DP
Picard, Didier
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Phosphorylation of the Hsp90 Co-Chaperone Hop Changes its Conformational Dynamics and Biological Function | Journal of Molecular Biology | 2023 | 146 | 1 | |||
| Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer | Cellular and molecular life sciences | 2023 | 122 | 251 | |||
| CRISPR-Cas9 screen reveals a role of purine synthesis for estrogen receptor α activity and tamoxifen resistance of breast cancer cells | Science advances | 2023 | 89 | 311 | |||
| Hsf1 and the molecular chaperone Hsp90 support a ‘rewiring stress response’ leading to an adaptive cell size increase in chronic stress | eLife | 2023 | 98 | 195 | |||
| Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance | Biomolecules | 2022 | 166 | 587 | |||
| The Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and Inhibitors | Biomolecules | 2022 | 106 | 233 | |||
| Hyperactivation of MAPK Induces Tamoxifen Resistance in SPRED2-Deficient ERα-Positive Breast Cancer | Cancers | 2022 | 213 | 290 | |||
| Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis | Nature communications | 2022 | 186 | 102 | |||
| Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life | Nature communications | 2022 | 319 | 360 | |||
| H90-10 single-chain antibody recognizes Hsp90beta by immunoprecipitation and Western blotting | Antibody reports | 2021 | 188 | 113 | |||
| The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation | Nature Communications | 2020 | 307 | 248 | |||
| The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis | BMC Biology | 2020 | 352 | 163 | |||
| Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial | Analytica Chimica Acta | 2020 | 423 | 1 | |||
| Genetic ablation of MiR-22 fosters diet-induced obesity and NAFLD development | Journal of Personalized Medicine | 2020 | 353 | 208 | |||
| Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling | Nature Communications | 2019 | 529 | 273 | |||
| AI179 single-chain antibody recognizes the Myc tag by Western blotting | Antibody Reports | 2019 | 329 | 260 | |||
| The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity | PloS one | 2019 | 503 | 282 | |||
| A scoring approach for multi-platform acquisition in metabolomics | Journal of Chromatography. A | 2019 | 479 | 1 | |||
| AF291 and AE391 single-chain antibodies recognize the HA tag by Western blotting | Antibody Reports | 2019 | 533 | 204 | |||
| ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1 | Life Science Alliance | 2018 | 445 | 186 | |||
| Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development | Cell Stress and Chaperones | 2018 | 504 | 407 | |||
| Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes | Scientific Reports | 2018 | 434 | 222 | |||
| A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells | Oncotarget | 2017 | 535 | 220 | |||
| Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease | Brain | 2017 | 505 | 0 | |||
| Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol | ACS Medicinal Chemistry Letters | 2017 | 507 | 0 | |||
| H2B monoubiquitination: t'ub or not t'ub for inducible enhancers | Transcription | 2017 | 518 | 261 | |||
| Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model | Oncotarget | 2017 | 520 | 248 | |||
| Dendrogenin A drives LXR to trigger lethal autophagy in cancers | Nature Communications | 2017 | 582 | 400 | |||
| Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry | PLOS ONE | 2017 | 549 | 365 | |||
| Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23 | PloS one | 2017 | 454 | 212 | |||
| A remodeled Hsp90 molecular chaperone ensemble with the novel co-chaperone Aarsd1 is required for muscle differentiation | Molecular and cellular biology | 2016 | 513 | 287 | |||
| Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers | Molecular cell | 2016 | 594 | 418 | |||
| GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response | Scientific reports | 2016 | 595 | 363 | |||
| LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP | Nucleic acids research | 2016 | 573 | 404 | |||
| Unusual Suspects in the Twilight Zone Between the Hsp90 Interactome and Carcinogenesis | Hsp90 in Cancer: Beyond the Usual Suspects | 2016 | 608 | 1 | |||
| Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles | Journal of medicinal chemistry | 2016 | 499 | 0 | |||
| Minireview: Tipping the balance: ligand-independent activation of steroid receptors | Molecular endocrinology | 2015 | 868 | 1 | |||
| Overview of molecular chaperones in health and disease | Inhibitors of Molecular Chaperones as Therapeutic Agents | 2014 | 572 | 1 | |||
| Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors | Journal of medicinal chemistry | 2014 | 718 | 722 | |||
| A global view of the proteome perturbations by Hsp90 inhibitors | The Molecular Chaperones Interaction Networks in Protein Folding and Degradation | 2014 | 713 | 0 | |||
| Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells | Trends in cell biology | 2014 | 694 | 45 | |||
| Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 1,005 | 632 | |||
| Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on the T-Cell Proteome Have Implications for Anti-Cancer Therapy | PloS one | 2013 | 704 | 332 | |||
| The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter | The Journal of experimental medicine | 2013 | 800 | 661 | |||
| Preface to Hsp90 | Biochimica et biophysica acta. Molecular cell research | 2012 | 608 | 355 | |||
| An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine | PloS one | 2011 | 611 | 401 | |||
| Influenza Virus Infection Induces the Nuclear Relocalization of the Hsp90 Co-Chaperone p23 and Inhibits the Glucocorticoid Receptor Response | PloS one | 2011 | 782 | 350 | |||
| The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes | PloS one | 2011 | 564 | 582 | |||
| Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation | BioData mining | 2011 | 686 | 1,159 | |||
| CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP | Genes & development | 2010 | 624 | 0 | |||
| Multidirectional interplay between nuclear receptors and microRNAs | Current opinion in pharmacology | 2010 | 593 | 0 | |||
| Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility | Biochimica et biophysica acta | 2010 | 538 | 0 | |||
| The unfolding stories of GPR30, a new membrane-bound estrogen receptor | Journal of Endocrinology | 2010 | 1,018 | 0 | |||
| The molecular chaperone Hsp90alpha is required for meiotic progression of spermatocytes beyond pachytene in the mouse | PloS one | 2010 | 767 | 431 | |||
| miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA | Molecular and cellular biology | 2009 | 656 | 0 | |||
| The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities | Molecular and biochemical parasitology | 2009 | 799 | 0 | |||
| Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF | EMBO journal | 2009 | 1,383 | 1,011 | |||
| Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells | Endocrinology | 2008 | 1,111 | 0 | |||
| Genomics of signaling crosstalk of estrogen receptor alpha in breast cancer cells | PloS one | 2008 | 569 | 299 | |||
| A stress protein interface of innate immunity | EMBO reports | 2008 | 622 | 243 | |||
| The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation | Immunity | 2008 | 575 | 0 | |||
| p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity | Molecular and cellular biology | 2008 | 734 | 0 | |||
| The glucocorticoid responses are shaped by molecular chaperones | Molecular and cellular endocrinology | 2007 | 563 | 0 | |||
| Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome | Digestive diseases and sciences | 2007 | 624 | 522 | |||
| Chaperoning steroid hormone action | Trends in endocrinology and metabolism | 2006 | 651 | 0 | |||
| Fungi and animals may share a common ancestor to nuclear receptors | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 564 | 0 | |||
| Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90 | Experimental cell research | 2006 | 560 | 1 | |||
| The cell-specific activity of the estrogen receptor alpha may be fine-tuned by phosphorylation-induced structural gymnastics | Nuclear receptor signaling | 2006 | 611 | 252 | |||
| The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells | Molecular endocrinology | 2006 | 895 | 0 | |||
| 2-color photobleaching experiments reveal distinct intracellular dynamics of two components of the Hsp90 complex | Experimental cell research | 2006 | 620 | 2 | |||
| The Hsp90 cochaperone p23 is essential for perinatal survival | Molecular and cellular biology | 2006 | 654 | 1 | |||
| [Retracted] 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30 | Molecular pharmacology | 2006 | 1,109 | 0 | |||
| Bioluminescent yeast assays for detecting estrogenic and androgenic activity in different matrices | Chemosphere | 2005 | 616 | 1 | |||
| LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes | Human molecular genetics | 2005 | 658 | 0 | |||
| siRNA production by in vitro transcription | Gene silencing by RNA interference : technology and application | 2005 | 626 | 1 | |||
| A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90alpha | Biochemical and biophysical research communications | 2005 | 572 | 2 | |||
| SPBP is a phosphoserine-specific repressor of estrogen receptor alpha | Molecular and cellular biology | 2005 | 571 | 0 | |||
| The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells | The Journal of biological chemistry | 2004 | 825 | 0 | |||
| A web application to manage a database for liquid nitrogen tanks | Immunology and cell biology | 2004 | 594 | 1 | |||
| A recombinant yeast strain as a short term bioassay to assess estrogen-like activity of xenobiotics | Annali di igiene medicina preventiva e di comunità | 2004 | 461 | 0 | |||
| The protein kinase PKR: a molecular clock that sequentially activates survival and death programs | EMBO journal | 2004 | 600 | 0 | |||
| TROD: T7 RNAi oligo designer | Nucleic acids research | 2004 | 683 | 394 | |||
| Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells | Journal of molecular endocrinology | 2004 | 623 | 0 | |||
| Hsp90 invades the outside | Nature cell biology | 2004 | 525 | 0 | |||
| The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo | EMBO journal | 2003 | 616 | 0 | |||
| Molecular mechanisms of cross-talk between growth factors and nuclear receptor signaling | Pure and applied chemistry | 2003 | 603 | 574 | |||
| Cdc37 goes beyond Hsp90 and kinases | Cell stress & chaperones | 2003 | 624 | 3 | |||
| Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation | Molecular and cellular biology | 2002 | 548 | 0 | |||
| Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells | Molecular and cellular endocrinology | 2002 | 648 | 0 | |||
| Heat-shock protein 90, a chaperone for folding and regulation | Cellular and molecular life sciences | 2002 | 669 | 2 | |||
| The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically | Biological chemistry | 2002 | 654 | 0 | |||
| RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase | Nucleic acids research | 2002 | 599 | 325 | |||
| The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR | EMBO journal | 2001 | 643 | 0 | |||
| Hsp104 interacts with Hsp90 cochaperones in respiring yeast | Molecular and cellular biology | 2001 | 641 | 0 | |||
| Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells | Molecular pharmacology | 2001 | 551 | 0 | |||
| The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase | Molecular and cellular endocrinology | 2001 | 672 | 0 | |||
| Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells. Mechanisms for its atheroprotective effects | The Journal of biological chemistry | 2000 | 630 | 0 | |||
| Posttranslational regulation of proteins by fusions to steroid-binding domains | Methods in Enzymology, vol. 327 : Applications of chimeric genes and hybrid proteins, part B. Cell biology and physiology | 2000 | 556 | 0 | |||
| The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest | FEBS letters | 2000 | 719 | 0 | |||
| Ligand-independent activation of steroid receptors: new roles for old players | Trends in endocrinology and metabolism | 1999 | 659 | 0 | |||
| Alpha-complemented beta-galactosidase. An in vivo model substrate for the molecular chaperone heat-shock protein 90 in yeast | European journal of biochemistry | 1999 | 867 | 3 | |||
| A yeast-based bioassay for the determination of functional and non-functional estrogen receptors | Nucleic acids research | 1999 | 552 | 232 | |||
| A non-radioactive method for inexpensive quantitative RT-PCR | Biological chemistry | 1999 | 652 | 0 | |||
| Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected] | Molecular and cellular biology | 1999 | 507 | 0 | |||
| Regulation of heterologous proteins by fusion to a hormone binding domain | Nuclear receptors : a practical approach | 1999 | 669 | 0 | |||
| The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system | Biological chemistry | 1999 | 592 | 0 | |||
| Two compounds commonly used for phospholipase C inhibition activate the nuclear estrogen receptors | Biochemical and biophysical research communications | 1999 | 571 | 1 | |||
| Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha | Cancer research | 1999 | 529 | 1 | |||
| Bioactive steroids as contaminants of the common carbon source galactose | FEMS microbiology letters | 1998 | 581 | 0 | |||
| Steroid-binding domains for regulating the functions of heterologous proteins in cis | Trends in cell biology | 1993 | 554 | 0 |
