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Scientific Article
unige:4617 
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Hsp90 invades the outside |
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| Author | ||
| Published in | Nature Cell Biology. 2004, vol. 6, no. 6, p. 479-80 | |
| Abstract | Metalloproteases are required for the invasive nature of cancer cells. Surprisingly, the cytosolic molecular chaperone Hsp90 is now shown to promote maturation of the extracellular metalloprotease MMP2. This finding extends the multiplicity of roles assigned to the Hsp90 family to a new function outside the cell. | |
| Keywords | Antigens, Neoplasm/metabolism — Basement Membrane/metabolism — Cell Movement/physiology — Extracellular Matrix/metabolism — HSP90 Heat-Shock Proteins/metabolism — Matrix Metalloproteinase 2/metabolism — Neoplasm Invasiveness/genetics | |
| Identifiers | DOI: 10.1038/ncb0604-479 PMID: 15170457 | |
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| Citation (ISO format) | PICARD, Didier. Hsp90 invades the outside. In: Nature Cell Biology, 2004, vol. 6, n° 6, p. 479-80. https://archive-ouverte.unige.ch/unige:4617 |
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