The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells
Contributeurs/tricesVivacqua, Adele; Bonofiglio, Daniela; Recchia, Anna Grazia; Musti, Anna Maria; Picard, Didier![orcid](assets/images/orcid.png)
; Andò, Sebastiano; Maggiolini, Marcello
![orcid](assets/images/orcid.png)
Publié dansMolecular endocrinology, vol. 20, no. 3, p. 631-646
Date de publication2006
Résumé
Mots-clés
- 1-Phosphatidylinositol 3-Kinase/antagonists & inhibitors/metabolism
- Androstadienes/pharmacology
- Cell Proliferation/drug effects
- Endometrial Neoplasms/drug therapy/metabolism/pathology
- Enzyme Activation/drug effects
- Enzyme Inhibitors/pharmacology
- Estradiol/pharmacology
- Estrogen Receptor alpha/drug effects/metabolism
- Female
- Flavonoids/pharmacology
- Gene Expression Regulation, Neoplastic/drug effects
- Humans
- MAP Kinase Signaling System/drug effects
- Promoter Regions, Genetic
- Protein Splicing
- Proto-Oncogene Proteins c-fos/drug effects/genetics/metabolism
- Receptors, G-Protein-Coupled/drug effects/metabolism
- Selective Estrogen Receptor Modulators/pharmacology
- Tamoxifen/analogs & derivatives/pharmacology
- Transcriptional Activation
- Tumor Cells, Cultured
- Up-Regulation
Structure d'affiliation
Citation (format ISO)
VIVACQUA, Adele et al. The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells. In: Molecular endocrinology, 2006, vol. 20, n° 3, p. 631–646. doi: 10.1210/me.2005-0280
Fichiers principaux (1)
Article (Published version)
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Identifiants
- PID : unige:4590
- DOI : 10.1210/me.2005-0280
- PMID : 16239258
ISSN du journal0888-8809