| Phosphorylation of the Hsp90 Co-Chaperone Hop Changes its Conformational Dynamics and Biological Function | Journal of Molecular Biology | | | 2023 | 157 | 1 |
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| Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer | Cellular and molecular life sciences | | | 2023 | 131 | 415 |
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| CRISPR-Cas9 screen reveals a role of purine synthesis for estrogen receptor α activity and tamoxifen resistance of breast cancer cells | Science advances | | | 2023 | 100 | 596 |
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| Hsf1 and the molecular chaperone Hsp90 support a ‘rewiring stress response’ leading to an adaptive cell size increase in chronic stress | eLife | | | 2023 | 109 | 262 |
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| Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance | Biomolecules | | | 2022 | 178 | 986 |
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| The Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and Inhibitors | Biomolecules | | | 2022 | 119 | 476 |
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| Hyperactivation of MAPK Induces Tamoxifen Resistance in SPRED2-Deficient ERα-Positive Breast Cancer | Cancers | | | 2022 | 222 | 443 |
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| Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis | Nature communications | | | 2022 | 196 | 122 |
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| Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life | Nature communications | | | 2022 | 332 | 565 |
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| The Hsp70–Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration | Cellular and molecular life sciences | | | 2021 | 14 | 96 |
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| H90-10 single-chain antibody recognizes Hsp90beta by immunoprecipitation and Western blotting | Antibody reports | | | 2021 | 198 | 159 |
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| The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation | Nature Communications | | | 2020 | 316 | 260 |
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| The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis | BMC Biology | | | 2020 | 366 | 193 |
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| Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial | Analytica Chimica Acta | | | 2020 | 435 | 1 |
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| Genetic ablation of MiR-22 fosters diet-induced obesity and NAFLD development | Journal of Personalized Medicine | | | 2020 | 366 | 221 |
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| Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling | Nature Communications | | | 2019 | 538 | 297 |
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| AI179 single-chain antibody recognizes the Myc tag by Western blotting | Antibody Reports | | | 2019 | 342 | 342 |
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| The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity | PloS one | | | 2019 | 516 | 368 |
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| A scoring approach for multi-platform acquisition in metabolomics | Journal of Chromatography. A | | | 2019 | 495 | 1 |
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| AF291 and AE391 single-chain antibodies recognize the HA tag by Western blotting | Antibody Reports | | | 2019 | 544 | 261 |
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| ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1 | Life Science Alliance | | | 2018 | 458 | 212 |
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| Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development | Cell Stress and Chaperones | | | 2018 | 515 | 618 |
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| Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes | Scientific Reports | | | 2018 | 442 | 229 |
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| A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells | Oncotarget | | | 2017 | 548 | 286 |
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| Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease | Brain | | | 2017 | 518 | 0 |
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| Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol | ACS Medicinal Chemistry Letters | | | 2017 | 517 | 0 |
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| H2B monoubiquitination: t'ub or not t'ub for inducible enhancers | Transcription | | | 2017 | 531 | 335 |
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| Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model | Oncotarget | | | 2017 | 532 | 274 |
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| Dendrogenin A drives LXR to trigger lethal autophagy in cancers | Nature Communications | | | 2017 | 591 | 469 |
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| Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry | PLOS ONE | | | 2017 | 562 | 498 |
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| Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23 | PloS one | | | 2017 | 467 | 269 |
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| A remodeled Hsp90 molecular chaperone ensemble with the novel co-chaperone Aarsd1 is required for muscle differentiation | Molecular and cellular biology | | | 2016 | 529 | 363 |
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| Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers | Molecular cell | | | 2016 | 607 | 519 |
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| GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response | Scientific reports | | | 2016 | 609 | 399 |
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| LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP | Nucleic acids research | | | 2016 | 596 | 465 |
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| Unusual Suspects in the Twilight Zone Between the Hsp90 Interactome and Carcinogenesis | Hsp90 in Cancer: Beyond the Usual Suspects | | | 2016 | 626 | 1 |
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| Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles | Journal of medicinal chemistry | | | 2016 | 512 | 0 |
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| Minireview: Tipping the balance: ligand-independent activation of steroid receptors | Molecular endocrinology | | | 2015 | 880 | 1 |
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| Overview of molecular chaperones in health and disease | Inhibitors of Molecular Chaperones as Therapeutic Agents | | | 2014 | 589 | 1 |
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| Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors | Journal of medicinal chemistry | | | 2014 | 732 | 878 |
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| A global view of the proteome perturbations by Hsp90 inhibitors | The Molecular Chaperones Interaction Networks in Protein Folding and Degradation | | | 2014 | 726 | 0 |
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| Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells | Trends in cell biology | | | 2014 | 706 | 45 |
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| Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis | Proceedings of the National Academy of Sciences of the United States of America | | | 2013 | 1,018 | 729 |
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| Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on the T-Cell Proteome Have Implications for Anti-Cancer Therapy | PloS one | | | 2013 | 716 | 376 |
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| The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter | The Journal of experimental medicine | | | 2013 | 813 | 695 |
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| Preface to Hsp90 | Biochimica et biophysica acta. Molecular cell research | | | 2012 | 622 | 440 |
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| An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine | PloS one | | | 2011 | 626 | 415 |
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| Influenza Virus Infection Induces the Nuclear Relocalization of the Hsp90 Co-Chaperone p23 and Inhibits the Glucocorticoid Receptor Response | PloS one | | | 2011 | 796 | 455 |
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| The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes | PloS one | | | 2011 | 578 | 661 |
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| Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation | BioData mining | | | 2011 | 706 | 1,183 |
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| CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP | Genes & development | | | 2010 | 637 | 0 |
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| Multidirectional interplay between nuclear receptors and microRNAs | Current opinion in pharmacology | | | 2010 | 607 | 0 |
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| Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility | Biochimica et biophysica acta | | | 2010 | 552 | 0 |
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| The unfolding stories of GPR30, a new membrane-bound estrogen receptor | Journal of Endocrinology | | | 2010 | 1,031 | 0 |
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| The molecular chaperone Hsp90alpha is required for meiotic progression of spermatocytes beyond pachytene in the mouse | PloS one | | | 2010 | 785 | 549 |
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| miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA | Molecular and cellular biology | | | 2009 | 669 | 0 |
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| The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities | Molecular and biochemical parasitology | | | 2009 | 815 | 0 |
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| Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF | EMBO journal | | | 2009 | 1,394 | 1,051 |
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| Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells | Endocrinology | | | 2008 | 1,130 | 0 |
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| Genomics of signaling crosstalk of estrogen receptor alpha in breast cancer cells | PloS one | | | 2008 | 585 | 332 |
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| A stress protein interface of innate immunity | EMBO reports | | | 2008 | 641 | 257 |
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| The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation | Immunity | | | 2008 | 588 | 0 |
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| p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity | Molecular and cellular biology | | | 2008 | 749 | 0 |
|
| The glucocorticoid responses are shaped by molecular chaperones | Molecular and cellular endocrinology | | | 2007 | 579 | 0 |
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| Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome | Digestive diseases and sciences | | | 2007 | 638 | 585 |
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| Chaperoning steroid hormone action | Trends in endocrinology and metabolism | | | 2006 | 663 | 0 |
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| Fungi and animals may share a common ancestor to nuclear receptors | Proceedings of the National Academy of Sciences of the United States of America | | | 2006 | 578 | 0 |
|
| Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90 | Experimental cell research | | | 2006 | 573 | 1 |
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| The cell-specific activity of the estrogen receptor alpha may be fine-tuned by phosphorylation-induced structural gymnastics | Nuclear receptor signaling | | | 2006 | 630 | 271 |
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| The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells | Molecular endocrinology | | | 2006 | 909 | 0 |
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| 2-color photobleaching experiments reveal distinct intracellular dynamics of two components of the Hsp90 complex | Experimental cell research | | | 2006 | 637 | 2 |
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| The Hsp90 cochaperone p23 is essential for perinatal survival | Molecular and cellular biology | | | 2006 | 669 | 1 |
|
| [Retracted] 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30 | Molecular pharmacology | | | 2006 | 1,124 | 0 |
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| Bioluminescent yeast assays for detecting estrogenic and androgenic activity in different matrices | Chemosphere | | | 2005 | 631 | 1 |
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| LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes | Human molecular genetics | | | 2005 | 672 | 0 |
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| siRNA production by in vitro transcription | Gene silencing by RNA interference : technology and application | | | 2005 | 640 | 1 |
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| A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90alpha | Biochemical and biophysical research communications | | | 2005 | 587 | 2 |
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| SPBP is a phosphoserine-specific repressor of estrogen receptor alpha | Molecular and cellular biology | | | 2005 | 585 | 0 |
|
| The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells | The Journal of biological chemistry | | | 2004 | 839 | 0 |
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| A web application to manage a database for liquid nitrogen tanks | Immunology and cell biology | | | 2004 | 609 | 1 |
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| A recombinant yeast strain as a short term bioassay to assess estrogen-like activity of xenobiotics | Annali di igiene medicina preventiva e di comunità | | | 2004 | 476 | 0 |
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| The protein kinase PKR: a molecular clock that sequentially activates survival and death programs | EMBO journal | | | 2004 | 616 | 0 |
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| TROD: T7 RNAi oligo designer | Nucleic acids research | | | 2004 | 694 | 446 |
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| Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells | Journal of molecular endocrinology | | | 2004 | 637 | 0 |
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| Hsp90 invades the outside | Nature cell biology | | | 2004 | 539 | 0 |
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| The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo | EMBO journal | | | 2003 | 628 | 0 |
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| Molecular mechanisms of cross-talk between growth factors and nuclear receptor signaling | Pure and applied chemistry | | | 2003 | 632 | 647 |
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| Cdc37 goes beyond Hsp90 and kinases | Cell stress & chaperones | | | 2003 | 637 | 3 |
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| Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation | Molecular and cellular biology | | | 2002 | 562 | 0 |
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| Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells | Molecular and cellular endocrinology | | | 2002 | 662 | 0 |
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| Heat-shock protein 90, a chaperone for folding and regulation | Cellular and molecular life sciences | | | 2002 | 682 | 2 |
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| The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically | Biological chemistry | | | 2002 | 667 | 0 |
|
| RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase | Nucleic acids research | | | 2002 | 610 | 417 |
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| The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR | EMBO journal | | | 2001 | 656 | 0 |
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| Hsp104 interacts with Hsp90 cochaperones in respiring yeast | Molecular and cellular biology | | | 2001 | 653 | 0 |
|
| Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells | Molecular pharmacology | | | 2001 | 569 | 0 |
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| The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase | Molecular and cellular endocrinology | | | 2001 | 685 | 0 |
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| Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells. Mechanisms for its atheroprotective effects | The Journal of biological chemistry | | | 2000 | 645 | 0 |
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| Posttranslational regulation of proteins by fusions to steroid-binding domains | Methods in Enzymology, vol. 327 : Applications of chimeric genes and hybrid proteins, part B. Cell biology and physiology | | | 2000 | 570 | 0 |
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| The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest | FEBS letters | | | 2000 | 734 | 0 |
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| Ligand-independent activation of steroid receptors: new roles for old players | Trends in endocrinology and metabolism | | | 1999 | 672 | 0 |
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| Alpha-complemented beta-galactosidase. An in vivo model substrate for the molecular chaperone heat-shock protein 90 in yeast | European journal of biochemistry | | | 1999 | 883 | 3 |
|
| A yeast-based bioassay for the determination of functional and non-functional estrogen receptors | Nucleic acids research | | | 1999 | 568 | 276 |
|
| A non-radioactive method for inexpensive quantitative RT-PCR | Biological chemistry | | | 1999 | 670 | 0 |
|
| Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected] | Molecular and cellular biology | | | 1999 | 519 | 0 |
|
| Regulation of heterologous proteins by fusion to a hormone binding domain | Nuclear receptors : a practical approach | | | 1999 | 682 | 0 |
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| The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system | Biological chemistry | | | 1999 | 612 | 0 |
|
| Two compounds commonly used for phospholipase C inhibition activate the nuclear estrogen receptors | Biochemical and biophysical research communications | | | 1999 | 586 | 1 |
|
| Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha | Cancer research | | | 1999 | 542 | 1 |
|
| Bioactive steroids as contaminants of the common carbon source galactose | FEMS microbiology letters | | | 1998 | 595 | 0 |
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| Steroid-binding domains for regulating the functions of heterologous proteins in cis | Trends in cell biology | | | 1993 | 570 | 0 |
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