DP
Picard, Didier
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Phosphorylation of the Hsp90 Co-Chaperone Hop Changes its Conformational Dynamics and Biological Function | Journal of Molecular Biology | 2023 | 149 | 1 | |||
| Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer | Cellular and molecular life sciences | 2023 | 123 | 287 | |||
| CRISPR-Cas9 screen reveals a role of purine synthesis for estrogen receptor α activity and tamoxifen resistance of breast cancer cells | Science advances | 2023 | 91 | 364 | |||
| Hsf1 and the molecular chaperone Hsp90 support a ‘rewiring stress response’ leading to an adaptive cell size increase in chronic stress | eLife | 2023 | 100 | 205 | |||
| Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance | Biomolecules | 2022 | 167 | 723 | |||
| The Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and Inhibitors | Biomolecules | 2022 | 110 | 302 | |||
| Hyperactivation of MAPK Induces Tamoxifen Resistance in SPRED2-Deficient ERα-Positive Breast Cancer | Cancers | 2022 | 214 | 313 | |||
| Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis | Nature communications | 2022 | 188 | 104 | |||
| Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life | Nature communications | 2022 | 322 | 426 | |||
| The Hsp70–Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration | Cellular and molecular life sciences | 2021 | 1 | 0 | |||
| H90-10 single-chain antibody recognizes Hsp90beta by immunoprecipitation and Western blotting | Antibody reports | 2021 | 189 | 122 | |||
| The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation | Nature Communications | 2020 | 307 | 249 | |||
| The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis | BMC Biology | 2020 | 354 | 168 | |||
| Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial | Analytica Chimica Acta | 2020 | 425 | 1 | |||
| Genetic ablation of MiR-22 fosters diet-induced obesity and NAFLD development | Journal of Personalized Medicine | 2020 | 357 | 213 | |||
| Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling | Nature Communications | 2019 | 529 | 277 | |||
| AI179 single-chain antibody recognizes the Myc tag by Western blotting | Antibody Reports | 2019 | 332 | 290 | |||
| The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity | PloS one | 2019 | 507 | 305 | |||
| A scoring approach for multi-platform acquisition in metabolomics | Journal of Chromatography. A | 2019 | 485 | 1 | |||
| AF291 and AE391 single-chain antibodies recognize the HA tag by Western blotting | Antibody Reports | 2019 | 535 | 228 | |||
| ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1 | Life Science Alliance | 2018 | 448 | 192 | |||
| Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development | Cell Stress and Chaperones | 2018 | 506 | 499 | |||
| Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes | Scientific Reports | 2018 | 434 | 223 | |||
| A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells | Oncotarget | 2017 | 536 | 241 | |||
| Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease | Brain | 2017 | 509 | 0 | |||
| Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol | ACS Medicinal Chemistry Letters | 2017 | 509 | 0 | |||
| H2B monoubiquitination: t'ub or not t'ub for inducible enhancers | Transcription | 2017 | 520 | 296 | |||
| Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model | Oncotarget | 2017 | 522 | 255 | |||
| Dendrogenin A drives LXR to trigger lethal autophagy in cancers | Nature Communications | 2017 | 582 | 434 | |||
| Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry | PLOS ONE | 2017 | 552 | 407 | |||
| Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23 | PloS one | 2017 | 457 | 238 | |||
| A remodeled Hsp90 molecular chaperone ensemble with the novel co-chaperone Aarsd1 is required for muscle differentiation | Molecular and cellular biology | 2016 | 516 | 298 | |||
| Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers | Molecular cell | 2016 | 597 | 462 | |||
| GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response | Scientific reports | 2016 | 598 | 369 | |||
| LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP | Nucleic acids research | 2016 | 584 | 428 | |||
| Unusual Suspects in the Twilight Zone Between the Hsp90 Interactome and Carcinogenesis | Hsp90 in Cancer: Beyond the Usual Suspects | 2016 | 614 | 1 | |||
| Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles | Journal of medicinal chemistry | 2016 | 502 | 0 | |||
| Minireview: Tipping the balance: ligand-independent activation of steroid receptors | Molecular endocrinology | 2015 | 869 | 1 | |||
| Overview of molecular chaperones in health and disease | Inhibitors of Molecular Chaperones as Therapeutic Agents | 2014 | 576 | 1 | |||
| Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors | Journal of medicinal chemistry | 2014 | 719 | 745 | |||
| A global view of the proteome perturbations by Hsp90 inhibitors | The Molecular Chaperones Interaction Networks in Protein Folding and Degradation | 2014 | 714 | 0 | |||
| Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells | Trends in cell biology | 2014 | 695 | 45 | |||
| Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 1,006 | 655 | |||
| Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on the T-Cell Proteome Have Implications for Anti-Cancer Therapy | PloS one | 2013 | 705 | 345 | |||
| The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter | The Journal of experimental medicine | 2013 | 802 | 671 | |||
| Preface to Hsp90 | Biochimica et biophysica acta. Molecular cell research | 2012 | 611 | 374 | |||
| An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine | PloS one | 2011 | 613 | 405 | |||
| Influenza Virus Infection Induces the Nuclear Relocalization of the Hsp90 Co-Chaperone p23 and Inhibits the Glucocorticoid Receptor Response | PloS one | 2011 | 785 | 374 | |||
| The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes | PloS one | 2011 | 566 | 611 | |||
| Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation | BioData mining | 2011 | 694 | 1,171 | |||
| CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP | Genes & development | 2010 | 625 | 0 | |||
| Multidirectional interplay between nuclear receptors and microRNAs | Current opinion in pharmacology | 2010 | 596 | 0 | |||
| Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility | Biochimica et biophysica acta | 2010 | 540 | 0 | |||
| The unfolding stories of GPR30, a new membrane-bound estrogen receptor | Journal of Endocrinology | 2010 | 1,021 | 0 | |||
| The molecular chaperone Hsp90alpha is required for meiotic progression of spermatocytes beyond pachytene in the mouse | PloS one | 2010 | 768 | 457 | |||
| miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA | Molecular and cellular biology | 2009 | 659 | 0 | |||
| The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities | Molecular and biochemical parasitology | 2009 | 805 | 0 | |||
| Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF | EMBO journal | 2009 | 1,383 | 1,027 | |||
| Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells | Endocrinology | 2008 | 1,116 | 0 | |||
| Genomics of signaling crosstalk of estrogen receptor alpha in breast cancer cells | PloS one | 2008 | 575 | 311 | |||
| A stress protein interface of innate immunity | EMBO reports | 2008 | 627 | 245 | |||
| The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation | Immunity | 2008 | 577 | 0 | |||
| p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity | Molecular and cellular biology | 2008 | 737 | 0 | |||
| The glucocorticoid responses are shaped by molecular chaperones | Molecular and cellular endocrinology | 2007 | 567 | 0 | |||
| Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome | Digestive diseases and sciences | 2007 | 627 | 541 | |||
| Chaperoning steroid hormone action | Trends in endocrinology and metabolism | 2006 | 653 | 0 | |||
| Fungi and animals may share a common ancestor to nuclear receptors | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 567 | 0 | |||
| Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90 | Experimental cell research | 2006 | 561 | 1 | |||
| The cell-specific activity of the estrogen receptor alpha may be fine-tuned by phosphorylation-induced structural gymnastics | Nuclear receptor signaling | 2006 | 620 | 258 | |||
| The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells | Molecular endocrinology | 2006 | 898 | 0 | |||
| 2-color photobleaching experiments reveal distinct intracellular dynamics of two components of the Hsp90 complex | Experimental cell research | 2006 | 626 | 2 | |||
| The Hsp90 cochaperone p23 is essential for perinatal survival | Molecular and cellular biology | 2006 | 655 | 1 | |||
| [Retracted] 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30 | Molecular pharmacology | 2006 | 1,111 | 0 | |||
| Bioluminescent yeast assays for detecting estrogenic and androgenic activity in different matrices | Chemosphere | 2005 | 619 | 1 | |||
| LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes | Human molecular genetics | 2005 | 661 | 0 | |||
| siRNA production by in vitro transcription | Gene silencing by RNA interference : technology and application | 2005 | 629 | 1 | |||
| A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90alpha | Biochemical and biophysical research communications | 2005 | 576 | 2 | |||
| SPBP is a phosphoserine-specific repressor of estrogen receptor alpha | Molecular and cellular biology | 2005 | 575 | 0 | |||
| The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells | The Journal of biological chemistry | 2004 | 828 | 0 | |||
| A web application to manage a database for liquid nitrogen tanks | Immunology and cell biology | 2004 | 597 | 1 | |||
| A recombinant yeast strain as a short term bioassay to assess estrogen-like activity of xenobiotics | Annali di igiene medicina preventiva e di comunità | 2004 | 465 | 0 | |||
| The protein kinase PKR: a molecular clock that sequentially activates survival and death programs | EMBO journal | 2004 | 605 | 0 | |||
| TROD: T7 RNAi oligo designer | Nucleic acids research | 2004 | 684 | 405 | |||
| Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells | Journal of molecular endocrinology | 2004 | 626 | 0 | |||
| Hsp90 invades the outside | Nature cell biology | 2004 | 528 | 0 | |||
| The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo | EMBO journal | 2003 | 617 | 0 | |||
| Molecular mechanisms of cross-talk between growth factors and nuclear receptor signaling | Pure and applied chemistry | 2003 | 608 | 609 | |||
| Cdc37 goes beyond Hsp90 and kinases | Cell stress & chaperones | 2003 | 626 | 3 | |||
| Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation | Molecular and cellular biology | 2002 | 550 | 0 | |||
| Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells | Molecular and cellular endocrinology | 2002 | 650 | 0 | |||
| Heat-shock protein 90, a chaperone for folding and regulation | Cellular and molecular life sciences | 2002 | 671 | 2 | |||
| The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically | Biological chemistry | 2002 | 656 | 0 | |||
| RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase | Nucleic acids research | 2002 | 600 | 332 | |||
| The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR | EMBO journal | 2001 | 645 | 0 | |||
| Hsp104 interacts with Hsp90 cochaperones in respiring yeast | Molecular and cellular biology | 2001 | 643 | 0 | |||
| Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells | Molecular pharmacology | 2001 | 556 | 0 | |||
| The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase | Molecular and cellular endocrinology | 2001 | 674 | 0 | |||
| Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells. Mechanisms for its atheroprotective effects | The Journal of biological chemistry | 2000 | 634 | 0 | |||
| Posttranslational regulation of proteins by fusions to steroid-binding domains | Methods in Enzymology, vol. 327 : Applications of chimeric genes and hybrid proteins, part B. Cell biology and physiology | 2000 | 558 | 0 | |||
| The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest | FEBS letters | 2000 | 723 | 0 | |||
| Ligand-independent activation of steroid receptors: new roles for old players | Trends in endocrinology and metabolism | 1999 | 661 | 0 | |||
| Alpha-complemented beta-galactosidase. An in vivo model substrate for the molecular chaperone heat-shock protein 90 in yeast | European journal of biochemistry | 1999 | 873 | 3 | |||
| A yeast-based bioassay for the determination of functional and non-functional estrogen receptors | Nucleic acids research | 1999 | 557 | 245 | |||
| A non-radioactive method for inexpensive quantitative RT-PCR | Biological chemistry | 1999 | 659 | 0 | |||
| Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected] | Molecular and cellular biology | 1999 | 508 | 0 | |||
| Regulation of heterologous proteins by fusion to a hormone binding domain | Nuclear receptors : a practical approach | 1999 | 672 | 0 | |||
| The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system | Biological chemistry | 1999 | 597 | 0 | |||
| Two compounds commonly used for phospholipase C inhibition activate the nuclear estrogen receptors | Biochemical and biophysical research communications | 1999 | 576 | 1 | |||
| Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha | Cancer research | 1999 | 532 | 1 | |||
| Bioactive steroids as contaminants of the common carbon source galactose | FEMS microbiology letters | 1998 | 585 | 0 | |||
| Steroid-binding domains for regulating the functions of heterologous proteins in cis | Trends in cell biology | 1993 | 558 | 0 |
