules enhance Toll-like receptor mediated innate immune responses	PloS one	2010	661	1,223
Control of central self-tolerance induction by autoreactive CD4+ thymocytes	Trends in immunology	2010	654	0
Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?	Brain	2010	574	0
Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation	Brain	2010	576	0
The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression	Diabetes	2010	636	0
MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity	The Journal of experimental medicine	2010	693	1
Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts	Arthritis research & therapy	2010	566	1,500
The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation	The Journal of immunology	2009	703	0
RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies	Journal of cell science	2009	743	2,517
Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice	Gastroenterology	2009	622	1
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells	Proceedings of the National Academy of Sciences of the United States of America	2009	595	0
Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis	The Journal of biological chemistry	2009	557	0
Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site	Nucleic acids research	2009	761	0
Identification of CIITA regulated genetic module dedicated for antigen presentation	PLOS genetics	2008	717	327
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity	Immunity	2008	644	147
The NLR gene family: a standard nomenclature	Immunity	2008	718	0
New dimensions of CIITA	Nature immunology	2008	414	0
Expression of RAB4B, a protein governing endocytic recycling, is co-regulated with MHC class II genes	Nucleic acids research	2007	665	1
Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas	Diabetes	2007	587	0
Transcription-coupled deposition of histone modifications during MHC class II gene activation	Nucleic acids research	2007	633	0
TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis	Brain	2006	546	0
Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease	Tissue antigens	2006	603	0
Revisiting the specificity of the MHC class II transactivator CIITA in vivo	European Journal of Immunology	2006	693	0
Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC	Proceedings of the National Academy of Sciences of the United States of America	2006	511	0
Circulating, soluble forms of major histocompatability complex antigens are not exosome-associated	European Journal of Immunology	2006	617	0
A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells	European journal of neuroscience	2006	618	0
The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells	Molecular and cellular biology	2006	572	0
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts	The FASEB journal	2006	605	0
Regulation of MHC class II gene expression by the class II transactivator	Nature reviews. Immunology	2005	681	0
New functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis study	Molecular and cellular biology	2005	609	0
MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells	Nature immunology	2004	595	0
The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification	Molecular and cellular biology	2004	623	0
In vivo, RFX5 binds differently to the human leucocyte antigen-E, -F, and -G gene promoters and participates in HLA class I protein expression in a cell type-dependent manner	Immunology	2004	628	0
Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes	European Journal of Immunology	2004	574	0
Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA	The Journal of immunology	2004	649	0
The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA	The Journal of biological chemistry	2004	611	0
RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin	Molecular endocrinology	2003	555	0
Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells	Blood	2003	629	0
Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes	The Journal of immunology	2003	665	0
The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation	European Journal of Immunology	2003	565	0
TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes	GLIA	2003	533	0
ComPLEXIN new targets for CIITA	Nature immunology	2003	563	0
Chromatin remodeling and extragenic transcription at the MHC class II locus control region	Nature immunology	2003	599	0
Direct genetic correction as a new method for diagnosis and molecular characterization of MHC class II deficiency	Molecular therapy	2002	634	0
Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation	EMBO journal	2002	675	0
Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene	The Journal of experimental medicine	2001	560	0
Primary immunodeficiency mutation databases	Advances in genetics	2001	643	0
The bare lymphocyte syndrome and the regulation of MHC expression	Annual review of immunology	2001	625	0
Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression	The Journal of experimental medicine	2001	549	0
Expression of the three human major histocompatibility complex class II isotypes exhibits a differential dependence on the transcription factor RFXAP	Molecular and cellular biology	2001	523	0
A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y	Molecular and cellular biology	2000	655	0
Dissection of functional NF-Y-RFX cooperative interactions on the MHC class II Ea promoter	Journal of Molecular Biology	2000	658	0
CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation	Molecular and cellular biology	2000	603	0
Molecular genetics of the Bare lymphocyte syndrome	Reviews in immunogenetics	2000	564	0
Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding	Nature	2000	579	0
Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis	European Journal of Immunology	2000	613	0
Lessons from the bare lymphocyte syndrome: molecular mechanisms regulating MHC class II expression	Immunological reviews	2000	659	0
Founder effect for a 26-bp deletion in the RFXANK gene in North African major histocompatibility complex class II-deficient patients belonging to complementation group B	Immunogenetics	2000	551	0
CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex	Genes & development	2000	480	0
The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression	Microbes and infection	1999	590	0
Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains	Molecular and cellular biology	1999	559	0
CIITA-induced occupation of MHC class II promoters is independent of the cooperative stabilization of the promoter-bound multi-protein complexes	International immunology	1999	597	0
Conditional gene targeting in macrophages and granulocytes using LysMcre mice	Transgenic research	1999	698	1
Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice	Immunity	1998	661	0
Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle	Oncogene	1998	607	0
DNA binding properties of a chemically synthesized DNA binding domain of hRFX1	Nucleic acids research	1998	583	0
Genetic and molecular definition of complementation group D in MHC class II deficiency	Human molecular genetics	1998	629	0
A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients	Nature genetics	1998	627	0
RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency	EMBO journal	1997	640	0
MHC class II deficiency: definition of a new complementation group	Immunobiology	1997	612	0
Analysis of mutations and chromosomal localisation of the gene encoding RFX5, a novel transcription factor affected in major histocompatibility complex class II deficiency	Human mutation	1997	613	0
Mutation of RFXAP, a regulator of MHC class II genes, in primary MHC class II deficiency	The New England journal of medicine	1997	635	0
Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins	Genomics	1996	597	0
Cloning and functional characterization of mammalian homologues of the COPII component Sec23	Molecular biology of the cell	1996	593	0
RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom	Nucleic acids research	1996	566	0
A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity	Molecular and cellular biology	1996	604	0
Major histocompatibility complex class II deficiency: a disease of gene regulation	Advances in immunology	1996	605	0
Regulation of MHC class II genes: lessons from a disease	Annual review of immunology	1996	501	0
A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)	Genes & development	1995	642	0
Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome	The Journal of immunology	1995	567	0
Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes	Immunology today	1995	597	0
Regulation of MHC class II gene expression	Immunobiology	1995	591	0
Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters	The Journal of biological chemistry	1994	613	0
Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y	Proceedings of the National Academy of Sciences of the United States of America	1994	598	0
Functional complementation of major histocompatibility complex class II regulatory mutants by the purified X-box-binding protein RFX	Molecular and cellular biology	1994	667	0
Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA	The Journal of experimental medicine	1994	583	0
RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins	Molecular and cellular biology	1994	662	0
MHC class II-deficient combined immunodeficiency: a disease of gene regulation	Immunological reviews	1994	505	0
Clathrin-coated pit-mediated receptor internalization. Role of internalization signals and receptor mobility	The Journal of biological chemistry	1993	614	0
The different level of expression of HLA-DRB1 and -DRB3 genes is controlled by conserved isotypic differences in promoter sequence	Human immunology	1993	642	0
RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer	Molecular and cellular biology	1993	598	0
The genes for MHC class II regulatory factors RFX1 and RFX2 are located on the short arm of chromosome 19	Genomics	1992	571	0
The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters	Molecular and cellular biology	1992	576	0
Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton	The American journal of pathology	1991	578	0
Regulatory factor-X binding to mutant HLA-DRA promoter sequences	Nucleic acids research	1991	604	0
MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain	Genes & development	1990	630	0
Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family	Molecular and cellular biology	1990	570	0
Inherited immunodeficiency with a defect in a major histocompatibility complex class II promoter-binding protein differs in the chromatin structure of the HLA-DRA gene	Molecular and cellular biology	1989	665	0
Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation	Proceedings of the National Academy of Sciences of the United States of America	1989	506	0
Induction of HLA class II genes by IFN-gamma is transcriptional and requires a trans-acting protein	The Journal of immunology	1989	584	0
Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X	Cell	1988	540	0
Identification of Xenopus laevis mRNAs with homology to repetitive sequences	Nucleic acids research	1984	606	1
Structural analysis of repetitive sequence elements transcribed in early development of Xenopus laevis	Molecular biology reports	1983	512	0
Structural analysis of a cDNA clone from Xenopus laevis containing a repetitive sequence element	Developmental biology	1982	582	0
Organization and sequence analysis of a cluster of repetitive DNA elements from Xenopus laevis	Journal of Molecular Biology	1981	536	0

Magnesium sensing via LFA-1 regulates CD8⁺ T cell effector function

Cell

2022

529

2

Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

Science Advances

2021

492

279

High-throughput screening of human tumor antigen-specific CD4 T cells, including neoantigen-reactive T cells

Clinical Cancer Research

2019

443

4

Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes

Scientific Reports

2019

422

199

Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy

JCI Insight

2019

387

246

Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice

Scientific Reports

2019

343

139

Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

Life Science Alliance

2018

397

206

Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence

Cell Host & Microbe

2016

462

244

IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity

Journal of autoimmunity

2016

646

264

Regulation of Immunity by Butyrophilins

Annual review of immunology

2016

547

1,438

Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis

European Journal of Immunology

2016

585

0

Absence of nonhematopoietic MHC class II expression protects mice from experimental autoimmune myocarditis

European Journal of Immunology

2016

552

469

Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes

The Journal of experimental medicine

2016

778

4

T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels

The Journal of immunology

2016

488

317

Major Histocompatibility Complex Class II Deficiency

Reference Module in Biomedical Sciences, from Encyclopedia of Immunobiology

2016

490

0

Novel Mutation in the Class II Transactivator Associated with Immunodeficiency and Autoimmunity

Journal of clinical immunology

2015

511

327

NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module

PLOS genetics

2015

542

241

TLR3-Mediated CD8+ Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State

The Journal of immunology

2015

513

832

RFX2 Is a Major Transcriptional Regulator of Spermiogenesis

PLOS genetics

2015

539

251

Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells

Science

2015

637

6

RFX transcription factors are essential for hearing in mice

Nature communications

2015

531

234

NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome

International journal of clinical and experimental pathology

2014

691

3

Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering

The Journal of biological chemistry

2014

563

2

Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation

The Journal of immunology

2014

676

664

MHC Class II-Restricted Antigen Presentation by Plasmacytoid Dendritic Cells Drives Proatherogenic T Cell Immunity

Circulation

2014

632

830

Ag-Presenting CpG-Activated pDCs Prime Th17 Cells That Induce Tumor Regression

Cancer research

2014

714

283

Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells

The Journal of immunology

2014

692

3

Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance

The Journal of experimental medicine

2014

765

383

Anti-CD79 antibody induces B cell anergy that protects against autoimmunity

The Journal of immunology

2014

771

0

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance

PLOS pathogens

2014

733

542

Primary Immunodeficiency Diseases

Primary immunodeficiency diseases : a molecular and genetic approach (Third edition)

2014

465

0

Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis

PloS one

2014

680

356

HEATR2 plays a conserved role in assembly of the ciliary motile apparatus

PLOS genetics

2014

668

385

MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity

Journal of bone and mineral research

2014

611

1

Extensive remodeling of DC function by rapid maturation-induced transcriptional silencing

Nucleic acids research

2014

653

358

Characterization of a surrogate murine antibody to model anti-human CD3 therapies

MAbs

2013

638

0

Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction

Tissue antigens

2013

623

5

Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency

The Journal of immunology

2013

672

1

Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output

Nature communications

2013

659

278

Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla

PloS one

2012

634

362

Dampening of arginase 2 expression by microRNA-155 is critical for dendritic cell function

Immunology

2012

476

4

NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells

The Journal of immunology

2012

767

0

The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development

PLOS genetics

2012

704

373

Long-term amelioration of established collagen-induced arthritis achieved with short-term therapy combining anti-CD3 and anti-tumor necrosis factor treatments

Arthritis and rheumatism

2012

616

1

Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research

Frontiers in immunology

2012

738

295

Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo

Nature communications

2012

581

0

Plasmacytoid dendritic cells control T-cell response to chronic viral infection

Proceedings of the National Academy of Sciences of the United States of America

2012

607

0

Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells

The journal of membrane biology

2012

669

363

The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage

Oncogenesis

2012

552

1

Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function

Blood

2011

651

0

Autoimmunity and inflammation are independent of class II transactivator type PIV-dependent class II major histocompatibility complex expression in peripheral tissues during collagen-induced arthritis

Arthritis and rheumatism

2011

643

0

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice

Journal of autoimmunity

2010

624

2

DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells

Immunome research

2010

632

354

MHC class II molecules enhance Toll-like receptor mediated innate immune responses

PloS one

2010

661

1,223

Control of central self-tolerance induction by autoreactive CD4+ thymocytes

Trends in immunology

2010

654

0

Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?

Brain

2010

574

0

Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation

Brain

2010

576

0

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

Diabetes

2010

636

0

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity

The Journal of experimental medicine

2010

693

1

Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts

Arthritis research & therapy

2010

566

1,500

The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation

The Journal of immunology

2009

703

0

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

Journal of cell science

2009

743

2,517

Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice

Gastroenterology

2009

622

1

MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells

Proceedings of the National Academy of Sciences of the United States of America

2009

595

0

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis

The Journal of biological chemistry

2009

557

0

Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site

Nucleic acids research

2009

761

0

Identification of CIITA regulated genetic module dedicated for antigen presentation

PLOS genetics

2008

717

327

Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity

Immunity

2008

644

147

The NLR gene family: a standard nomenclature

Immunity

2008

718

0

New dimensions of CIITA

Nature immunology

2008

414

0

Expression of RAB4B, a protein governing endocytic recycling, is co-regulated with MHC class II genes

Nucleic acids research

2007

665

1

Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas

Diabetes

2007

587

0

Transcription-coupled deposition of histone modifications during MHC class II gene activation

Nucleic acids research

2007

633

0

TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis

Brain

2006

546

0

Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease

Tissue antigens

2006

603

0

Revisiting the specificity of the MHC class II transactivator CIITA in vivo

European Journal of Immunology

2006

693

0

Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC

Proceedings of the National Academy of Sciences of the United States of America

2006

511

0

Circulating, soluble forms of major histocompatability complex antigens are not exosome-associated

European Journal of Immunology

2006

617

0

A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells

European journal of neuroscience

2006

618

0

The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells

Molecular and cellular biology

2006

572

0

Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts

The FASEB journal

2006

605

0

Regulation of MHC class II gene expression by the class II transactivator

Nature reviews. Immunology

2005

681

0

New functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis study

Molecular and cellular biology

2005

609

0

MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells

Nature immunology

2004

595

0

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

Molecular and cellular biology

2004

623

0

In vivo, RFX5 binds differently to the human leucocyte antigen-E, -F, and -G gene promoters and participates in HLA class I protein expression in a cell type-dependent manner

Immunology

2004

628

0

Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes

European Journal of Immunology

2004

574

0

Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA

The Journal of immunology

2004

649

0

The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA

The Journal of biological chemistry

2004

611

0

RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin

Molecular endocrinology

2003

555

0

Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells

Blood

2003

629

0

Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes

The Journal of immunology

2003

665

0

The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation

European Journal of Immunology

2003

565

0

TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes

GLIA

2003

533

0

ComPLEXIN new targets for CIITA

Nature immunology

2003

563

0

Chromatin remodeling and extragenic transcription at the MHC class II locus control region

Nature immunology

2003

599

0

Direct genetic correction as a new method for diagnosis and molecular characterization of MHC class II deficiency

Molecular therapy

2002

634

0

Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation

EMBO journal

2002

675

0

Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene

The Journal of experimental medicine

2001

560

0

Primary immunodeficiency mutation databases

Advances in genetics

2001

643

0

The bare lymphocyte syndrome and the regulation of MHC expression

Annual review of immunology

2001

625

0

Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression

The Journal of experimental medicine

2001

549

0

Expression of the three human major histocompatibility complex class II isotypes exhibits a differential dependence on the transcription factor RFXAP

Molecular and cellular biology

2001

523

0

A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y

Molecular and cellular biology

2000

655

0

Dissection of functional NF-Y-RFX cooperative interactions on the MHC class II Ea promoter

Journal of Molecular Biology

2000

658

0

CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation

Molecular and cellular biology

2000

603

0

Molecular genetics of the Bare lymphocyte syndrome

Reviews in immunogenetics

2000

564

0

Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding

Nature

2000

579

0

Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis

European Journal of Immunology

2000

613

0

Lessons from the bare lymphocyte syndrome: molecular mechanisms regulating MHC class II expression

Immunological reviews

2000

659

0

Founder effect for a 26-bp deletion in the RFXANK gene in North African major histocompatibility complex class II-deficient patients belonging to complementation group B

Immunogenetics

2000

551

0

CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

Genes & development

2000

480

0

The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression

Microbes and infection

1999

590

0

Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains

Molecular and cellular biology

1999

559

0

CIITA-induced occupation of MHC class II promoters is independent of the cooperative stabilization of the promoter-bound multi-protein complexes

International immunology

1999

597

0

Conditional gene targeting in macrophages and granulocytes using LysMcre mice

Transgenic research

1999

698

1

Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice

Immunity

1998

661

0

Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle

Oncogene

1998

607

0

DNA binding properties of a chemically synthesized DNA binding domain of hRFX1

Nucleic acids research

1998

583

0

Genetic and molecular definition of complementation group D in MHC class II deficiency

Human molecular genetics

1998

629

0

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

Nature genetics

1998

627

0

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency

EMBO journal

1997

640

0

MHC class II deficiency: definition of a new complementation group

Immunobiology

1997

612

0

Analysis of mutations and chromosomal localisation of the gene encoding RFX5, a novel transcription factor affected in major histocompatibility complex class II deficiency

Human mutation

1997

613

0

Mutation of RFXAP, a regulator of MHC class II genes, in primary MHC class II deficiency

The New England journal of medicine

1997

635

0

Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins

Genomics

1996

597

0

Cloning and functional characterization of mammalian homologues of the COPII component Sec23

Molecular biology of the cell

1996

593

0

RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom

Nucleic acids research

1996

566

0

A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity

Molecular and cellular biology

1996

604

0

Major histocompatibility complex class II deficiency: a disease of gene regulation

Advances in immunology

1996

605

0

Regulation of MHC class II genes: lessons from a disease

Annual review of immunology

1996

501

0

A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)

Genes & development

1995

642

0

Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome

The Journal of immunology

1995

567

0

Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes

Immunology today

1995

597

0

Regulation of MHC class II gene expression

Immunobiology

1995

591

0

Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters

The Journal of biological chemistry

1994

613

0

Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y

Proceedings of the National Academy of Sciences of the United States of America

1994

598

0

Functional complementation of major histocompatibility complex class II regulatory mutants by the purified X-box-binding protein RFX

Molecular and cellular biology

1994

667

0

Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA

The Journal of experimental medicine

1994

583

0

RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins

Molecular and cellular biology

1994

662

0

MHC class II-deficient combined immunodeficiency: a disease of gene regulation

Immunological reviews

1994

505

0

Clathrin-coated pit-mediated receptor internalization. Role of internalization signals and receptor mobility

The Journal of biological chemistry

1993

614

0

The different level of expression of HLA-DRB1 and -DRB3 genes is controlled by conserved isotypic differences in promoter sequence

Human immunology

1993

642

0

RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer

Molecular and cellular biology

1993

598

0

The genes for MHC class II regulatory factors RFX1 and RFX2 are located on the short arm of chromosome 19

Genomics

1992

571

0

The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters

Molecular and cellular biology

1992

576

0

Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton

The American journal of pathology

1991

578

0

Regulatory factor-X binding to mutant HLA-DRA promoter sequences

Nucleic acids research

1991

604

0

MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain

Genes & development

1990

630

0

Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family

Molecular and cellular biology

1990

570

0

Inherited immunodeficiency with a defect in a major histocompatibility complex class II promoter-binding protein differs in the chromatin structure of the HLA-DRA gene

Molecular and cellular biology

1989

665

0

Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation

Proceedings of the National Academy of Sciences of the United States of America

1989

506

0

Induction of HLA class II genes by IFN-gamma is transcriptional and requires a trans-acting protein

The Journal of immunology

1989

584

0

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X

Cell

1988

540

0

Identification of Xenopus laevis mRNAs with homology to repetitive sequences

Nucleic acids research

1984

606

1

Structural analysis of repetitive sequence elements transcribed in early development of Xenopus laevis

Molecular biology reports

1983

512

0

Structural analysis of a cDNA clone from Xenopus laevis containing a repetitive sequence element

Developmental biology

1982

582

0

Organization and sequence analysis of a cluster of repetitive DNA elements from Xenopus laevis

Journal of Molecular Biology

1981

536

0